General State Research Articles

ВЗАИМОСВЯЗЬ СОСТОЯНИЯ ЗДОРОВЬЯ НАСЕЛЕНИЯ И ПРИБЫЛЬНОСТИ В ПРОДОВОЛЬСТВЕННОЙ СФЕРЕ

The aim of the study is to develop theoretical provisions of the dependence of the general integrated state of health of the population on the total aggregate profit indi-cator of the food business. The subject of the study is the mechanism of the relation-ship between the state of health and profitability of the food business. A number of literary sources devoted to the gen-eralization of the state of health and economic development of the country are considered. The theoretical dependence of the integral indicator of health status on the total cumulative rate of total profit of the agro-industrial complex, the food industry and food retail is proved. The variants of changing the state of health with different parameters of its parabolic dependence on the total profitability of the food business are considered. A conditional numerical example of the dependence of the state of health in the form of a cubic parabola on the change in the total cumulative rate of profit of the food business is presented and analyzed. It is concluded that the main task of establishing and achieving health indicators (the general goal) is not only market, but also state provision with appropriate parameters of the overall total profitability of the food food business. It is proved that the growth of profitability (profitability) of food sales affects the change in the health status of the population in terms of eating disorders and metabolic disorders.

Physics-Informed Graphical Learning and Bayesian Averaging for Robust Distribution State Estimation

This paper proposes a robust topology change-aware distribution system state estimation (DSSE) method based on a physics-informed graph neural network and Bayesian Probability Weighted Averaging (BPWA). A general state estimator is first built utilizing a graph attention network to learn the nonlinear mapping functions under different distribution network topologies. During this stage, the topology information is embedded in the neural network and the attention mechanism is employed to capture collaborative signals and discriminate the importance of neighboring buses. Then, the BPWA method allows assigning proper weights for the state estimation results under different topologies, which finally yields a single consensus solution via the sparse training samples under the new topology. The physics-informed mechanism enables the proposed method to embed the topology knowledge in the neural network while fully exploiting the value of historical data. Robustness to anomalous measurements is achieved through the embedding of physics knowledge. The application of the BPWA method further allows the proposed method to achieve faster adaptation to topology change and quantification of the estimation uncertainties by measurement errors. MATLAB and Python are used to carry out the comparative tests to evaluate the performance of the proposed method.

Tripartite prehabilitation of patients with acute myeloid leukaemia and high-risk myelodysplastic syndromes during intensive chemotherapy before allogeneic haematopoietic stem cell transplantation (COHABILIT): protocol for an innovating prospective multicentre study

ObjectivesAcute myeloid leukaemia (AML) and high-risk myelodysplastic syndromes (MDS) are often treated with intensive chemotherapy followed by allogeneic haematopoietic stem cell transplantation (allo-HSCT). The pretransplant treatment results in a general...

Assessment of The Reliability of The Portuguese Republic Financial Report (2010 To 2019)

Objective: Accountability and transparency are essential values within the New Public Governance, in which reporting emerges as an instrument of accountability from public managers to stakeholders. In this context, the research aims to study the reliability of the Financial Reporting of the Portuguese State from 2010 to 2019. Method: The investigation method was the case study. It was analysed the limitations disclosed in the Opinions of the General State Account, issued by the Court of Auditors, (TdC), from 2010 to 2019. Data have been classified to carry out the descriptive analysis, allowing the interpretation of the information. Results: It can be concluded that the reliability of the Portuguese State's financial reporting is conditioned, namely by limitations of the scope and by the existence of material errors. Also, the lack of consolidated financial information and an accounting system that allows the integrated recording of State operations, as provided for in the legislation, affects the transparency and reliability of the General State Account. These constraints also limit the issuing of an opinion by the Court of Auditors under the International Standards on Auditing. Originality/Relevance: There is no known research on the reliability of the financial reporting of the Portuguese State, which is essential for the desired transparency. Theoretical/methodological contributions: The study contributes to the knowledge of the public sector transparency, meeting the stakeholders’ requirements for good governance practices and accountability.

Holographic tensor networks with bulk gauge symmetries

Tensor networks are useful toy models for understanding the structure of entanglement in holographic states and reconstruction of bulk operators within the entanglement wedge. They are, however, constrained to only prepare so-called “fixed-area states” with flat entanglement spectra, limiting their utility in understanding general features of holographic entanglement. Here, we overcome this limitation by constructing a variant of random tensor networks that enjoys bulk gauge symmetries. Our model includes a gauge theory on a general graph, whose gauge-invariant states are fed into a random tensor network. We show that the model satisfies the quantum-corrected Ryu-Takayanagi formula with a nontrivial area operator living in the center of a gauge-invariant algebra. We also demonstrate nontrivial, n-dependent contributions to the Rényi entropy and Rényi mutual information from this area operator, a feature shared by general holographic states.

Ретроспективний аналіз каріозного ураження твердих тканин зубів у дітей з радіаційно забруднених унаслідок аварії на Чорнобильській АЕС територій України

The relevance of the study is due to the presence of significant carious lesions of the hard tissues of the teeth in children from radiation-contaminated territories as a result of the accident at the Chornobyl nuclear power plant (ChNPP). Purpose - to conduct a retrospective analysis of the intensity of dental caries in children of Ukraine, residents of radiation-contaminated territories, taking into account the general state of health at different times after the accident at the ChNPP (1993-1996, 2001-2003, 2016-2018) as a basis for the further development of a complex of therapeutic and preventive measures for this pathology. Materials and methods. The object of the study: 1852 children aged 7-15 - residents of territories contaminated with radionuclides. Assessment of caries intensity of permanent teeth in accordance with WHO recommendations (2013) included determination of caries prevalence and index assessment of caries intensity of permanent teeth (PT): «decayed, missing, filled permanent teeth» (DMFT) and «decayed, missing, filled permanent teeth surfaces» (DMFS). Statistical processing of data was carried out using methods of variational statistics (statistical package «IBM SPSS Statistics 20.0.0»). Results. In 1993-1996 irradiated children from the III zone had a very high intensity of dental caries (DMFT - 7.25±0.77, DMFS - 10.92±1.77), twice as high compared to residents of the IV zone. In children from III and IV zones in 2001-2003 the intensity of dental caries was higher in the presence of somatic pathology. In 2016-2018 compared to the period 2001-2003 there was a significant (p<0.05) decrease in both indices of carious lesions, probably due to a decrease in the degree of exposure of children to radionuclides. Conclusions. During the period 1993-1996 the highest rates of dental caries intensity were determined in 15-year-old children from zone III compared to residents of zone IV. The intensity of dental caries during the periods of 2001-2003 and 2016-2018 decreased, although it remained at a high level, which requires the further development of a complex of treatment and prevention measures for this pathology. The research was carried out in accordance with the principles of the Declaration of Helsinki. The research protocol was approved by the Local Ethics Committee of the institution mentioned in the work. Informed consent of the children's parents was obtained for the research. The authors declare no conflict of interests.

Investigating entangled photons to quantify quantum correlations in dual optomechanical cavities.

Quantum correlations that go beyond quantum entanglement have a significant role in the fields of quantum information processing and quantum computation. In essence, when we describe a quantum system using pure states, quantum entanglement and quantum correlation are essentially indistinguishable. However, this equivalence breaks down when dealing with general mixed states. To contribute to understanding this distinction, we have considered a straightforward model for both generating and measuring these quantum correlations. We focus on two macroscopic mechanical resonators situated in separate Fabry–Perot cavities and coupled through the photon hopping process. Our model allows us to conduct a comprehensive examination and quantification of quantum correlations that extend beyond entanglement between these mechanical modes. Our approach begins with the determination of the global covariance matrix, serving as the foundation for calculating two key metrics: the Entropy of Formation and the Gaussian quantum Discord. These metrics enable us to quantify the extent of quantum entanglement and quantum correlations, respectively. Our analysis, based on these quantifiers, reveals that quantum discord serves as a more appropriate metric for characterizing the quantum correlations between the mechanical modes in an optomechanical quantum system, especially in the presence of robust photon hopping.

Non-geometric BPS branes on T-folds

We give a detailed (microscopic) description of the geometric and non-geometric fundamental branes and their bound states in Type II superstring compactifications preserving N\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$ \\mathcal{N} $$\\end{document} = 6 supersymmetry. We consider general boundary states that couple to the twisted sector and compute the relevant annulus amplitudes. We check consistency of the construction by relating the ‘transverse’ channel, corresponding to closed-string ‘tree-level’ exchange, with the ‘direct’ open-string loop channel. Focussing on the Type IIA frame, we show that D0-D4 have the expected tension for a geometric brane, while the non-geometric D2-D6 boundary states have a tension equal to 1/K\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$ 1/\\sqrt{K} $$\\end{document} the one of a geometric brane for the ZK orbifold. This is consistent with Fricke T-duality of the N\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$ \\mathcal{N} $$\\end{document} = 6 model.

Prescriptive method for fiber polarization compensation in two bases.

Single-mode optical fibers exhibit a small but non-negligible birefringence that induces random polarization rotations during light propagation. In classical interferometry these rotations give rise to polarization-induced fading of the interferometric visibility, and in fiber-based polarimetric sensors as well as quantum optics experiments, they scramble the information encoded in the polarization state. Correcting these undesired rotations is consequently an important part of many experiments and applications employing optical fibers. In this Lab Note we review an efficient method for fully compensating fiber polarization rotations for general input states. This method was not originally devised by us, but does, to the best of our knowledge, not appear in the literature, and our interactions with the community have indicated that it is not well known.

The use of soybeans in the structure of the ration of high-yielding cows

In the conditions of intensive milk production in order to ensure high productivity and at the same time preserve the general functional state of animal health it is impossible to do without the use of protein-rich grain components in the structure of compound feed. These include soybeans, which in the western region of Ukraine began to be widely used in the production of compound feed for cattle. The percentage of introduction of soybeans into the structure of compound feed is different and for high-yielding cows requires additional study, which explains the relevance of conducting research on its influence on milk productivity, quality indicators of milk against the background of assimilation of the main nutrients of feed. The study was conducted on four groups of Simmental cows, seven heads in each. The rations of experimental cows provided for three levels of provision of protein needs at the expense of soybeans and were balanced in terms of basic nutrients in compliance with the requirements of detailed requirements. The analysis of the feeding conditions of experimental cows showed that the use of heat-treated soybeans in the structure of the ration contributed to a significant increase in milk productivity, as well as quality indicators, the content of dry matter, fat, protein, calcium and phosphorus. A similar pattern was observed in terms of indicators of the intensity of metabolic processes of cicatricial digestion. Thus, a positive effect on the percentage of certain volatile fatty acids, in particular acetic as a precursor of milk fat was noted. An increase was noted in the digestibility indicators of the main nutrients (protein, fat, fiber digestibility coefficients). The positive effect of soybeans on the milk productivity of the experimental cows was also noted by the results of the balance experiment. The nitrogen balance was positive and its use for milk production in cows of the fourth group compared to the control group was 27.4 % higher. A similar trend was observed in the balance of calcium and phosphorus. So, the conducted studies on the study of the productive effect of different amounts of soybeans instead of cereal components in the structure of compound feed on milk productivity give reason to recommend that farms use prepared soybeans in the proportion of 10–15 % in compound feed for high-yielding cows.

The developmental role of tourism in rural areas

Rural areas in the Republic of Serbia occupy about 85% of the territory, where about 55% of the total population lives, while in the Republic of Srpska rural areas occupy about 95% of the territory and about 83% of its population lives in them. Rural tourism is a common name for various activities and forms of tourism that occur outside cities, ie urban areas and those areas where mass tourism has developed. It is conditioned by the tourist attractions that are located in these rural areas. The importance of rural tourism is reflected, above all, in the very important interaction of agricultural production, traditional agri-food products, presentation of traditions, traditional gastronomy and tourist services, and the use of already existing resources. Considering that the statistics of rural development capacity in Serbia and Republic of Srpska are based on estimates, it is assumed that a significant part of overnight stays, which are realized in spa and mountain areas, can also be treated as realized overnight stays in the field of rural tourist offer. Observing the general state of rural development in the Republic of Serbia and the Republic of Srpska, it can be noticed that there are a number of limiting factors that condition the unenviable position of the rural tourist product on the tourist market. Some of them are as follows: low level of achieved quality of services provided, insufficient knowledge of new approaches to rural economy development in both competitive domestic and foreign tourism markets, lack of adequate institutional framework to ensure the coordinating role of the state and greater involvement of local authorities. in integrated rural development, poorly developed infrastructure, inadequate diversification of activities, dominance of sectoral policies. Respecting the census of agriculture and the statistical definition of agricultural holdings, the importance of a rural tourist household, ie a household located in a rural area and engaged in tourism, or as a more appropriate name for a tourist family farm must be mentioned. In addition to tourism in rural tourist households, in rural areas we encounter many special forms of tourism. Tourism in rural areas equally includes the activities of tourists (multi-day visitors) and excursionists (one-day visitors). Rural tourist households are generally considered to be basic rural tourism. However, for the development of rural tourism, not only rural tourist households are sufficient, but also other facilities on the rural tourist household itself and in the rural area. Other catering infrastructure is also needed: rooms and canopies for serving food, rooms for wine tasting, brandy, fruit and vegetable products, arranged approaches to the rural tourist household and parking lot, arranged tourist attractions (real, tourist available), restaurants, defined wine and brandy roads, marked bicycle and hiking trails, pilgrimage routes, receptive tourist agencies, ie designed and organized rural tourist destinations are needed, with all possible feasible contents of the tourist rural product. The quality of the rural tourist offer is affirmed as an important factor only in the new age, after it has been in the background for a long time, ie in the shadow of quantitative values. For each destination or company, it is important to be competitive in order to successfully sell their products on the market, and enable loyal tourists. In order for the quality to achieve its true level of development, certain specific circumstances should be determined, and that, along with modern technological development, is a very intensified competitive competition, especially pronounced on the global market.

Unified catalytic entropy principles of general states

Unified catalytic entropy principles of general states

Primal-Dual Regression Approach for Markov Decision Processes with General State and Action Spaces

Primal-Dual Regression Approach for Markov Decision Processes with General State and Action Spaces

Gaussian boson sampling with click-counting detectors

Gaussian boson sampling constitutes a prime candidate for an experimental demonstration of quantum advantage within reach with current technological capabilities. The original proposal employs photon-number-resolving detectors, however, these are not widely available. Nevertheless, inexpensive threshold detectors can be combined into a single click-counting detector to achieve approximate photon-number resolution. We investigate the problem of sampling from a general multimode Gaussian state using click-counting detectors and show that the probability of obtaining a given outcome is related to a matrix function which is dubbed as the Kensingtonian. We show how the Kensingtonian relates to the Torontonian and the Hafnian, thus bridging the gap between known Gaussian boson sampling variants. We then prove that, under standard complexity-theoretical conjectures, the model cannot be simulated efficiently. Published by the American Physical Society 2024

Entanglement and entropy in multipartite systems: a useful approach

Quantum entanglement and quantum entropy are crucial concepts in the study of multipartite quantum systems. In this work, we show how the notion of concurrence vector, re-expressed in a particularly useful form, provides new insights and computational tools for the analysis of both. In particular, using this approach for a general multipartite pure state, one can easily prove known relations in an easy way and to build up new relations between the concurrences associated with the different bipartitions. The approach is also useful to derive sufficient conditions for genuine entanglement in generic multipartite systems that are computable in polynomial time. From an entropy-of-entanglement perspective, the approach is powerful to prove properties of the Tsallis-2 entropy, such as the subadditivity, and to derive new ones, e.g., a modified version of the strong subadditivity which is always fulfilled; thanks to the purification theorem these results hold for any multipartite state, whether pure or mixed.

Cognitive behavioural therapy without medication for schizophrenia.

Cognitive behavioural therapy (CBT) can be effective in people with schizophrenia when provided in combination with antipsychotic medication. It remains unclear whether CBT could be safely and effectively offered in the absence of concomitant antipsychotic therapy. To investigate the effects of CBT for schizophrenia when administered without concomitant pharmacological treatment with antipsychotics. We conducted a systematic search on 6 March 2022 in the Cochrane Schizophrenia Group's Study-Based Register of Trials, which is based on CENTRAL, MEDLINE, Embase, CINAHL, PsycINFO, PubMed, ClinicalTrials.gov, and WHO ICTRP. We included randomised controlled trials (RCTs) in people with schizophrenia comparing CBT without antipsychotics to standard care, standard care without antipsychotics, or the combination of CBT and antipsychotics. Two review authors independently screened references for inclusion, extracted data from eligible studies, and assessed risk of bias using Cochrane's RoB 2 tool. We contacted study authors for missing data and additional information. Our primary outcome was general mental state measured with a validated rating scale. Key secondary outcomes were specific symptoms of schizophrenia, relapse, service use, number of participants leaving the study early, functioning, quality of life, and number of participants actually receiving antipsychotics during the trial. We also assessed behaviour, adverse effects, and mortality. We included 4 studies providing data for 300 participants (average age 21.94 years). The mean sample size was 75 participants (range 61 to 90 participants). Study duration was between 26 and 39 weeks for the intervention period and 26 to 104 weeks for the follow-up period. Three studies employed a blind rater, while one study was triple-blind. All analyses included data from a maximum of three studies. The certainty of the evidence was low or very low for all outcomes. For the primary outcome overall symptoms of schizophrenia, results showed a difference favouring CBT without antipsychotics when compared to no specific treatment at long term (> 1 year mean difference measured with the Positive and Negative Syndrome Scale (PANSS MD) -14.77, 95% confidence interval (CI) -27.75 to -1.79, 1 RCT, n = 34). There was no difference between CBT without antipsychotics compared with antipsychotics (up to 12 months PANSS MD 3.38, 95% CI -2.38 to 9.14, 2 RCTs, n = 63) (very low-certainty evidence) or compared with CBT in combination with antipsychotics (up to 12 months standardised mean difference (SMD) 0.30, 95% CI -0.06 to 0.65, 3 RCTs, n = 125). Compared with no specific treatment, CBT without antipsychotics was associated with a reduction in overall symptoms (as described above) and negative symptoms (PANSS negative MD -4.06, 95% CI -7.50 to -0.62, 1 RCT, n = 34) at longer than 12 months. It was also associated with a lower duration of hospital stay (number of days in hospital MD -22.45, 95% CI -28.82 to -16.08, 1 RCT, n = 74) and better functioning (Personal and Social Performance Scale MD -12.42, 95% CI -22.75 to -2.09, 1 RCT, n = 40, low-certainty evidence) at up to 12 months. We did not find a difference between CBT and antipsychotics in any of the investigated outcomes, with the exception of adverse events measured with the Antipsychotic Non-Neurological Side-Effects Rating Scale (ANNSERS) at both 6 and 12 months (MD -4.94, 95% CI -8.60 to -1.28, 2 RCTs, n = 48; MD -6.96, 95% CI -11.55 to -2.37, 2 RCTs, n = 42). CBT without antipsychotics was less effective than CBT combined with antipsychotics in reducing positive symptoms at up to 12 months (SMD 0.40, 95% CI 0.05 to 0.76, 3 RCTs, n = 126). CBT without antipsychotics was associated with a lower number of participants experiencing at least one adverse event in comparison with CBT combined with antipsychotics at up to 12 months (risk ratio 0.36, 95% CI 0.17 to 0.80, 1 RCT, n = 39, low-certainty evidence). This review is the first attempt to systematically synthesise the evidence about CBT delivered without medication to people with schizophrenia. The limited number of studies and low to very low certainty of the evidence prevented any strong conclusions. An important limitation in the available studies was that participants in the CBT without medication group (about 35% on average) received antipsychotic treatment, highlighting the challenges of this approach. Further high-quality RCTs are needed to provide additional data on the feasibility and efficacy of CBT without antipsychotics.

Load and recovery monitoring in Swiss top-level youth soccer players: Exploring the associations of a new web application-based score with recognised load measures

Load and recovery monitoring in Swiss top-level youth soccer players: Exploring the associations of a new web application-based score with recognised load measures

Virtual Quantum Resource Distillation.

Distillation, or purification, is central to the practical use of quantum resources in noisy settings often encountered in quantum communication and computation. Conventionally, distillation requires using some restricted "free" operations to convert a noisy state into one that approximates a desired pure state. Here, we propose to relax this setting by only requiring the approximation of the measurement statistics of a target pure state, which allows for additional classical postprocessing of the measurement outcomes. We show that this extended scenario, which we call "virtual resource distillation," provides considerable advantages over standard notions of distillation, allowing for the purification of noisy states from which no resources can be distilled conventionally. We show that general states can be virtually distilled with a cost (measurement overhead) that is inversely proportional to the amount of existing resource, and we develop methods to efficiently estimate such cost via convex and semidefinite programming, giving several computable bounds. We consider applications to coherence, entanglement, and magic distillation, and an explicit example in quantum teleportation (distributed quantum computing). This work opens a new avenue for investigating generalized ways to manipulate quantum resources.

Intestinal Effects of Filtered Alkalinized Water in Lean and Obese Zucker Rats.

This study evaluated the intestinal effects of alkalinized filtered water in lean and obese adult Zucker rats. For 3 months, 12-week-old rats consumed either tap water or filtered alkalinized tap water from Madrid city. Weight gain was monitored, changes in metabolism were evaluated by indirect calorimetry, and total antioxidant capacity and levels of inflammatory mediators were measured in plasma. Feces were collected, their microbial composition was analyzed and histological analysis of the small and large intestine was performed, assessing the general state of the mucosa (MUC2), the inflammatory state (F4/80) and the presence of oxidative modifications in protein 4-Hydroxynonenal (4-HNE) by immunofluorescence (IF) and immunohistochemistry (IHC). The results obtained showed that the consumption of alkalinized filtered water improved the composition of the intestinal microbiome and the state of the intestinal mucosa, reducing both local and systemic inflammation and the level of oxidative stress. These changes were accompanied by a better maintenance of the oxidative status in rats. No differences were observed in antioxidant capacity nor in weight gain. The incorporation of probiotics in the diet had a significant impact on the microbiome. These effects were indicative of an improvement in general metabolic, oxidative and inflammatory status.

Health-related quality of life of type 2 diabetes mellitus patients: A cross-sectional study in the cape coast metropolis.

Type 2 diabetes mellitus (DM) has in recent decades become a global pandemic, accounting for over 90% of DM cases. The study evaluated the health-related quality of life (HrQoL) and identified its determinants among type 2 DM patients at the University of Cape Coast Hospital. We conducted our study at the University of Cape Coast Hospital from January to March 2022. The EQ-5D-5L questionnaire was administered to 68 type 2 DM patients. Data were then inputted into Microsoft Excel and analyzed accordingly using IBM SPSS statistical software version 26 and GraphPad Prism 8. The mean age of the participants was 60.71 ± 12.18 with 55.9% being females. The average systolic, diastolic blood pressure and fasting blood glucose (FBG) of participants were 140.99 ± 22.27, 85 ± 11.14 and 7.97 ± 2.66 respectively. With the EQ-5D-5L scale, participants reported severe to extreme problems mainly in pain/discomfort (19.1%) and mobility (8.8%) dimensions. Approximately 21% (14/68) of patients reported themselves as being in perfect health based on the EQ-5D index score with no significant difference between males and females (p ≥ 0.05). On a scale of 0 to 100, most (26.5%) of the participants rated their general health state at 80. Age was significantly associated with all five dimensions while patients with comorbidities had higher odds of experiencing pain/discomfort and anxiety/depression. The study reveals that pain/discomfort and anxiety/depression are the most experienced problems among patients with type 2 DM. The HrQoL of type 2 DM patients was also found to be affected by age, comorbidities, systolic and diastolic blood pressure. Therefore, identifying these factors and developing appropriate interventions is crucial for improving patient outcomes and enhancing treatment outcomes.