Information about the last stages of a binary neutron star inspiral and the final merger can be extracted from quasi-equilibrium configurations and dynamical evolutions. In this article, we construct quasi-equilibrium configurations for different spins, eccentricities, mass ratios, compactnesses, and equations of state. For this purpose we employ the SGRID code, which allows us to construct such data in previously inaccessible regions of the parameter space. In particular, we consider spinning neutron stars in isolation and in binary systems; we incorporate new methods to produce highly eccentric and eccentricity reduced data; we present the possibility of computing data for significantly unequal-mass binaries; and we create equal-mass binaries with individual compactness up to 0.23. As a proof of principle, we explore the dynamical evolution of three new configurations. First, we simulate a $q=2.06$ mass ratio which is the highest mass ratio for a binary neutron star evolved in numerical relativity to date. We find that mass transfer from the companion star sets in a few revolutions before merger and a rest mass of $\sim10^{-2}M_\odot$ is transferred between the two stars. This configuration also ejects a large amount of material during merger, imparting a substantial kick to the remnant. Second, we simulate the first merger of a precessing binary neutron star. We present the dominant modes of the gravitational waves for the precessing simulation, where a clear imprint of the precession is visible in the (2,1) mode. Finally, we quantify the effect of an eccentricity reduction procedure on the gravitational waveform. The procedure improves the waveform quality and should be employed in future precision studies, but also other errors, notably truncation errors, need to be reduced in order for the improvement due to eccentricity reduction to be effective. [abridged]