General Principles Of Management Research Articles

Pyoderma Gangrenosum: A Challenging Cutaneous Manifestation in Dubowitz Syndrome.

Pyoderma gangrenosum (PG) is a challenging cutaneous manifestation associated with Dubowitz syndrome, a rare genetic disorder characterized by multiple congenital anomalies, developmental delay, and distinctive facial features. This review article aims to provide a comprehensive overview of the association between Dubowitz syndrome and pyoderma gangrenosum, emphasizing the clinical presentation, challenges in diagnosis and management, and potential underlying mechanisms. A comprehensive literature search was conducted to gather relevant studies, and inclusion and exclusion criteria were applied to select appropriate articles. The association between Dubowitz syndrome and pyoderma gangrenosum has been documented in reported cases and studies. Clinical characteristics of Pyoderma gangrenosum in Dubowitz syndrome include painful necrotic ulcers with undermined borders. Diagnosing pyoderma gangrenosum in the context of Dubowitz syndrome can be challenging due to the overlapping clinical features and complexities associated with the syndrome. Managing pyoderma gangrenosum involves a multidisciplinary approach, with general principles of wound care, systemic therapy, and pain management. Specific considerations for treating pyoderma gangrenosum in Dubowitz syndrome include collaboration among specialists and careful monitoring. Future directions for management include further research to understand the underlying mechanisms and develop targeted therapies. Recognizing and addressing pyoderma gangrenosum in Dubowitz syndrome is crucial for optimal patient care. This review enhances awareness among healthcare professionals and provides insights for improving diagnosis, management, and treatment outcomes for individuals with this challenging combination of conditions.

The Effects of Patient Characteristics on the Management of Subclinical Hypothyroidism: A Survey of Faculty and Trainees

ObjectiveThere is no universal approach to the management of subclinical hypothyroidism (SCH). This study was designed to determine the impact of patient characteristics on management decisions in SCH amongst physician faculty members and trainees. MethodsAn online survey was distributed to faculty members and medical trainees (ie, interns, residents, and fellows) at multiple academic medical centers. The survey included 9 clinical scenarios describing women with SCH with 5 management options sequenced from most “conservative” (no further treatment or monitoring) to most “aggressive” (treatment with levothyroxine). ResultsOf the 194 survey respondents, 95 (49.0%) were faculty members and 99 (51.0%) were trainees. Faculty members were more likely to report being “confident” or “very confident” in making the diagnosis of SCH compared to trainees (95.8% vs 46.5%, P < .001). Faculty members were also more likely to consider patient preference for treatment (60.0% vs 32.3%, P < .001). Among all respondents, the clinical factors that resulted in the highest predicted probability of treatment were hypothyroid symptoms (predicted probability [PP] 68.8%, 95% CI [65.7%-71.9%]), thyroid stimulating hormone >10 mIU/L in a 31-year-old (PP 63.9%, 95% CI [60.3%-67.3%]), and the desire for fertility (PP 52.2%, 95% CI [48.6%-56.0%]). In general, faculty members favored more aggressive treatment across all clinical scenarios. ConclusionThe presence of symptoms, thyroid stimulating hormone >10 mIU/L, and desire for fertility were most predictive of the decision to treat in SCH. In several clinical scenarios, both trainee and faculty decision-making demonstrated discordance with general SCH management principles.

How We Would Treat Our Own Lung Transplantation: A Multidisciplinary and International Perspective

Lung transplantation is the ultimate treatment for end-stage lung disease (ESLD) arising from various etiologies. This manuscript will focus on selected aspects of a theoretical perioperative lung transplantation plan, highlighting data-driven and theoretical techniques the authors would employ if they were the index patient undergoing surgery. Beginning with looking for a transplant center using an Internet search, patient advocacy organizations, and artificial intelligence guidance, the authors lay out a course for multidisciplinary care throughout the entire patient journey, ending with ideal approaches to recovery 6 months posttransplantation. Although the index case will focus on a theoretical patient with pulmonary fibrosis, the general management principles will be applicable across the entire spectrum of patients with ESLD presenting for lung transplantation.

Synthèse des principes et schémas de prise en charge dans les troubles neurologiques fonctionnels

After more than twenty years of academic research on functional neurological disorders (FND) throughout the world, a standardized care management strategy has emerged to allow a more adapted care offer to patients with FND, as close as possible to their experience and their needs. With regard to this special issue on FND in collaboration with L’Encéphale and at the initiative of the Neuropsychiatry section of the AFPBN (French Association of Biological Psychiatry and Neuropsychopharmacology), we would like to suggest a summary of all topics discussed in more detail in each article of this special issue, in order to facilitate its reading. We therefore cover the following themes: the initial contact with a patient with FND, the diagnostic process in favor of a positive diagnosis, the physiological, neural and psychological basis of FND, the diagnostic announcement (and its intangibles), the therapeutic patient education in FND, the general principles of therapeutic management through a personalized and multidisciplinary care program, and the validated therapeutic tools available according to the symptoms identified. This article is designed to be of broad interest on FND, supported by tables and figures showing the key points of all these steps, to keep an educational purpose at most. We hope that through this special issue, each health professional will be able to grasp this knowledge and this framework of care as easily and quickly as possible, in order to participate in the standardization of the care offer.

Emergency management of patients with Glanzmann thrombasthenia: consensus recommendations from the French reference center for inherited platelet disorders

Glanzmann thrombasthenia (GT) is a genetic bleeding disorder characterised by severely reduced/absent platelet aggregation in response to multiple physiological agonists. The severity of bleeding in GT varies markedly, as does the emergency situations and complications encountered in patients. A number of emergency situations may occur in the context of GT, including spontaneous or provoked bleeding, such as surgery or childbirth. While general management principles apply in each of these settings, specific considerations are essential for the management of GT to avoid escalating minor bleeding events. These recommendations have been developed from a literature review and consensus from experts of the French Network for Inherited Platelet Disorders, the French Society of Emergency Medicine, representatives of patients’ associations, and Orphanet to aid decision making and optimise clinical care by non-GT expert health professionals who encounter emergency situations in patients with GT.

The Determination of State Budget Governance of Indonesian Public Higher Education Institutions Post COVID-19 Pandemic

The communication and information openness era, which has become increasingly massive after the COVID-19 Pandemic, has encouraged open relations between the community and state universities in education programs, especially budget management. This study aims to analyze the determination of state university budget management in terms of budget realization, the role of technology, and public information disclosure. This study raises the dimensions of the variable position of technology, perceptions of budget realization, public information disclosure, principles of general financial management, transparency, and accountability concerning managing state finances in universities. Convenience sampling became the technique chosen for sampling and was further analyzed with the SEM-PLS procedure through the SmartPLS application with 237 respondents. This study found the effect of budget realization and public information disclosure in fulfilling the principles of positive public financial management. However, this study does not support the role of technology in supporting the principles of public financial management. This study also notes the positive influence of public financial management principles on state universities' transparency and accountability. This study highlights the maximum future strengthening of higher education budget management with the organizational commitment of higher education institutions under the strict supervision of the government and the community indirectly. Technology does not support it, but it impacts the public in tracing information on Higher Education budget management according to the mandate of various parties, including the Indonesian Supreme Audit Institution.

Immune-related adverse events secondary to immunotherapy in oncology: A guide for general practice.

Immunotherapy has reshaped the prognoses for many cancers and is increasingly used in both metastatic andadjuvant settings. There is a high prevalence of immunotherapy side effects, or immune-related adverse events (irAEs), which can affect any organ. Some irAEs can cause permanent or prolonged morbidity and, in rare cases, may be fatal. irAEs can present with mild, non-specific symptoms, resulting in delays to identification and management. We aim to provide a general overview of immunotherapy and irAEs, highlighting common clinical scenarios and general principles of management. Cancer immunotherapy toxicity is an important clinical problem that is increasingly relevant to general practice, where patients with adverse events may first present. Early diagnosis and timely intervention are important in limiting the severity and morbidity of these toxicities. The management of irAEs should follow treatment guidelines, in consultation with patients' treating oncology teams.

Approach to dealing with acute heart failure in cats and dogs

Background: Unfortunately, heart disease is common in both dogs and cats and may eventually result in congestive heart failure (CHF). However, the clinical signs of CHF overlap with other causes of respiratory compromise. As such, differentiating cardiac from non‐cardiac causes of respiratory distress is a common diagnostic challenge in emergency veterinary practice. The general principles of heart failure management can be applied to a broad range of cardiac diseases; identifying a cardiac cause for the clinical signs is therefore more important than making a definitive diagnosis in the acute phase of heart failure. Nevertheless, there is no ‘one‐size‐fits‐all’ recipe for treatment and the approach needs to be tailored to the individual (eg, severity of clinical signs, comorbidities, patient demeanour and so on). Although the information in this article is organised linearly, the approach to an emergency case seldom follows the structure used in more stable patients. For example, a dog or cat presenting with significant dyspnoea will typically require treatment (eg, supplementary oxygen ± light sedation) before physical examination and diagnostic testing, and some diagnostic tests may need to be postponed until the patient is stable enough to safely undergo them; therefore, the initial treatment plan is often based on a working, rather than a definitive, diagnosis.Aim of the article: This article provides an overview of the diagnosis and management of acute heart failure, highlighting similarities and differences between dogs and cats. The aim is to help practitioners approach these cases with more confidence.

THE STUDY OF THE MANAGEMENT OF THE QUALITY OF EDUCATION IN INSTITUTIONS OF GENERAL SECONDARY EDUCATION: HISTORICAL ASPECT

Research relevance is caused by the fact that education is realized as an educational service and the quality of education is studied as an accordance to educational standards and personal demands. The aim of the article is to justify and bring to life philosophical-pedagogical aspects of education management formation in Ukraine and in the world. It was found out that all aspects of education management development are important, however in regards with our research quality is seen as: a) Absolute notion – it is a standard; b) Relative meaning – it is means of defining the appropriateness of the standard result; c) Category which is the complex of object’s qualities and corresponds the requires, demands and norms. Different approaches to defining education quality were analyzed, namely with the help of studying pedagogical-philosophical works of various scientists. Philosophical-pedagogical aspects of education quality management in secondary education institutions were revealed. It was emphasized that employees’ activity on the base of principles of general quality management facilitates constant increase of education quality, approving objective managing decisions, interest of every participant of the process and responsibility for the result. It was found out the education quality management at present is considered as a continuous process of interaction of managing and managed systems, aimed at providing availability of qualitative nursery, primary, basic and secondary education in the educational system due to creating the conditions of functioning and development of general educational system.

Surgical treatment for facial nerve involvement in salivary gland tumor

The most important consideration in performing a parotidectomy is to accurately identify the facial nerve and preserve its function. There are various descriptions of the location and branching types of the facial nerve trunk. During parotid surgery, knowledge about the incidence and prognostic aspects of facial nerve involvement caused by parotid tumors is necessary. The extent of dissection and the method of anatomical tissue separation will be determined not only by anatomical variations of the facial nerve, but also by the size and location of the tumor Invasion of the facial nerve in parotid malignancies is one of the most significant factors affecting prognosis, which may require radical parotidectomy for proper treatment. Surgical resection remains the mainstay of treatment for cancer of the parotid gland, and there is general agreement that facial nerve should not be sacrificed unless the tumor is adherent to, or surrounds the nerve. The following statement describes general principles of troublesome management of the facial nerve during surgery for parotid tumor.

Evaluating the Conditions of Crisis Management of Industries and Problems of Health, Safety, and Environment Staff in Confronting Coronavirus Disease 2019: A Qualitative Study in Qom Province

Background &amp; Aims: Crisis refers to events or situations that suddenly occur due to natural and human accidents and functions and impose difficulties and problems on a human collection. Crisis management enables an organization to eliminate some of the crises, such as coronavirus disease 2019 (COVID-19), manage some others efficiently, and acquire the required tools for rapid and thorough learning from the occurred crises. The present study aimed to evaluate the conditions of crisis management of industries and problems of health, safety, and environment (HSE) staff in confronting COVID-19 in Qom province. Materials and Methods: The present research is a qualitative study based on content analysis. The participants included 23 staff working at the HSE center of industries that entered the study through a random convenient method from various industries and organizations. Questions on evaluating the preparedness and response to crisis sections were designed and completed. The data were analyzed using MAXQDA V10 software. Results: The analysis of the data regarding investigated companies indicated that 21 companies (91.3%) were privately owned, and two companies (8.7%) were semi-private. Regarding the field of activity, the companies were also active in 9 groups. The mean number of staff in the investigated companies and the mean number of HSE staff were 154.48 and 1.48 people, respectively. The content analysis clarified that only in 11 investigated collections (47.83%) had the managers noticed it before identifying COVID-19. Providing disinfectants and personal protective equipment was the most critical problem in confronting COVID-19. Simplification of the disease and non-compliance with the instructions by staff were also placed in the next rank. Conclusion: According to the results of the present study, the conditions of preparedness and response to the COVID-19 crisis were not of the desired status in the investigated collections. Increasing the number of staff in the HSE center and applying the general principles of crisis management, especially planning and taking a lesson from past crises, can help increase the level of preparedness of organizations and industries for probable future crises.

ENVIRONMENTAL MANAGEMENT OF THE USE OF NATURAL RESOURCES IN THE SUSTAINABLE DEVELOPMENT OF THE NATIONAL ECONOMY OF UZBEKISTAN

One of the most important tasks facing the general principles of environmental management, and one of the most important tasks facing our country, is to ensure its socio-economic efficiency. Therefore, the widespread development of the environmental management system is becoming important in the socio-economic development of our country in the coming years. The aim of this study is also to create ecological mills for management, as well as environmental management, which will be used to achieve economic stability.

Management of Eight Hand Drill Nails Induced Penetrating Brain Injury

Abstract Background Penetrating brain injury (PBI) can be caused by several objects ranging from knives to chopsticks. However, an assault with hand drill while working in a factory is a peculiar accident. Because of its rarity and lack of standard protocol management, the management of PBI is complex. Case Presentation We presented a case of a 26-year-old male with alleged history of insertion of eight nails from a hand drill machine from right side of head while working in a factory accompanied by loss of consciousness and history of vomiting. Computer tomography demonstrated that nails passed through the right parietal bone and reached up to contralateral hemisphere and posterior cranial fossa. Removal of nails and hematoma evacuation was done timely that led the patient to have a good postoperative recovery. Conclusion In this case report, we discussed the successful management of a very rare penetrating head injury with a hand drill machine. The goal of this case report is to demonstrate the general management principles in PBI that can improve the patient outcome.

КОНЦЕПТУАЛЬНЫЕ ПОЛОЖЕНИЯ ПО УПРАВЛЕНИЮ ВЫСОКОТЕХНОЛОГИЧЕСКИМИ КЛАСТЕРАМИ НА ОСНОВЕ СЕТЕВОГО РАЗВИТИЯ

The article defines the purpose and reveals the main conceptual provisions for the management of high-tech clusters based on network development. The characteristics of the object, the subject and the scientific foundations of cluster management are given. The purpose and generalized economic, managerial, technological, social, environmental and information management tasks are considered. The general principles of management are outlined, as well as criteria and indicators for evaluating the results of managing high-tech clusters. The author’s position regarding methods, technologies and processes of cluster information support is indicated. An understanding of the cluster management mechanism based on network development is proposed.

ДЕЯКІ АСПЕКТИ УПРАВЛІННЯ РОЗВИТКОМ ЛЮДСЬКОГО КАПІТАЛУ

The article considers the key aspects of the formation and development of human capital. The approaches are analyzed and the definition of human capital as a socio-economic category is formulated. The factors of formation, development and management of human capital are determined. Effective state management of the development of human capital requires the definition of conceptual foundations for improving theoretical and methodological tools. The theoretical and methodological foundations of the formation and development of human capital are formulated on the basis of dialectics, systematicity, the law of the general development of the system and the forms of its manifestation. Methodological patterns of formation and development of human capital are formed. The classification of the human capital structure was carried out in accordance with the formation of the general principles of human capital management and investment principles. The structure of human capital is classified according to the following characteristics: by constituent elements, by types of goods, by levels of management, by temporary changes, by subjects of management and investment. It is proved that the management of the development and investment of human capital is based on its elemental structure with the allocation of a system of private, collective and public goods and the differentiation of components with a time characteristic of the activity of use. The component approach to the formation of the structure of human capital determined the consideration of the following elements: capitalized contribution to the development of future generations, physiological, entrepreneurial, intellectual, social capital, transactional effect, effects of corporate rights and public goods. An improved concept of the «knowledge-based society» based on the proposal to introduce an additional component of institutionalization with the components «labor», «capital», «institutions». The foundations and factors of the formation and development of human capital, the mechanism of functioning of human capital in the economic system are studied in detail.

ЄВРОПЕЙСЬКІ ТА МІЖНАРОДНІ ПІДХОДИ ДО УПРАВЛІННЯ ЯКІСТЮ В ОСВІТІ З ВИКОРИСТАННЯМ ІНТЕЛЕКТУАЛЬНИХ ТЕХНОЛОГІЙ

The article compares the international and European requirements for institutions of higher education. General international principles of quality management were also considered and adapted to institutions of higher education. The main requirements for the quality management system (QMS) of a higher education institution (HEI) following international and European standards,) as well as the advantages and main requirements for the implementation of the quality management of educational services, as a tool for managing the processes of providing educational services and improving their quality.

Management of an impacted maxillary central incisor with surgical exposure and a 2x4 orthodontic appliance: A case Report

Dental impaction or transposition are disorders related to ectopic eruption or failure in tooth eruption, which can affect child physical, mental, and social development. This condition compromises face aesthetics, phonation, and masticatory function. The cause of impaction may vary from physical obstruction in the path of eruption, tooth material arch length discrepancy to malformation of the tooth, but supernumerary teeth are the leading cause. Failure of eruption of maxillary incisors requires early diagnosis and proper treatment planning. General principles of management of the condition include removal of physical obstruction, creation of space, and surgical exposure with or without traction. The rationale of the 2x4 orthodontic treatment of an unerupted tooth depends upon its age, position, etiology, and amount of space in the dental arch. It under the category of interceptive orthodontic procedure to prevent malocclusion near future. The present case report elaborates on case of incisor impaction with different aetiologies and varying ranges of complexity. However, it's far frequently important to continue with a surgical–orthodontic treatment. The inclination of teeth in relation to the midline and the root maturation degree determine prognosis and therapeutic timing. Thus, we are describing a case of 10 yrs. old child with, class 1 molar relationship bilaterally with missing maxillary right central incisor.

Post-COVID-19 Respiratory Management: Expert Panel Report

This report is the first expert panel report on the management of post-COVID-19 patients from India The report contains high risk groups, post-COVID-19 patient management at primary care level, general principles of medical management of post-COVID-19 in primary care settings, management of post-COVID-19 symptoms in primary care settings, recommendations for inclusion and exclusion into the Pulmonary Rehabilitation Programme, post-COVID-19 patient management at tertiary care level, post-COVID-19 complete assessment and management, and respiratory disease-specific conditions requiring expert opinion and further research

Understanding the approach to animals with thermal burns

Thermal burn injuries represent a spectrum of superficial to deep epidermal and dermal injury sustained after exposure to a liquid, solid or gaseous heat source. Severe thermal burns result in both local damage and systemic effects. In systemically compromised animals, managing major body system abnormalities takes priority over surgically managing the thermal burn. General principles of wound management are relevant to animals with thermal burns. The surgical approach will vary according to individual wound and patient factors. Adjunctive therapies, such as negative pressure wound therapy, are touched on. Further research into thermal burns in veterinary cases is warranted.

8954 Abdominal Wall Nerve Blocks

<h3>Study Objective</h3> To demonstrate the nerve block techniques for the ilioinguinal, iliohypogastric, lateral femoral cutaneous, and the genital branch of the genitofemoral nerves. <h3>Design</h3> Procedural video. <h3>Setting</h3> Operating room at an academic medical center. <h3>Patients or Participants</h3> Patients with chronic abdominal pain. <h3>Interventions</h3> This video demonstrates how to perform nerve blocks to the ilioinguinal, iliohypogastric, lateral femoral cutaneous, and genital branch of the genitofemoral nerves. It also highlights the techniques of these nerve blocks and includes general management and follow-up principles for these patients. <h3>Measurements and Main Results</h3> Patients' individual responses to nerve blocks are assessed on a pain scale of 0-10. They are measured prior to and after nerve blocks to gauge response. <h3>Conclusion</h3> Determining the source of chronic abdominal and pelvic pain can be difficult for gynecologists. Nerve blocks can be an effective strategy to help evaluate and possibly treat abdominal wall pain. These blocks can delineate whether pain is originating from the abdominal wall or from another source. Nerve blocks can also potentially be therapeutic in instances of nerve entrapment, muscle spasms, neuralgia, or myofascial pain. These instructional videos on administering abdominal nerve blocks can help gynecologists provide another potential source of therapy for their patients.