Semi-global bipartite fault-tolerant containment control framework on antagonistic communication networks is proposed in this article for heterogeneous multiagent systems (MASs) under the influence of input saturation and actuator faults. An observer is constructed to estimate the leaders' states on signed digraph, where the communication networks are antagonistic. A fully distributed virtual control approach is developed to acquire the containment trajectory. Based on the observer, a semi-global containment control method is developed to compensate for the detrimental impacts of both input saturation and actuator faults. Besides, the dynamics and state-space dimensions of the agents can be different. The proposed framework overcomes two drawbacks of the conventional containment control: 1) the containment trajectory is obtained under general antagonistic communication networks, which is more general in engineering applications and 2) both actuator faults and input saturation are solved for heterogeneous agents, which relaxes the limitation of homogeneous dynamics. Finally, a simulation example is conducted to test and verify the feasibility of the proposed method framework.