The expansion of the construction of cottage villages, isolated settlements in ecologically clean areas, away from large cities, as well as the provision of gas to the settlements of the eastern part of the Russian Federation, sets the task of developing autonomous gas supply systems. A significant deterrent to the development of autonomous gas supply systems based on butane mixtures with air is their high cost and the absence of scientifically sound recommendations for choosing system parameters. To develop scientifically sound recommendations for the design of systems, considering all the factors of influence that ensure the optimal cost of gasification and subsequent maintenance by the consumer, additional studies are necessary. The article considers the choice of optimal centralization of gas supply systems based on a mixture of butane with air to determine the minimum cost of construction and operation for consumers. the systems analysis, mathematic model methods with calculation of optimal values in the presence of corresponding limits and the methods of material correlation processing are used. The data have been obtained for effective centralization of gas supply systems based on butane-air mixture. The criteria are set which influence the optimum number of houses connected to a tank installation, such as population density in a gas supplied area, climatic features of an area, a type of consumer’s gas-using equipment and a form of settlement development. As a result of the research, the optimum number of apartments has been determined for gas supply to a settlement connected to a tank installation. These recommendations will make it possible to increase efficiency of gas supply source selection and consumer connecting to a gas sup-ply network at minimum cost for consumers