ABSTRACTUrban populations are increasingly exposed to excessive heat. Heat distribution in the urban environment can be affected by several factors, including the spatial arrangement of land use/land cover (LULC) that is specific to a given city. This study applies a climate model with urban canopy parameterisation to downscale future climate projections and simulate the spatio‐temporal pattern of heat in the urban environment to better understand the effect of LULC structure on its distribution. Heat conditions are characterised by climate indices that are well representative in two mid‐sized Central European cities of Brno and Ostrava (Czech Republic). Our results show that the annual number of hot days (HOT), summer days (SUD), tropical nights (TRN) and warm nights (WAN) will increase significantly (p < 0.01) in the 21st century in both cities. The model also simulates a more intensive increase and a higher spatio‐temporal variability in all indices in Brno compared to Ostrava. In Brno, the annual number of HOT and TRN is projected to be more than 500% of the 1981–2010 reference period's value by the end of the 21st century under the RCP 8.5 scenario. To determine the causes of the differences in heat distribution, we applied LULC configuration metrics and correlation analysis using various geographical factors. The higher risk of urban heat in Brno compared to Ostrava can be attributed to a more homogenised and less fragmented LULC structure and to the more substantial role of altitude in the complex terrain of Brno. Other factors, such as the presence of impervious surfaces and vegetation, have a similar effect on the variability of the studied indices in both cities. Urban planners should consider the role of the LULC structure and the changes that can be made in a city when designing adaptation measures to mitigate the effects of urban heat.