The article deals with the problem of differentiation and scientific research of scientific knowledge in chemistry at the university. The strategic foundations of science and education incorporation in modern society are presented, together with the main objectives and tasks to enhance their collaboration. The combination of science and education on the foundation of universities has been formed as a multifaceted process, involving the construction of a global data environment, a unified educational space, and the employment of various new teaching methods.One of the research disciplines of chemistry at the university was chosen as a model for studying the mechanisms of integration and differentiation. The relational integration of various fields of knowledge and scientific research in chemistry is considered in detail. The paper exposes the issues that initiate the procedure of combining pedagogical education with science; reveals the areas of work of the department that contribute to the development of scientific research and interaction of the educational process; proposes new fundamental and comprehensive professional skills required for the construction of upcoming bachelors and masters of pedagogical education ready for an innovative combination of knowledge and scientific activity centered around the exploration of the field;educational and analyzed ways to improve the effectiveness of the pedagogical university in the integration of research works are proposed.The purpose of the article is to offer an opportunity to study chemical theories, to develop knowledge and scientific and theoretical knowledge of universities.