Intelligent separation is a core technology in the transformation, upgradation, and high-quality development of coal. Realising the intelligent recognition and accurate classification of coal flotation froth is a key technology of intelligent separation. At present, the coal flotation process relies on artificial recognition of froth features for adjusting the reagent dosage. However, owing to the low accuracy and subjectivity of artificial recognition, some problems arise, such as reagent wastage and unqualified product quality. Thus, this paper proposes a new froth image classification method based on the maximal-relevance-minimal-redundancy (MR MR)-semi-supervised Gaussian mixture model (SSGMM) hybrid model for recognition of reagent dosage condition in the coal flotation process. First, the features of morphology, colour, and texture are extracted, and the optimal froth image features are screened out using the maximal-relevance-minimal-redundancy (MRMR) feature selection algorithm based on class information. Second, the traditional GMM clusterer is improved, called SSGMM, by introducing a small number of marked samples, the traditional GMM’ problems of unclear training goals, invisible clustering results, and artificially judged clustering results are solved. Then a new hybrid classification model is proposed by combining the MRMR with the modified GMM (SSGMM) which can be named as (MRMR - SSGMM). The optimal froth image features are screened by MRMR to provide the SSGMM classifier. In the process of training and learning the feature samples, using the marked feature samples of froth images to guide the unmarked feature samples. The information of marked feature samples of froth images is mapped to the unmarked feature samples, the classification of the froth images were realised. Finally, the accuracy of the SSGMM classifier is used as the evaluation criterion for the screened features by MRMR. By automatically executing the entire learning process to find the best number of froth image features and the optimal image features, so that the classifier achieves the maximum classification accuracy. Experimental results show that the proposed classification method achieves the best results in accuracy and time, compared with other benchmark classification methods. Application results show that the method can provide reliable guidance for the adjustment of the reagent dosage, realize the accurate and timely control of the reagent dosage, reduce the consumption of the reagent and the incidence of production accidents, and stabilize the product quality in the coal flotation production process.