Frequency Of Various Types Research Articles

Analysis of the frequency of cervical pathology manifestation in permanent teeth of different groups

Cervical tooth lesions today belong to the most common dental pathologies characterized by a pronounced tendency to increase. The aim of our study was to determine the frequency of various types of cervical pathology in formed permanent teeth. Material and methods. The randomized group of examined patients included 200 middle-aged individuals (100 males and 100 females). The examination included collecting anamnestic data and examining the oral cavity and teeth to identify cervical caries and non-carious lesions of cervical localization. Results. Various types of cervical tooth pathology were found in 45 % of the total number of examined patients. The highest percentage among cervical lesions belongs to cervical caries (28.5 %). The frequency of cervical erosions is 16 %, and wedge-shaped defects - 13.5 %. Cervical caries and erosions are more often detected in males, while wedge-shaped defects are more common in females. In females, isolated cervical caries are most frequently manifested (36 %), and isolated wedge-shaped defects and erosions are less frequent (16 % and 17 % respectively). The least frequent manifestation in females is the combined lesion of teeth with wedge-shaped defects and erosions (5 %). In males, isolated cervical caries is most frequently detected (42 %), isolated erosions are nearly twice less common (23 %), and isolated wedge-shaped defects (8 %) and combined lesions of teeth with wedge-shaped defects and erosions (4 %) are the least frequent. All types of cervical pathology most often affect premolars, less often incisors, and least often molars. Conclusions. 45 % of middle-aged individuals seeking dental care have cervical tooth lesions, with the highest percentage being cervical caries. Cervical caries and erosions are more common in males, while wedge-shaped defects are more common in females. All types of cervical pathology most often affect premolars and, least often, molars

A GRU-Based Model for Detecting Common Accidents of Construction Workers.

Fall accidents in the construction industry have been studied over several decades and identified as a common hazard and the leading cause of fatalities. Inertial sensors have recently been used to detect accidents of workers in construction sites, such as falls or trips. IMU-based systems for detecting fall-related accidents have been developed and have yielded satisfactory accuracy in laboratory settings. Nevertheless, the existing systems fail to uphold consistent accuracy and produce a significant number of false alarms when deployed in real-world settings, primarily due to the intricate nature of the working environments and the behaviors of the workers. In this research, the authors redesign the aforementioned laboratory experiment to target situations that are prone to false alarms based on the feedback obtained from workers in real construction sites. In addition, a new algorithm based on recurrent neural networks was developed to reduce the frequencies of various types of false alarms. The proposed model outperforms the existing benchmark model (i.e., hierarchical threshold model) with higher sensitivities and fewer false alarms in detecting stumble (100% sensitivity vs. 40%) and fall (95% sensitivity vs. 65%) events. However, the model did not outperform the hierarchical model in detecting coma events in terms of sensitivity (70% vs. 100%), but it did generate fewer false alarms (5 false alarms vs. 13).

Characteristics of eating behavior in obese children, living in the Moscow region

Obesity is one of the most pressing problems of modern pediatrics. An important role in its formation is played by an eating disorder (ED). Рurpose. Analysis of the frequency of various types of ED in obese children living in the Moscow region, depending on age and gender. Materials and methods. 150 children with exogenous constitutional obesity (SDS BMI≥+2.0) were examined, 87 of them boys (58%) and 63 girls (42%). Two age groups were identified: group I - age 8-12 years (73 children), group II - age 13-17 years (77 children). The assessment of the NPP was carried out using the Dutch DEBQ eating behavior questionnaire. Results. 89% of the respondents had registered ED. An isolated restrictive type of ED was more often detected (39%), less often a combination of all three types (23%) and a combination of restrictive and emotionogenic types (11%). Monovariants were more often registered in children of group I, and a combination of all three types of ED was more often registered in group II. Regardless of age and gender, the restrictive type prevailed among the monovariants. In children of group I of the combinations, a combination of restrictive and emotionogenic types was more often noted, in children of group II - all three types. Different combinations of the two types were more often registered in girls, whereas of all three types - in boys. Conclusion. ED was registered in the absolute majority of the surveyed obese children living in the Moscow region, regardless of age and gender (89%). The predominance of the restrictive type of ED indicates irrational attempts to control body weight through diet. An increase in the frequency of detection of a combination of all three types in adolescence, mainly in males, indicates a high risk of the possibility of ED transition to psychiatric disorders in this category of patients. It is necessary to use questionnaires in clinical practice for the timely detection of ED in children and correction of therapeutic and preventive measures.

Lysosomal storage diseases. Sphingolipidoses — gangliosidoses

Epidemiology, clinical, biochemical and molecular genetic characteristics of gangliosidoses, genetically heterogeneous group of autosomal recessive diseases caused by hereditary deficiency of lysosomal glycohydrolases involved in the catabolism of GM1-, GM2- and GA2-gangliosides, are presented. Three clinical forms of GM1 gangliosidosis are caused by hereditary deficiency of lysosomal β-galactosidase, one of the activities of which is the release of galactose from carbohydrate complexes. As a result, GM1-ganglioside and, to a lesser extent, keratan sulfate accumulate in the lysosomes of neurons and other cells. Three genetically heterogeneous forms of GM2-gangliosidosis are associated with dysfunction of hexosaminidase activity. Tay–Sachs disease, or GM2 ganglioside variant B, is caused by mutations in the hexosaminidase alpha chain HEXA gene. Sandhoff’s disease is associated with mutations in the HEXB gene for the hexosaminidase beta chain. In this case, there is a deficiency of the A and B components of the enzyme — the null variant of GM2 gangliosidosis. In variant AB, or juvenile GM2 gangliosidosis, all hexosaminidase components are present, but the activating factor is defective due to mutations in the GM2A gene. All types of gangliosidosis are characterized by progressive retardation of psychomotor development and early death of patients, most often under the age of 3 years. The frequency of various types of gangliosidoses in different populations does not exceed 1 : 300,000. An exception is the ethic group of Ashkenazi Jews, in which the incidence of Tay–Sachs disease, reaches 1 : 3000, which makes total screening of heterozygotes and prenatal diagnosis of the disease in high-risk families economically justified. The article highlights the importance of experimental models for studying the molecular basis of pathogenesis and developing various therapeutic approaches, such as bone marrow transplantation, enzyme replacement therapy and substrate reducing therapy, gene therapy, and genome editing. Clinical examples of patients with gangliosidosis are given to improve the efficiency of diagnostics of these rare diseases by clinicians.

СОСТОЯНИЕ СЕРДЕЧНО-СОСУДИСТОЙ СИСТЕМЫ У НОВОРОЖДЕННЫХ, РОЖДЕННЫХ ОТ МАТЕРЕЙ, ПЕРЕНЕСШИХ ВО ВРЕМЯ БЕРЕМЕННОСТИ НОВУЮ КОРОНАВИРУСНУЮ ИНФЕКЦИЮ

Cardiac manifestations in the acute phase and complications of COVID-19 in children, especially newborns, have not been sufficiently studied as yet. The purpose of this research was to determine the nature of damage to the cardiovascular system (CVS) in newborns from mothers who had a new coronavirus infection at different stages of pregnancy and who were infected after birth. Materials and methods used: a single-center observational comparative study with elements of retrospective analysis. The 3 groups of full-term newborns of 37 each were formed as follows: the main group 1 (A) of newborns from mothers who had a laboratory-confirmed new coronavirus infection in the 1st to 2nd trimesters of pregnancy; the comparison group 2 (B) of newborns with a laboratory-confirmed new coronavirus infection from mothers who had COVID-19 in the peripartum period; and the control group 3 (C) of practically healthy newborns. The frequency of various types of CVS lesions (myocarditis, rhythm and conduction disorders, perinatal CVS lesions) as well as the frequency of occurrence of signs of electrophysiological myocardial instability, hemodynamic disorders and increased levels of cardiac-specific enzymes were assessed. Results: newborns from mothers who suffered a new coronavirus infection during pregnancy are more likely than newborns from physiologically healthy pregnancy and childbirth to develop cardiac problems (heart failure (p=0.025), cardiac arrhythmias (p<0.001), specified congenital anomalies of the cardiac septum (p1-3<0.001), other specified congenital heart anomalies (p1-3=0.032) and other cardiovascular disorders that arose in the perinatal period (p<0.001)), in particular, maladaptive disorders of the cardiovascular system with signs of electrical instability of the myocardium, dilation of the heart cavities and increased levels of cardiac-specific enzymes, which required the exclusion of myocarditis. Conclusion: the identified changes in the cardiovascular system dictate the need for monitoring of newborns from mothers with COVID-19 with dynamic CVS assessment.

Workplace Violence and its contributing factors in healthcare workers of Peshawar Khyber Pakhtunkhwa Pakistan

Objective: To find the frequency of various types of violence and its contributing factors among healthcare workers in tertiary healthcare hospitals of Peshawar. Study Design: Cross-sectional study. Place and Duration: Emergency Department, Khyber Teaching Hospital Peshawar, Peshawar, from 1st January 2021 to June 30, 2021. Methodology: A sample size of 400 healthcare professionals from three hospitals was determined using open epi simple size calculator. The selection of participants was conducted using a non-probability convenient sampling approach. Data was collected using a pretested structured questionnaire after the participants' informed permission was acquired. Healthcare professionals include individuals such as physicians and registered nurses. Results: Most healthcare employees, 97.5%, said they did not experience physical abuse. A total of 1.5% of participants reported experiencing being assaulted once, whereas 1.0% reported experiencing physical assault two to three times. The mean and standard deviation for the latter group were calculated to be 1.04±0.232. A total of 37.2% of respondents said they did not experience any verbal abuse during the previous year. A total of 14.8% of respondents reported experiencing verbal harassment at least once, while 31.8% indicated facing verbal abuse two to three times. Additionally, 16.2% reported encountering verbal abuse more than four times during the last year. These findings yielded a mean of 2.27 occurrences of verbal abuse, with a standard deviation of 1.127. Conclusion: Verbal abuse is a pervasive concern in healthcare, often coupled with physical and emotional aggression. Keywords: Aggression, Abuse, Physical Violence, Psychological Violence, Health Care Providers, Medical Staff. How to Cite This: Jan k, Gul R, Khalil KR, Hassan F, Hameed N, Hamid R. Workplace Violence and its contributing factors in healthcare workers of Peshawar Khyber Pakhtunkhwa Pakistan. Isra Med J. 2023; 15(1): 15-19. DOI: https://doi.org/10.55282/imj.oa1369 This is an Open Access article distributed under the terms of the Creative Commons Attribution-Noncommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

The Hearing Impaired Child- Pattern of Tympanograms in Otitis Media with Effusion

Background: Otitis media with effusion (OME) is a common cause of treatable hearing loss in children. Tympanometry is an objective tool for assessment of this condition. Of the various tympanometric curves, Type B flat curve is commonly associated with OME. The study aims to determine the various curves associated with OME and find the commonest one.Objective: To determine the frequency of various types of curves obtained on tympanogram in children suffering from otitis media with effusion.Material and Methods: This descriptive cross sectional study involving 350 ears with OME was conducted in ENT Department of Medical Teaching Institution, Hayatabad Medical Complex, Peshawar. Non-probability convenience sampling technique was used to select children with OME.History, Clinical examination, otoscopy, audiometry and tympanometry were used to diagnose OME. Tympanometry was performed to determine the type of curves using Jerger classification. The frequency of the various types of curves obtained was calculated.Results: The age range of the patient was 3-15 years with mean age of 8.25±3.22 years. The male: female ratio was of 1.22:1. Type B curves were the commonest inall age groups. The overall frequency for Type B curve in the study was 81.4%. Chi square test showed that Type B tympanogram significantly occurred in the lower age groups ranging from 3 to 11 years.Conclusion: Type B tympanogram is the commonest type of curve in children suffering from otitis media with effusion. It is significantly associated with OME in the younger age groups as compared to Type C & Type A. Therefore it can be used for in the diagnosis and follow-up of younger children with OME.Keywords: Audiometry, Glue, Otitis Media with Effusion, Paediatrics, Tympanometry.

Associations between social activities and depressive symptoms in adolescents and young adults with autism spectrum disorder: Testing the indirect effects of loneliness.

Previous studies have found that social activities and depressive symptoms in adolescents and young adults with autism spectrum disorder are related. To better understand the relationship between these issues, this study examined the frequency of various types of social activities as well as if the participants felt that the frequency of time spent in the activity met their personal needs. In addition, the role of loneliness was tested as a possible way to understand the relationship between activities and depressive symptoms. To test these ideas, 321 participants who were recruited from the Simons Foundation Powering Autism Research for Knowledge (SPARK) research match registry and completed online measures of social activities, depressive symptoms, and loneliness. While the specific pattern was different for individual activities, it was found that those who felt that their current frequency of activities did not meet their needs had higher rates of depressive symptoms than those who felt they did meet their needs. Also, loneliness helps to understand relationship between social activities and depressive symptoms. The findings were discussed in light of previous study findings, interpersonal theories of depression, and clinical implications.

Fractures of the Proximal End of the Femur: Exploration of Treatments and Assessment of Outcomes

ABSTRACT Fractures of the proximal extremity of the femur are some of the most common injuries treated by orthopedic surgeons, often associated with life-threatening polytrauma. Trochanteric fractures have an increased incidence, which is becoming more common due to the aging population. Femoral neck fractures are a particular type of intracapsular hip fracture, and the location of the junction makes the femoral neck prone to fracture. Fractures of the femoral shaft are found in approximately 6-9% of cases of femoral neck fractures. The management of these fractures is interdisciplinary, but in most cases, it requires surgical treatment to allow rapid elevation and recovery of autonomy. The present study is retrospective in which 140 cases of fracture of the upper femur extremity collected at the trauma department of Naousa and Kilkis Hospital over 4 years from December 2018 to December 2022 were analyzed, processed, and reviewed with a minimum follow-up of 6 months. The purpose of this article is to analyze the frequency of various types of fractures of the proximal extremity of the femur and to identify the etiological factors that contribute to these injuries, thus providing a comprehensive understanding of these traumatic events to treat them. The study showed that there is a preponderance of trochanteric fractures, with an increased frequency in the 75-89 age group and a predominance of femoral neck fractures in women, mainly caused by falls. External surgical approaches, standard gamma nail, and bipolar treatment had "excellent/good" functional results reflecting the success of the surgical interventions. The high frequency of anatomical reductions underlines the attention paid to the quality of the procedures.

Research on Feature Extraction of Meteorological Disaster Emergency Response Capability Based on an RNN Autoencoder

Climate change has increased the frequency of various types of meteorological disasters in recent years. Finding the primary factors that limit the emergency response capability of meteorological disasters through the evaluation of that capability and proposing corresponding improvement measures in order to increase that capability is of great practical importance. The evaluation of meteorological disaster emergency response capability still has some issues. The majority of research methods use qualitative analysis, which makes it challenging to deal with fuzzy factors, leading to conclusions that are subjective and insufficiently rigorous. The evaluation models themselves are also complex and challenging to simulate and analyze, making it challenging to promote and use them in practice. Deep learning techniques have made it easier to collect and process large amounts of data, which has opened new avenues for advancement in the emergency management of weather-related disasters. In this paper, we suggest a Recurrent Neural Network (RNN)-based dynamic capability feature extraction method. The process of evaluation content determination and index selection is used to build a meteorological disaster emergency response capability evaluation index system before an encoder, based on the encoder–decoder architecture, is built for dynamic feature extraction. The RNN autoencoder deep learning ability dynamic rating method used in this paper has been shown through a series of experiments to be able to not only efficiently extract ability features from time series data and reduce the dimensionality of ability features, but also to reduce the focus of the ability evaluation model on simple and abnormal samples, concentrate the model learning on difficult samples, and have a higher accuracy. As a result, it is more suitable for the problem situation at evaluation of the disaster capability.

The Prevalence, Classification, and Potential Clinical Implications of Anatomical Variations of First Cervical Vertebra

Background: First cervical vertebra has different anatomical features than other cervical vertebrae. It holds globe of skull and lacks body and spine. It is composed of 2 lateral masses linked by anterior and posterior arches. Posterior atlanto-occipital membrane is attached to posterior arch whose lateral edge sometimes ossifies thus converting groove into canal. Consequently, neurovascular groove gets converted into a bony ring “ponticulus posticus”. It can cause of neck pain and headache. Knowledge of this variation is important during various orthopedic procedures involving atlas including C1 lateral mass screw placement. Congenital defects of atlantal arch a developmental failure of chondrogenesis is a rare anomaly. These defects are a benign variation discovered incidentally. Detection of these anomalies is clinically important as they can cause acute neurologic deficits, which is associated with neck extension. Study was done: To determine the prevalence of Ponticulus Posticus and to report the frequency of various types of congenital malformations of the atlantal arch. Methodology: 250 computerized tomography (CT) head and neck in axial and sagittal sections from Picture Archiving and Communication System (PACS) of Dr RMLIMS, Lucknow was studied as CT is the best method to study the bony landmarks and any anomaly. Prevalence of variations was calculated. Data was analyzed statistically using SPSS version 21 by Chi-square test. Result: Prevalence of ponticulus posticus was 32.4%. Males had higher prevalence (20.4%) than females (12%). Incomplete ponticulus posticus (24.4%) was more than complete variant (8%). There was predominance of left sided ponticulus posticus(12% vs 8.4%) Deficient posterior arch was found in 9(3.6%) cases. 6 were of type A 3 were of type B. Conclusion: This study will help in determining cause of neurological deficit in patients due to presence of above variations.

MODERN TRENDS OF CHANGES IN THE MICROBIOTA OF UROGENITAL SYSTEM IN PATIENTS WITH UROLITHIASIS.

Aim: Analysis of trends in the microbial communities of the genitourinary system in patients with urolithiasis. Materials and Methods: 165 urine samples from patients with urolithiasis was examined. The quantitative isolation of microflora was carried out using the bacteriological method. Microorganisms were identified using API biochemical test systems (bioMerieux, France). The percentage of the various types of microorganisms was determined. The reliability of differences in the frequency of various types of microorganisms isolation in a monoculture and the composition of microbial associations was determined by two-field tables with Fisher's Exact criterion. The GraphPad Prism 7 software was used. Results: 198 bacterial cultures of various types were isolated. In one case, a Candida culture was isolated. E. faecalis was the most frequently isolated culture (29.1% of the isolated strains number); E. coli (18.1% of the total number of isolated cultures; K. pneumoniae (11.1%). There were no significant differences in the rate of E. faecalis compared to E. coli. K. pneumonia was isolated significantly less frequently than E. faecalis. These types of microorganisms were also leaders in the formation of bacterial mixes. In addition, these species are involved in the urease activity of bacteria (directly or indirectly), which contributes to the formation of stones in the genitourinary system. Conclusions: E. faecalis is the species most often isolated from patients with purulent-inflammatory processes in patients with urolithiasis, both in the case of mono-infection and as part of mixed bacterial cultures.

FREQUENCY OF VARIOUS TYPES OF DENTOALVEOLAR INJURIES IN TRAUMA PATIENTS VISITING TO TERIARY CARE HOSPITAL

Objectives: To determine the frequency of various types of dento alveolar injuries in traumapatients.Materials and Methods: A Descriptive, Cross Sectional study was conducted at the departmentof Oral and maxillofacial surgery, Hayatabad Medical Complex, Peshawar from 30th July 2021to 30th January 2022. A total of 198 patients were observed in the study. Non probability, consecutive sampling technique was applied.Results: Mean age was 45.6 Years ± 1.92. fourth decade had been the commonest one. Genderwise distribution among 198 patients were analyzed as n= male was 64 (32.3%) and female was134 (67.7%). Distribution of Enamel Infarction among 198 patients were analyzed as n=Yes was47 (23,7%) and No was 151(76.3%). Distribution of enamel fracture among 198 patients wereanalyzed as n= Yes was 45 (22.7%) and No was 153 (77.3%). Distribution of Enamel and Dentinfracture among 198 patients were analyzed as n= Yes was 50(25.3%) and No was 148 (74.7%).Intrusion of tooth into alveolar socket wall among 198 patients were analyzed as n=Yes was 69(34.8%) and No was 129(65.2%)

Evaluation of Different Types of Gallstones Extracted by Endoscopic Retrograde Cholangiopancreatography

Objective: To study frequency of various types of gall stones extracted from bile duct using ERCP Study design: This is a cross sectional study Study place and duration: Study was conducted in the department of Gastroenterology Sir Ganga Ram Hospital Lahore. Study was completed in six months duration from January 2022 to June 2022. Materials and methods: Diagnosed cases of bile duct stones were underwent ERCP and extracted stones were analyzed to determine their composition. Ages of the patients were 20-70 years. Cases of either gender irrespective of residential area were included in this study. Patients with ischemic heart disease, asthma, liver cirrhosis, malignancy, tuberculosis, chronic obstructive pulmonary disease, interstitial lung disease and pregnancy were excluded from the study. During ERCP gross findings of the stones were noted. Results: Total 140 cases were studied having bile duct stones including 55(39.3%) male and 85(60.7%) females. There were 80(57%) cases with the age ≤50 years and 60(42.9%) cases above 50 years. Mean age of the patients was 46 ± 4.72 years. 58(41.4%) cases were from rural area and 82(58.6%) from urban area. Diabetes, hypertension and obesity was found in 38(27%), 47(33.6%) and 49(35%) cases respectively. Cholesterol stones were found in 51(36.4%), mixed stones in 70(50%) and brown pigmented stones in 19(13.6%) cases. Conclusion: Mixed cholesterol gall stones were most commonly found followed by pure cholesterol and brown pigmented stones. Keywords: Gallstones, Bile duct stones, ERCP, Endocscopy, Cholesterol stones,

Breast cancer and prevention perspectives: A public health challenge, Buea regional hospital, Cameroon

With 2.100.000 cases annually, breast cancer (BC) is the most common gynecological cancer globally; 627.000 of those cases result in death yearly. In the next 20 years, it is anticipated that there will be 14.000.000 cases annually and 8.200.000 fatalities. There are numerous histological subtypes of BC. The various cancers include invasive ductal carcinoma, papilloma, medullary carcinoma, phyllode tumors, ductal carcinoma in situ, lobular carcinoma in situ, and Paget disease. BC is a huge public health concern because of the steadily rising cases in our low-resource environments, thus raising the stakes to develop effective screening and early detection programs to reduce morbidity and mortality. Breast ultrasonography and clinical examination appear to hold promise for screening campaigns. Methodology: On the one hand, a descriptive retrospective analysis was conducted based on the pathology laboratory registry of the regional hospital in Buea, Cameroon. The time frame was from March 4, 2016, through May 25, 2019. On the other hand, we appreciate the rising number of women who attended BC screening programs from 2020 to 2022. BC was screened via clinical breast examination and breast ultrasonography before biopsy for confirmation. Results: In terms of frequency, the following precancerous lesions and cancers were recorded: invasive breast carcinoma, carcinoma in situ, papilloma, inflammatory carcinoma, phyllode tumours, and angiosarcoma. Their respective percentages were; 74.84, 14, 47, 6.92, 1.89, 1.57, and 0.32. The number of women who came for BC screening increased steadily from 123 in 2020 to 266 in 2021 and 552 in 2022. All with positive biopsy results first underwent a clinical examination. In the presence of any suspicious signs, an ultrasound investigation was ordered. A biopsy was requested in case of any image suspicious of BC. Response to the cancer screening campaigns in Buea has increased markedly since the project's initiation. Conclusion: Breast cancer is a heterogeneous malignancy made of various histological types. Our study identified the following pathologies in order of frequency: invasive breast carcinoma, ductal carcinoma in situ, papilloma, inflammatory carcinoma, phyllode tumours, and angiosarcoma. As awareness grows as years go by, there is a huge public health challenge. For mass screening, Clinical examination of the breasts and breast ultrasound seems to be the way forward in prevention, as recommended by many clinical trials and WHO. Objectives: The study aimed to determine the frequency of various types of breast cancer and find a good grassroots approach to BC screening in low-resource settings like ours.

Orofacial and facial pain during the new coronavirus infection (COVID-19) pandemic. Choosing a non-steroid anti-inflammator – focus on nimesulide

Doctors of various specialties face orofacial and facial pain in their practice: dentists, maxillofacial surgeons, neurologists, neurosurgeons, otorhinolaryngologists, therapists, general practitioners, traumatologists, ophthalmologists, psychotherapists, physiotherapists, aesthetic medicine doctors, anesthesiologists, plastic surgeons and other specialists. The novel coronavirus infection (COVID-19) pandemic, spread by the SARS-CoV-2 virus, has become a challenge for all medical specialties and health care systems around the world. The respiratory system is the dominant target of SARS-CoV-2. The oral mucosa is also highly susceptible to SARS-CoV-2 infection, due to the wide distribution of angiotensin-converting enzyme type II receptors in the oral cavity. We searched the literature for the period from the beginning of the pandemic until August 22, 2022, on the study of the association of orofacial pain with a new coronavirus infection COVID-19 in the electronic search engines PubMed and Scopus. Analysis of the found sources indicates an increase in the frequency of various types of orofacial pain associated with 1) violation of dentoalveolar and related structures during the COVID-19 pandemic; 2) temporomandibular disorders; 3) with damage or disease of the cranial nerves; and 4) like manifestations of primary headache. This growth is due both directly to the infection caused by SARS-CoV-2, its complications, and to a complex of biopsychosocial factors directly related to the pandemic. In the second part of the article, as part of the review, the possibility of using nimesulide for the treatment of orofacial and facial pain during the COVID-19 pandemic is discussed. The choice of nimesulide is supported by 1) the likely coadjuvant effect of nimesulide in the treatment of COVID-19; 2) positive experience with the use of nimesulide in the treatment of facial and orofacial pain in the period preceding the COVID-19 pandemic; 3) the safety of using nimesulide in comorbid patients, who are the main risk group for the development and severe course of COVID-19.

Exercise Rehabilitation Training in Patients With Pulmonary Hypertension: A Review.

Pulmonary hypertension (PH) has a high morbidity and mortality. Despite the existing disease-targeted therapy, most patients with PH continue to suffer from difficulty in breathing, exercise intolerance, and reduced quality of life. Recently, a large body of research results has suggested that exercise rehabilitation training (ERT) seems to be a beneficial, safe, and cost-effective treatment for patients with PH. However, knowledge gaps still exist for a uniformly accepted ERT protocol, the modality, duration, intensity, and frequency of ERT in PH. The purpose of this review is to summarise the existing research evidence and knowledge, aiming to strengthen clinicians' awareness of the application of ERT in patients with PH. PubMed databases were systematically searched for eligible studies. Twelve (12) randomised controlled trials and other important studies documenting effectiveness, safety, and adverse events of ERT are summarised. Additionally, the modality, duration, intensity, and frequency of various types of ERT and future research directions are discussed. In summary, ERT is generally effective and safe for PH patients as an adjuvant treatment to disease-specific therapy. It can improve the exercise capacity and tolerance, skeletal and respiratory muscle performance, cardiopulmonary function, and quality of life of PH patients. In view of the occurrence of a small number of adverse events, we currently recommend a combination of in-hospital and home-based ERT under close supervision. In the future, more multi-centre randomised controlled studies are needed to evaluate the effectiveness and feasibility of long-term, community, or home-based ERT, as well as to explore the molecular mechanism behind it.

Rheoreaction in Danio rerio (Cyprinidae): Influence of Flow Velocity and Availability of Still Water Zones

The results of an experimental study of the influence of the flow velocity on the rheoreaction indices of Danio rerio, rheopreferendum and the ratio of the frequencies of various types of rheoreaction, are presented. At a crucial for fish flow velocity of 0.30, their rheopreferendum is positive, while at 0.80, negative. The ratio of rheoreaction types at these velocity levels was typical for resident fish. At a crucial flow velocity of 0.45, the rheopreferendum was not expressed, and the fish behavior was typical for upstream-migrating individuals. A decrease in the accessibility of the limnozone (limitation of the zone’s entrance width) in the circular tank reduces the number of fish returning to it and changes the ratio of their rheoreaction types. At the maximum width of the entrance (19 cm), the ratio of zebrafish rheoreaction types reflects the behavior characteristic of migrating individuals, while for all other variants (10, 3, and 1 cm) it is typical for resident forms. It is shown that the rheopreferendum is a less complete and reliable assessment of rheoreaction than the ratio of rheoreaction types. The applicability of rheoreaction indicators is considered.

Genitive definitions in the chronicle of Worms (XVI century)

The article is devoted to the essential issue of the historical stylistics of German the development of the "nominal" or "substantive" style in the Early Upper German period (XIV-XVII centuries). The research was based on the chronicle of Worms (XVI century) that represents one of the most popular genres of the period. The purpose of article is to analyze the topology and frequency of various types of genitive definitions of a noun in the text. We distributed nuclear nouns into seven semantic groups with a total number of examples of about 160.
 The results obtained allow making following conclusions. The prepositive genitive prevails only in the groups of Nomina agentis and relational names. The connection between semantics and the topology of the genitive is hard to trace. Thus, the genitives of subject, object and possessive genitive are distributed between the pre- and postposition almost equally, with some preponderance of the latter. Genitivus definitivus and partitivus tend to postposition. With regards to parameters under consideration, the Worms chronicle corresponds to the general tendency in the XVI century, that is, to move genitive definitions into postposition.

Between-Reporter Agreement Among Couples: Exploring Nonlinear Patterns in Marital Conflict.

This study compares self-reported and spouse-reported frequencies of various types of behaviors couples use in marital conflict using data from Turkish Family Structure Survey (2016), which included 9,636 couples. Existing literature reported low levels of agreement among couples. These studies measured between-reporter agreement levels among couples with linear models which report cumulative scores. However, we hypothesized that low levels of agreement reported in the literature might be due to nonlinear patterns in the self-reported and spouse-reported frequencies. To detect such nonlinear patterns, we compared self-reported and spouse-reported frequencies for each level (frequency) of using the types of conflict behavior styles we investigated. This allowed us to explore the patterns of agreement or disagreement at the low, medium, or high levels of using these conflict style behaviors. Findings of this study confirmed our hypothesizes. There are meaningful nonlinear patterns that are not detectable with cumulative comparative scores. There are also differences in these patterns across the types of conflict behaviors we looked at. For example, the nonlinear patterns we observed for aggressive conflict behavior types are different from the patterns for passive conflict behavior types. We also found that these patterns are different for husbands and wives. This paper highlights the limited capacity of linear models for exploring between-reporter agreement levels and it calls for the consideration of using nonlinear methods for these types of systematic investigation. The major limitation is the lack of analysis on the effect of sociodemographic factors on the observed discrepancies other than gender.