The purpose of this paper is to study the mixed Dirichlet‐Neumann boundary value problem for the semilinear Darcy‐Forchheimer‐Brinkman system in Lp‐based Besov spaces on a bounded Lipschitz domain in , with p in a neighborhood of 2. This system is obtained by adding the semilinear term |u|u to the linear Brinkman equation. First, we provide some results about equivalence between the Gagliardo and nontangential traces, as well as between the weak canonical conormal derivatives and the nontangential conormal derivatives. Various mapping and invertibility properties of some integral operators of potential theory for the linear Brinkman system, and well‐posedness results for the Dirichlet and Neumann problems in Lp‐based Besov spaces on bounded Lipschitz domains in (n≥3) are also presented. Then, using integral potential operators, we show the well‐posedness in L2‐based Sobolev spaces for the mixed problem of Dirichlet‐Neumann type for the linear Brinkman system on a bounded Lipschitz domain in (n≥3). Further, by using some stability results of Fredholm and invertibility properties and exploring invertibility of the associated Neumann‐to‐Dirichlet operator, we extend the well‐posedness property to some Lp‐based Sobolev spaces. Next, we use the well‐posedness result in the linear case combined with a fixed point theorem to show the existence and uniqueness for a mixed boundary value problem of Dirichlet and Neumann type for the semilinear Darcy‐Forchheimer‐Brinkman system in Lp‐based Besov spaces, with p∈(2−ε,2+ε) and some parameter ε>0.