Fourth Position Research Articles

Synthesis, characterization, crystal structure and catalytic activity of amido azo palladium(II) complex

The newly designed tridentate ligand, 2-((2-aminophenyl)diazenyl)-N-benzylaniline, 1 has been synthesized by the reaction between 2,2′-diaminoazobenzene and benzyl chloride in presence of K2CO3. This ligand was reacted with Na2[PdCl4] in methanol to give the new Pd(II) complex 2. Both the ligand and complex were characterized by usual spectroscopic techniques. Furthermore, the solid-state structure of complex 2 was determined using single crystal X-ray diffraction analysis. It revealed that the ligand binds with Pd(II) in dianionic tridentate (N,N,N) fashion offering distorted square planar geometry where fourth position is occupied by one phosphine ligand. The performance of the Pd(II) phosphine complex as catalyst was evaluated in the homogenous Suzuki and Heck reactions under mild conditions in presence of air and moisture. The Pd(II) complex showed good catalytic activities for the coupling of several aryl halides (iodides and bromides) with phenyl boronic acid and styrene providing excellent yields. After catalytic reactions, the catalyst has been recovered by simple chromatographic separation and reused for next reaction and its activity checked up to three cycles without sufficient loss. The newly designed tridentate ligand, 2-((2-aminophenyl)diazenyl)-N-benzylaniline and its corresponding palladium(II) complex were synthesized and structurally characterized. The neutral palladium(II) amido complex with phosphine as ancillary ligand was formed through two amino proton elimination from ligand precursor. The newly synthesized Palladium(II) complex acts as potential catalyst toward C–C bond formation for a variety of substrate under mild conditions in presence of air and moisture.

An Analysis of the utilization of Gamal Plant (Gliricidia sepium) as a shade for coffee plants

Indonesia is the largest coffee exporter in the world, which is in the fourth position after Brazil, Vietnam and Colombia. However, the productivity of coffee produced from year to year tends to decrease and not optimal. This happens because of many factors, one of which is the type of shade plants used. Inappropriate shade plants affect the growth and productivity of coffee plants. The purpose of this research was to analyze the utilization of Gamal plant (Gliricidia sepium) as a shade for coffee plants. The respondents of this research were 35 coffee farmers in Jember and Banyuwangi regencies. The research variables measured included the types of coffee shade plants, reasons for using shade plants and farmers' knowledge about Gamal plant as a shade for coffee plants. The data collection was carried out using survey, interview and questionnaire. The data collection was done directly with the primary source. The results of this research informed that the shade plants used by coffee farmers were varied, such as banana, lamtoro, coconut tree, Gamal, avocado and sengon trees. Most of the coffee farmers used bananas by 86%, avocados by 65%, and wood by 46% as a shade. They chose the plants because they were easier to maintain, cheap seeds and produced fruit and woods which could be sold. Based on the literature, the most effective shade plants for coffee plants were Gamal plants. However, Gamal plant (Gliricidia sepium) is still not widely used by coffee farmers because the seeds are too expensive and it does not produce fruit that can be sold. The conclusion of this research was that most of the coffee farmers were still unaware and did not use Gamal as a shade plants.

Construction and evaluation of an antibody phage display library targeting heparan sulfate

Heparan sulfate (HS) is a linear polysaccharide with high structural diversity. Different HS epitopes have been detected and localized using single chain variable fragment (scFv) antibodies from a ‘single pot’ phage display library containing a randomized complementarity determining region of the heavy chain (CDR3). In this study, we created a new library containing anti-HS scFvs that all harbor a dp-38 heavy chain segment where the CDR3 region was engineered to contain the XBBXBX heparin binding consensus site (X = any amino acid, B = R, K or H). The library contained ~1.73 × 106 unique antibodies and was biopanned against HS from several sources. The selected antibodies were sequenced and chemically/immunohistologically characterized. A number of 67 anti-HS scFv antibodies were selected, of which 31 contained a XBBXBX CDR3 sequence. There was a clear preference for glycine at the first and proline at the fourth position of the CDR3. The sequence GZZP(R/K)X (Z = R, K or H, but may also contain N, S, or Q) was unusually overrepresented. Selected antibodies reacted with HS/heparin, but not with other glycosaminoglycans. Antibodies reacted differentially with respect to N-, 2-O, or 6-O-desulfated heparin preparations, and showed distinct topologies of HS epitopes in rat kidney sections. The library may be instrumental in the selection of a large pool of HS epitope-specific antibodies, and - since all antibodies differ only in their 6 amino acid CDR region - may be a tool for a rational design of antibodies recognizing specific HS sulfation patterns.

NIR emitting platinum pincer complexes based on the N^N^C ligand containing {benz[4,5]imidazo[1,2-a]pyrazin} aromatic system; synthesis, characterization and photophysical study

In the present work we obtained a series of NIR luminescent platinum(II) complexes with a pincer N^N^C ligand based on the conjugated {benzoimidazo[1,2-a]pyrazine} system with the [Pt(N^N^C)L]n+ structural motif (L = phosphine, alkynyl or pyridine-type ligands). We have also synthesized two complexes with bidentate phosphines that demonstrate different types of coordination: 1) as chelating ligand (in case of 1,2-bis(diphenylphosphino)benzene), that led to de-coordination of pyridine ring of N^N^C ligand and formation of a [Pt(N^C)dppb]+ complex; 2) as a bridging ligand (in case of bis(diphenylphosphino)methane) between two {Pt(N^N^C)} fragments in a dimeric complex of type [{Pt(N^N^C)}2dppm]2+. The complexes obtained were fully characterized using spectroscopic methods, and their ground-state structures and photophysical properties were studied by DFT and TD DFT methods. According to the data obtained the aromatic {benzoimidazo[1,2-a]pyrazine} fragment plays a key role in the photophysics of this type of complexes and the triplet 3LC state located at the N^N^C ligand proved to be the only emissive state in all the complexes prepared. Unexpectedly variations in the nature of the ligands occupying the fourth coordination position in the square-planar structural motif, changes in the mode of the N^N^C ligand coordination and even the Pt-Pt bond formation did not result in significant variations of the emission profile. The photophysical behavior of these complexes has been analyzed using DFT calculations, which are in complete agreement with the experimental data and confirmed that the lowest relaxed triplet configuration responsible for the phosphorescence in the complexes studied is located at the N^N^C ligand.

Enhancement of RSSI-Based Localization Using an Extended Weighted Centroid Method With Virtual Reference Node Information

In this paper, an extended weighted centroid localization (EWCL) method for a received signal strength indicator (RSSI)-based localization system is proposed. In the traditional WCL method, an unknown target position is estimated using the actual position of each reference node and RSSI information collected from each reference node based on the distance between the target and each reference node. The estimation accuracy is significantly increased when more reference nodes are applied in the localization system. In addition, in the traditional WCL method, four reference nodes deployed in a square area are initialized and tested. Such a configuration produces good localization results. By this information, in this work, the EWCL method is developed to estimate a target’s position taking into consideration information from four reference nodes, where only three actual reference nodes are deployed in a real test area. Here, the fourth reference node position as the virtual reference node position is defined, and a new technique involving a guideline solution is developed to estimate the distance between the target and the fourth reference node using distance information from the three actual reference nodes. By our purpose, the hardware cost and the complexity of the experimental setup can be reduced, while the estimation accuracy can be increased. To verify the EWCL method, both theoretical and experimental studies are performed. The theoretical study first demonstrates the EWCL performance without the effect of radio signals. The experimental study using low-cost low-power 2.4 GHz nodes deployed in a semi-outdoor test area reveals more realistic results. The results indicate that the EWCL method significantly outperforms the WCL method in all test cases. The localization error is reduced by 49.151% in the theoretical test. In the experimental test, the localization errors are reduced by 33.708 and 28.351% for scenarios without and with a human presence, respectively.

Speech Act Analysis of Whatsapp Statuses Used by Jordanians

This qualitative study aims at investigating the WhatsApp statuses as used by Jordanians. It also investigates the types of speech acts used in these statuses. For this purpose, the study has collected and analyzed 200 statuses. The population of the study included all English language students of Jadadra University, where the sample of the study included (50) students, representing 20 % of the whole population. The results showed that data were classified into six main topics; religious, social, political, personal, romantic and national. Additionally, five themes emerged from the data, namely, expressive, directive, assertive, commissive and declaration. Expressive speech acts represent (37 %) of the total speech acts types analyzed. The directive took the second place, representing (25%) of the total status update analyzed. The assertive and commisive fall into the third and fourth position representing (23%) and (15%) respectively. The declarative type has the no occurrences representing (0 %) of the analyzed data. Some of the recommendations suggested are that further research needs to be conducted into the speech acts used by Jordanians on different social networking platforms.

The geographic distribution of priority population groups for the elimination of mother-to-child transmission of HIV in South Africa

BackgroundWomen of reproductive age living with HIV (WRLHIV), HIV-positive pregnant women, adolescent girls and young women (AGYW) are key populations for eliminating mother-to-child of HIV (eMTCT) in South Africa. We describe the geographical distribution of WRLHIV, their pregnant counterparts and AGYW for risk-adjusted allocation of eMTCT interventions.MethodsFor the year 2018, we triangulated data from the Thembisa Model with five routine HIV-related and demographic data sources to determine the distribution of WRLHIV (15–49 years) and AGYW (15–24 years) nationally and by province. Data analysed included total population estimates, number of live-births, live-births to HIV-positive women, age-specific HIV prevalence rates, intrauterine (IU)-transmission rates and IU-case rates/100 000 live-births. IU-transmission rates and IU-case rates were calculated from de-duplicated routine HIV test-data for neonates (aged <7days). Data de-duplication was achieved by a patient-linking algorithm that uses probabilistic matching of demographics (name, surname, date of birth), supplemented by manual matching to account for spelling errors.ResultsThere were 58 million people in South Africa in 2018. Females (all ages) constituted 51% of the population. Women of reproductive age constituted 27% and AGYW constituted 8% of the total population. WRLHIV, AGYW living with HIV and HIV-positive pregnant women accounted for 7%, 0.8% and 0.4% of the total population respectively. Gauteng was the most populous province followed by KwaZulu-Natal, with Western Cape and Eastern Cape in third and fourth positions. The distribution of WRLHIV and AGYW followed a similar trend. However, Mpumalanga and Limpopo provinces had higher proportions of WRLHIV and AGYW living with HIV ahead of Western Cape. KwaZulu-Natal had the highest number of live-births to HIV-positive women. The national IU-transmission rate of <1% translated into 241 cases/100 000. While provincial IU-case rates were fairly similar at 179–325, districts IU-case rates varied, ranging from 87–415 cases/100 000 live-births.ConclusionFindings suggest that the need for eMTCT interventions is greatest in Gauteng, KwaZulu-Natal, Western Cape and Eastern Cape. Limpopo and Mpumalanga provinces may require more HIV prevention and family planning services because of high fertility rates, high number of WRLHIV and AGYW living with HIV. eMTCT will require robust viral load monitoring among WRLHIV, pregnant and breastfeeding women. The national laboratory database can provide this service near-real time.

An urban composite development index based on China's five development concepts

Purpose Shandong is a thriving economic centre, being the third largest province by land area in China. It also has the second largest resident population of 99,470,000 and the third largest gross regional domestic product of RMB 6.8tn in 2016. The urbanisation rate of Shandong has been quickly expanding from 45 per cent in 2005 to 58 per cent in 2016. This paper aims to examine the urban development, performance and liveability of 17 Shandong cities through areas such as infrastructure, public services, education and environmental protection. Design/methodology/approach Building upon the theoretical underpinnings of China’s five development concepts – innovation, coordination, green development, opening up and sharing, this paper has constructed the inaugural urban composite development for 17 cities based on 131 indicators across six environments, namely, scale and quality of economic activities, financial capacity, labour market flexibility and economic vibrancy, good governance, effective leadership and social stability, technological advancement and innovation capability, public service standards and quality of life improvement and resource conditions and environmental protection. Findings The empirical results show that Qingdao, Weihai and Yantai perform well in urban development, while the capital city Jinan only rank in the fourth position. Originality/value By identifying the relative strengths and weaknesses of each city based on the perspective of ordinary city dwellers, this paper provides appropriate policy recommendations for policymakers to develop and optimise their economies and urban spaces.

Estudo na literatura indexada na base Scopus sobre acessibilidade na web

Se presenta una visión general de la producción científica internacional sobre la accesibilidad a la web a través de una encuesta sobre las principales áreas de conocimiento que publican acerca del tema dos de los países y universidades que tienen producción internacional relevante; se identifican los principales autores y medios donde éstos publican y se señalan los principales términos adoptados en la investigación realizada por ellos. La metodología empleada es descriptiva con un enfoque cuantitativo-cualitativo que se dividió en dos etapas, a saber: 1) encuesta sobre la producción internacional de accesibilidad en la web utilizando la base de datos Scopus como fuente, y 2) análisis de los principales conceptos. Los resultados mostraron que las principales áreas de conocimiento que producen publicaciones sobre el tema son informática, matemáticas y ciencias sociales. Estados Unidos está a la vanguardia de la producción científica en la materia y destacan España y el Reino Unido, Brasil ocupa el cuarto lugar. Los términos más utilizados son “web”, “accesibilidad” y la unión de las dos palabras “accesibilidad a la web”. Como resultado, se identificaron 2 448 autores diferentes, de los cuales 622 publicaron más de un texto, y se preparó un análisis sobre la coautoría en la red. Se sugiere que otros estudios utilicen un enfoque cualitativo que permita un mayor análisis de los conceptos principales e identifique cuáles son los más utilizados y verifique eventuales diferencias de comprensión sobre la temática.

NSC 18725, a Pyrazole Derivative Inhibits Growth of Intracellular Mycobacterium tuberculosis by Induction of Autophagy.

The increasing incident rates of drug-resistant tuberculosis (DR-TB) is a global health concern and has been further complicated by the emergence of extensive and total drug-resistant strains. Identification of new chemical entities which are compatible with first-line TB drugs, possess activity against DR-, and metabolically less active bacteria is required to tackle this epidemic. Here, we have performed phenotypic screening of a small molecule library against Mycobacterium bovis BCG and identified 24 scaffolds that exhibited MIC99 values of at least 2.5 μM. The most potent small molecule identified in our study was a nitroso containing pyrazole derivative, NSC 18725. We observed a significant reduction in viable bacilli load of starved Mycobacterium tuberculosis upon exposure to NSC 18725. The action of NSC 18725 was “synergistic” with isoniazid (INH) and “additive” with other drugs in our checkerboard assays. Structure-activity relationship (SAR) studies of the parent compound revealed that pyrazole derivatives without a functional group at fourth position lacked anti-mycobacterial activity in vitro. The derivative with para-chlorophenyl substitution at the first position of the pyrazole ring was the most active scaffold. We also demonstrate that NSC 18725 is able to induce autophagy in differentiated THP-1 macrophages. The induction of autophagy by NSC 18725 is the major mechanism for the killing of intracellular slow and fast-growing mycobacteria. Taken together, these observations support the identification of NSC 18725 as an antimycobacterial compound, which synergizes with INH, is active against non-replicative mycobacteria and induces autophagy in macrophages.

(E)-4-(((2-amino-5-chlorophenyl)imino)methyl)-5-(hydroxy-methyl)-2-methylpyridin-3-ol and its Cu(II) complex: Synthesis, DFT calculations and AIM analysis

Herein, (E)-4-{[(2-amino-5-chlorophenyl)imino]methyl}-5-(hydroxymethyl)- 2-methylpyridin-3-ol [HL] Schiff base and its [Cu(L)Cl] complex were newly synthesized and characterized by several spectroscopic methods. In addition, density functional theory (DFT) methods were used for investigation of the tautomerization of the HL Schiff base, structural parameters of HL and [Cu(L)Cl] species, assignment of the IR vibrational bands and the NMR chemical shifts as well as natural bond orbital (NBO) analyses. The most stable tautomer of the HL Schiff base is the enol form of the meta isomer. The optimized geometry of the free HL Schiff base is not planar. The L- acts as a N2O tridentate ligand, which is bonded to Cu2+ via the deprotonated phenolic oxygen, and the amine and azomethine nitrogens. The [Cu(L)Cl] has a square planar geometry in which the chloro ligand occupies the fourth coordination position. The DFT-computed values are in good consistency with the corresponding experimental values, confirming the suitability of the optimized geometries for HL and [Cu(L)Cl] species. According to the high-energy gaps, these compounds are stable. The atoms in molecule (AIM) analysis was used to evaluate strength of the bonding interactions and electron densities in structure of the compounds.

P-53 expression in complex and/or atypical endometrial hyperplasia and endometrial adenocarcinoma

Endometrial cancer holds fourth position after breast, colon and lung cancers. In different parts of the world endometrial carcinoma accounts for 4-8% of all cancers. The Age Standardised Rate (ASR) is approximately 4.3 cases per 1,00,000 women. Endometrial cancers are majorly observed in post menopausal women. The age group for diagnosis of endometrial cancers is around 60 years. The most common symptom in patients of endometrial carcinoma is postmenopausal bleeding. The prominent risk factors for endometrial carcinoma include obesity, nulliparity, early menarche and late menopause, and estrogen therapy. There are two types of endometrial cancers: type I endometrial cancer is associated with unopposed estrogen expression and is more common (80% of cases) whereas type II endometrial malignancies are not related to estrogen and are more aggressive tumor.P53-driven model of carcinogenesis is responsible for the rapid development and progression of type II endometrial lesions. Early stage tumors (low grade) are primarily estrogen and progesterone receptor positive and P-53 negative. In contrast the advanced stage tumors (high grade) tumors show strong positive expression for P-53 and are negative for estrogen and progesterone receptors.

Dynamics and determinants of trade exchange between the European Union and India

Purpose – This article attempts to identify and assess trade exchange between the European Union and India, including an indication of the main determinants of the process. Research method – Descriptive analysis based on numerical data from various statistical sources together with a review of specialist literature. Results – Trade exchange between the EU and India is particularly important for India. Exports to the EU account for around 17-20% of Indian exports in total. On the other hand, the EU’s share in Indian imports amounts to 10-12% of all imported goods. Trade with India looks different from the EU side. India’s share in both exports and imports presents a margin for EU trade in goods of 2-3%. The share of services in the trade between the EU and India is high. It accounts for 25-30% of mutual turnover. These are usually modern services based on the offshoring principles, such as IT, business, transport, consulting, science, and tourism. Among the European Union Member States, India’s main trading partners in goods are Germany, the United Kingdom, Belgium, France, the Netherlands, and Italy. These six countries account for ca. 85% of the EU-India trade exchange. In 2007, negotiations started to create an EU-India Free Trade Area. Due to the large differences in the positions of both parties, these discussions were not finalised and were subsequently suspended in 2013. However, after the reactivation of talks in 2016, there is still a possibility for the creation of an EU-India Free Trade Area of 1.8 billion people. Originality /value / implications /recommendations – At the beginning of the 21 st century, in terms of GDP (according to PPP), the European Union (understood as one economic entity) became the second largest economic power globally (after China), while India advanced to fourth position (after China, the EU and the USA). An analysis of trade exchange between these two economic powers allows for a clearer understanding of the modern global economy, as well as the processes and mechanisms of its functioning.

KABAK KEMANE İÇİN POZİSYON DEĞİŞTİRME ÖNERİLERİ

Kabak kemane günümüzde daha çok birinci pozisyonda icra edilen bir çalgıdır ve çalgının ses genişliği en az iki buçuk oktava kadar çıkabiliyor olsa da, özellikle halk müziği örneklerinin icrasında en tiz perdenin oktav La perdesine kadar kullanıldığı görülmektedir. Bu perde, birinci pozisyonda kabak kemanenin birinci teli olan Re telinde 4 numaralı parmakla seslendirilmektedir. Si bemol perdesi oktav La perdesinin hemen altında yer aldığı için bu perdeyi, birinci pozisyonda 4 numaralı parmakla seslendirm ek mümkündür ve zaman zaman bu perdenin bu şekilde basıldığı görülmektedir. Fakat, Si natürel, Sib2, Do ve Re perdelerinin Sib perdesine nazaran daha uzak olmasından dolayı pozisyon değişikliği yapılmadan bu perdeleri basmak imkansızdır. Halk müziği örneklerinde, oktavda yer alan Sİ natürel, Sib2 ve Do perdelerinin yer aldığı eserler ise icracılar tarafından pest taraftan icra edilmektedir. Özellikle çalgısal ve sözlü eserlerde bu tiz perdeler ikinci tel olan La teli üzerinden çalınmaktadır. Bu durum çalgının daha etkin kullanımında bir sorun olarak karşımıza çıkmakta ve bu yüzden gerek icracılara gerekse de konservatuvar öğrencilerine kabak kemanede pozisyon değiştirme alışkanlığı kazandırılamamaktadır. Kabak kemanede farklı pozisyon denemeleri zaman zaman bazı icracılar tarafından yapılıyor olsa da, onlar da her hangi bir halk müziği topluluğu içinde icra yaparken bu perdeleri pest taraftan icra etmektedir. Diğer taraftan kabak kemanede pozisyon değişikliği ile ilgili egzersizlerin veya çalışmaların yer aldığı akademik çalışma bulunmamaktadır. Buradan hareketle bu makalemizde pozisyon değiştirerek, 1. pozisyondan 4. pozisyona geçiş yapılarak tiz tarafta yer alan natürel Si, Sib2, Do ve Re perdelerinin icra edilmesiyle ilgili 12 adet egzersiz önerilmiştir. Bu egzersizlerden sonra da pozisyon değişikliği yapılarak icra edilecek olan bir esere yer verilmiştir. Böylece kabak kemanenin icra seviyesine bir katkı sağlanmaya çalışılmıştır.

The impact of rectal/bladder filling and applicator positioning on in vivo rectal dosimetry in vaginal cuff brachytherapy using an enhanced therapy setting

PurposeThe impact of rectal filling and bladder volume on in vivo rectal dosimetry (IVD) in vaginal cuff brachytherapy (VCBT) is unknown. The purpose of this study was to compare rectal doses from IVD with those calculated from treatment planning and to identify influencing factors. Materials and MethodsWe collected data of 80 VCBT sessions, four for each of 20 patients. Each was retrospectively compared with doses determined by the treatment planning system. Factors potentially predicting the IVD rectum dose were analyzed. ResultsFor a series of 80 brachytherapy applications, the calculated mean dose to the rectum was 2.52 Gy. The mean difference between all calculated and measured doses for the 80 applications with five probe positions each was 0.09 Gy (p = 0.952) proving high overall accordance between IVD and calculated doses at the rectum. The mean volume of the rectum was 119 ± 57 cm³. The rectal volume was not statistically significantly associated with the IVD or the calculated rectum doses. At the third and fourth rectal probe position in craniocaudal ordering, increased filling of the urinary bladder resulted in decreased measured and calculated doses (p < 0.05 for both). A rectum pointing position of the applicator significantly increased the maximum rectum dose compared with a bladder-oriented position (p < 0.05). ConclusionsIVD provided valuable data for rectal exposure in VCBT. Increased bladder filling and vaginal applicator positioning off the rectum elicited related with less rectal radiation exposure, whereas rectal filling did not. Further confirmation including assessment of IVD in bladder is pending to define optimal dosimetric conditions in VCBT.

PENDIDIKAN YANG MEMBEBASKAN MASYARAKAT WAIMITE DARI KEMISKINAN

The reality of poverty is a serious problem for the people in Maluku. Based on the data from the Central Statistics Agency, it shows that Maluku still occupies the fourth position as the poorest province in Indonesia until the first semester of the Periode in March 2018. The phenomenon of poverty here will be researched in the context of poverty experienced by the community in village of Waemite, Kabupaten Buru, Province of Maluku. The community experiences isolation from the development process which results in poverty shackled communities. In addition, one of the practices of local culture ia tutu mo, deadly critical awareness of society. The cultural practice explicitly forbids the people in Waemite for going to school or studying and have higher educational. Education for liberation is a concept of learning to the community both formally (in school education) and informally (religious or community education) aimed at constructing knowledge and critical awareness from and for the community so that it can move a struggle to break the chain of poverty. This research uses a qualitative research method, which explores the ethical and ethical nature of the experience of the poor and various studies related to poverty.

Dentist's Destiny in Disquieting Oral Cancers: An Indian Scenario

Oral cancer is a foremost problem in India where it ranks among the top three types of cancer in the country and is considered an epidemic in recent centuries. Oral cancer is the second most common group of malignancies in males and ranks in the fourth position in females in India. Oral cancers are usually preceded by clinically evident potentially malignant disorders, which can be recognized through oral screening. Early diagnosis and proper management can avert the cancerous potential of the lesion. Although oral cancer rates are alarming, existing situation of dentist in India is devastating. A number of credentials are available in medical literature highlighting the oral cancer rates and problems of dentists in India, but still not much critical steps are taken by the government to improve both situations. Moreover, the oral cavity can reflect and unravel many of the human body's internal ambiguity; in developing country like India, most people do not tend to set the same significance on dental health as they do on their medical health.

Forecasting Design and Principal Dimension Decision in Ship Design Using Parent Design Approach for Folding Boat

In the Nawacita program of the Indonesia President, there is a spirit of accelerating the pace of economic growth in all areas, including tourism. In 2016, national income from the tourism sector rose to the fourth position under oil and gas, coal and palm oil. This program is followed up by areas that have great tourism potential, one of which is East Kalimantan. Most East Kalimantan area based on marine tourism, islands and rivers, it is necessary to create adequate facilities to attract more tourists as well as Bali such as in water sport facilities. One of the most famous water sport is kayaking in Sanur, Kuta, Benoa and others. Seeing the potential of marine tourism in East Kalimantan and the use of kayak already exist in Bali, it is necessary to design a kayak that can be utilized in tourist areas of East Kalimantan. The existing tourist areas in the East Kalimantan region have a long distance and isolated locations that require efficient luggage. Besides, the area has not supported tourism facilities and infrastructure needed by tourists. Therefore, the aim this research is to design a folding boar so that practical to be moved, light and easy for the owner to use it.

Copper (II) Complex of Salicylaldehyde Semicarbazone: Synthesis, Characterization and Antibacterial Activity

Salicylaldehyde semicarbazone ligand and its Cu (II) complex have been synthesized and characterized by a range of physicochemical methods. Experimental data shows the complex is monomeric and the copper atom is four coordinated in a square planar geometry. The ligand chelates the copper in a tridentate fashion through the carbonyl O, imine N, and phenolato O with the fourth position being occupied by coordinated Cl. Antibacterial activity of the prepared compounds was tested against the microbes Enterobacter Aerogenes and Bacillus Cereus. The metal complex showed higher antibacterial activity than the free ligand.

Importance ranking of supplier selection scorecard parameters - among Indian car manufacturing Industry

The Indian automotive industry is now the fastest growing industry in the world ranking at fourth position replacing Germany. For any manufacturing industry, it is not only the customers but suppliers also play a very vital role in success. The proper selection of suppliers is necessary. In this research perception of 40 experts from the car manufacturing industry in India obtained about supplier selection scorecard parameters. The ranking is done based on preference. This ranking is then compared with the ranking of key parameters obtained from the literature survey and Dickson's (1966) ranking. Dickson's study is referred to as the base of research in this area since 1966 by most of the researchers. This research helps - understanding how Indian car manufacturing industry's perceptions are different than global perceptions based on literature survey and Dickson's 23 criteria. It provides the Indian car manufacturing industry's preference rankings for these parameters.