Traditional Medicine Formulation Research Articles

Inventarisasi Tumbuhan Obat Di Desa Golo Ketak Kecamatan Boleng Kabupaten Manggarai Barat, NTT

Indonesia is a country with enormous natural wealth, including a wealth of plant species and a diversity of tribes that have local wisdom in the form of traditional medicine traditions. This study aims to: (1) determine the types of medicinal plants; (2) Knowing the plant organs used for treatment; (3) Knowing the process of processing medicinal plants and how to use the ingredients. The research method used is descriptive method and data collection techniques are carried out through observation, interviews, exploration, collection and documentation. The research data were analyzed descriptively and tabulated in tabular form. The results showed: (1) there were 13 species of medicinal plants in Golo Ketak Village, Boleng District, West Manggarai Regency, (2) parts of the plant organs used to treat the roots/rhizomes/tubers, stems, leaves and fruits; (3) the me thod of processing medicinal plants is by boiling, grating, pounding and smearing Indonesia is a country with enormous natural wealth. This includes the richness of plant species and tribes. Every tribe in Indonesia has local wisdom in the form of traditional medicine. This research is an inventory study of medicinal plants conducted in Gelo Ketak Village, Boleng District, West Manggarai Regency, NTT. This study aims to: (1) determine the types of medicinal plants; (2) Knowing the plant organs used for treatment; (3) Knowing the process of processing medicinal plants and how to use the ingredients. The method used is a descriptive method. Data collection techniques were carried using observation, interviews, exploration, collection and documentation. The research data were analyzed descriptively and made in tabular form. The results showed: (1) there were 13 species of medicinal plants in Golo Ketak Village, Boleng District, West Manggarai Regency, (2) parts of the plant organs used to treat the roots/rhizomes/tubers, stems, leaves and fruits; (3) the method of processing medicinal plants is by boiling, grating, pounding and smearing.

PENGOBATAN TRADISIONAL DI MINANGKABAU

Traditional medicine is a form of treatment method used by people since time immemorial. This knowledge is obtained through human experience and understanding of disease. Traditional medicine is in the form of potions, spells and some are in the form of amulets. Minangkabau society in ancient times also used traditional types of medicine. This can be known through ancient manuscripts found in several places in Minangkabau, such as in Surau, Rumah Gadang, Museum, and Library. This study was conducted to determine the form of traditional medicine in Minangkabau. The analysis was done descriptively. From this research, it is known that in Minangkabau there are several types of traditional medicine that can cure various diseases and even diseases that cannot be cured by hospital medicine can be cured by traditional medicine.

Review on nanogel/emulgel formulations of traditional medicines

Nanotechnology is being ventured into as an emerging trend eliciting improvements in nearly all technological fields, and the pharmaceutical sector is no exception to this. It has been used for many years for synthetic drugs. But nowadays, the focus is on traditional medicines. This work is focused on the nanogel and nanoemulgel formulations of traditional medication and holds strong relevance in the emerging era of nanomedicine. Herbal medicines are making a resurgence in the twenty-first century, as the dangers and limitations of modern medicine become increasingly evident, and herbal remedies are considered a balanced and reasonable approach to treatment. Advances in analysis and clinical research demonstrate the efficacy of herbal drugs in disease prevention and treatment. The main issue with herbal remedies is their inability to dissolve and stabilize. New technical breakthroughs have the potential to eliminate the problems connected with herbal therapy.Nanoformulations reflect the interface between new technology and herboceuticals. Thus nanosized novel drug delivery system of herbal drugs has a potential future due to their high drug encapsulation capacity, homogeneity, low toxicity, and improved stability.

Traditional cauterization among children in Bint Al-Huda Hospital in Al-Nasiriya City, Iraq.

Cutaneous cautery is a form of traditional medicine practiced in many countries. It was mentioned in the books of many ancient, pre-, and post-Islamic scholars. Patients may resort to traditional medicine (cauterization in particular) for many reasons. This study aims is to acquire more knowledge about the cautery practices and the reasons for practicing cautery in children together with other implications from adverse events of the cautery. This is a cross-sectional study in which 133 children were enrolled (77 males and 56 females with age ranged from 0.5 to 108 months) who had been admitted to Bint Al-Huda Maternity and Childhood Teaching Hospital in Nasiriya city, Thi-Qar Governorate, Southern Iraq, from December 1, 2019 to end of July 2020). The study found that >80% of cauterized children were below 1 year, (53.4%) of rural residency. Parents of the cauterized children were mainly of illiterate and primary education constituting the highest percentage (91.6%) of cauterized children were of low per capita monthly income. The grandmothers were advisors in more than half of the cauterized children, a vast majority of the advisors were either illiterate or had primary education, The person performing the cautery was a traditional healer (95.5%). Cauterization was done mostly in the head and abdomen, and a vast majority of it was done by a lighted cotton-tipped application (97%). The number of cauterization points ranged from 2 to 25 with a mean of 8.8 cautery marks. Approximately 59% of patients did not improve or worsened, whereas 30% showed partial improvement, and 11% improved. Complications were seen in 9% of the cases. There is a necessity to spread awareness regarding the dangers and complications of traditional cauterization in health care centers by health care providers. Improving the delivery of medical services to areas far from the city centers as well as spreading health awareness by use of multimedia together with eradicating illiteracy is needed.

COVID-19: an In Silico Analysis on Potential Therapeutic Uses of Trikadu as Immune System Boosters.

Corona virus pandemic outbreak also known as COVID-19 has created an imbalance in this world. Scientists have adopted the use of natural or alternative medicines which are consumed mostly as dietary supplements to boost the immune system as herbal remedies. India is famous for traditional medicinal formulations which includes ‘Trikadu’—a combination of three acrids, namely Zingiber officinale, Piper nigrum and Piper longum which have antioxidant properties that boost our immune system hence acting as a strong preventive measure. In this study, AutoDock 4.0 was used to study interaction between the phytocompounds of Trikadu with RNA-dependent polymerase protein and enveloped protein of the SARS-CoV-2 virus. Analysis of the results showed that coumarin, coumaperine and bisdemethoxycurcumin showed strong bonding interactions with both the proteins. We can conclude that Trikadu has the potential molecules; hence, it can be incorporated in the diet to boost the immune system as a preventive measure against the virus.Supplementary InformationThe online version contains supplementary material available at 10.1007/s12010-021-03793-5.

Accurate medical information recommendation system based on big data analysis

In order to solve the problems of low recommendation accuracy and long response time in traditional medical information recommendation system, a medical information accurate-recommendation system based on big data analysis is proposed. The system is designed as medical information data acquisition module, medical information storage module and medical information accurate-recommendation module. In the medical information data acquisition module, crawler technology is used to obtain medical information data, and association rule algorithm is used to mine the medical information data. In the medical information storage module, personalised configuration is set. In the medical information accurate-recommendation module, the user interest model is quantified by vector space method, and BP algorithm and SOM algorithm are introduced to complete the accuracy of medical information recommend. The experimental results show that: the highest accuracy rate of medical information recommendation is 98.8%, and the shortest retrieval response time is 20 ms.

Gut microbiota and metabolic changes towards improved gut health with supplementation of Woodfordia fruticosa, a medicinal plant: An in vitro study

Woodfordia fruticosa flowers are used as an important component in various fermentation-based traditional medicinal formulations for the treatment of gastrointestinal ailments. In the study, extract of flowers (WfE) was evaluated for its gut microbiota (GM) modulatory properties using in vitro fermentation experiments. WfE supplementation (0.5 and 1 mg/mL) led to significant changes in GM composition by increasing beneficial populations (8–44%) of genus Bifidobacterium, Akkermansia and Lactobacillus while decreasing pathogenic forms (35–91%) such as Bacteroides, Parabacteroides and Alistipes. Functional pathway prediction indicated upregulation of gluco-related metabolism, vitamin production, decrease in insulin resistance and lipopolysaccharide biosynthesis. Metabolomics (1H NMR) revealed significant increase in butyric acid (≥48%) and other SCFAs (17–49%) and glycerylphosphorylcholine (55–85%), with decrease in trimethylamine (4–9%), and trimethylamine oxide (31–38%). Results indicated WfE to be a novel source of functional food ingredient/ supplement and its potential application in an unexplored area of “food phytoceuticals” for maintenance of gut homeostasis. Industrial relevanceMedicinal plants with a long history of use in the treatment of gastrointestinal diseases could be novel sources of functional food ingredients that can have application in gut health. WfE was effective in modifying the gut microbial environment constructively by increasing beneficial microbial populations, suppressing opportunistic pathogenic forms, and also generating key metabolites associated with gut protective functions. WfE has potential industrial application as a functional food ingredient/supplement particularly in decreasing pathogenic populations reported to be involved in manifestation of inflammation, IBD, IBS, and metabolic syndrome.

Determination of Chestnut Honey Consumption Characteristics as a Traditional Treatment Method and Its Effect on Protection from COVID-19

Background: Chestnut honey plays a positive role in strengthening the immune system as it contains vitamins, minerals and antioxidants. It, moreover, has both antibacterial and antiviral properties. Objectives: This study aimed to examine how people consume chestnut honey as a form of traditional medicine and how it might protect them from COVID-19. Methods: This study was carried out on 177 people (who had been snowball sampled) from a province in Turkey where chestnut honey is widely produced. The data was collected using a 20-open/closed-question online questionnaire form that asked the participants to report their sociodemographic details, how they consume chestnut honey, and about COVID-19. Results: 41.8% of the participants reported that they used chestnut honey to protect themselves against COVID-19, 40.7% believed that chestnut honey helped to make them immune against COVID-19, and 37.3% felt that chestnut honey could treat COVID-19. However, there was no significant relationship between the participants consuming chestnut honey and their either being tested for COVID-19 (p > 0.05, χ² = 1.080) or testing positive for COVID-19 (p > 0.05, χ² = 0.793). Conclusions: This study revealed that chestnut honey is a widely used remedy in Turkey for treating different health problems and for maintaining health. In contrast, it also demonstrated that consuming chestnut honey has no effect on protecting the participants from COVID-19.

Mulberry Leaf and Radix Astragali Regulates Differentially Expressed Genes and Proteins in the Streptozotocin-Induced Diabetic Mice Liver

As a chronic non-infectious disease, severely affecting human quality and health of life, diabetes mellitus (DM) and its complications have gradually developed into a major global public health problem. Mulberry Leaf and Radix Astragali have been used as a traditional medicinal formulation in diabetic patients for a long time, whose combination is usually found in traditional Chinese medicine prescriptions. However, due to the unclear synergistic mechanism of them for DM, the changes of differential genes and proteins in the liver tissue of streptozotocin-induced diabetic mice were analyzed, and then the potential synergistic mechanism of them in anti-diabetes was investigated in our research. Compared with the diabetic model group, there were 699 differentially expressed genes and 169 differentially expressed proteins in the Mulberry Leaf and Radix Astragali treated group, and there were 35 common specific genes both in the transcriptome and the proteome. These common genes participated mainly in the pathways, such as retinol metabolism, steroid hormone biosynthesis, and arachidonic acid metabolism. Quantitative real-time PCR() and Western blot results speculated that the synergistic effect on anti-diabetes was mainly through regulating the expression of Tap1, Ncoa4, and Alas2, by down-regulating Fabp2 and Hmox1 and up-regulating Hmgcr, Cyp7a1. All these genes would affect bile acid secretion, alleviate the occurrence of iron death, promote the metabolism and synthesis of glycolipid substances, and ultimately maintain the body’s glucose homeostasis.

A review on: Medicinal properties of ginkgo biloba

Traditional medicine and medicinal plants, as well as their study of modern chemical principles, may lead to the development of newer, less expensive medications. Ginkgo Biloba is well-known for curing a variety of ailments and is utilized in a variety of traditional medicinal formulations. Scientists and researchers from all over the world have spent decades studying the chemical composition of the entire Ginkgo Biloba plant, as well as its biological and pharmacological functions. These investigations established Ginkgo Biloba's medicinal potential in modern medicine and as a prospective drug discovery candidate. The current paper provides an overview of Ginkgo Bilobaethnobotany, phytochemistry, pharmacology, and toxicity.

THE FREQUENCY OF CLINICAL SYMPTOMS OF TONGUE, PULSE AND SYNDROMES ACCORDING TO TRADITIONAL MEDICINE IN ASTHMA PATIENTS

Background: Asthma is a heterogeneous disease, which is usually characterized by chronic airway inflammation. It is a global disease that is not only life - threatening to patients but financial burden to family as well as the society. According to Traditional Medicine, Asthma is related to the scope of wheezing and dyspnea. There is a variety of symptoms and syndromes in this disease. However, the classification of symptoms and clinical forms of traditional medicine from different literature sources is not really the same. Objectives: To survey the frequency of occurrence of the tongue and pulse symptoms, syndromes clinical according to traditional medicine and Determine some factors related to the occurrence of clinical presentation in patients with Asthma. Materials and method: A cross sectional study 102 patients has been diagnosed with asthma and treatment at the Department of General Internal Medicine - Endocrinology, Hue University of Medicine and Pharmacy Hospital and at the Department of Endocrinology - Neurology - Respiratory, Hue Central Hospital from 7/2020 đến 3/2021. Results: The symptoms of the tongue: About the tongue color: 27.5% pale tongue. About the tongue shape: 27.9% enlarged tongue. About the tongue fur: 56.7% white fur; 18.3% dry fur; 41% thick fur. The symptoms of the pulse: 72.1% sunken pulse, About frequency pulse: 25% rapid and a little rapid. The syndromes: lung qi deficiency is dominant in Asthma which accounts for 41.2%, kidney yang deficiency 25.5%, spleen deficiency 3.9%. Conclusion: Symptoms have high rate such as pale red tongue, white fur, moist fur thick fur, moderate pulse, sunken pulse. Symptoms have low rate such as wet fur, exfoliated fur. Lung qi deficiency and kidney yang deficiency have high rate and spleen deficiency have low rate. There were significant relationships between syndromes and tongue color, tongue fur color, and pulse frequency (p < 0.05). Key words: frequency, symptoms of tongue, symptoms of pulse, syndrome, asthma, traditional medicine.

REVIEW ON HERBAL LOZENGES PREPARED FOR COLD AND FLU.

Traditional medicine and herbal formulation have been used by mankind for the care and treatment of various diseases and disorder. Throat infections are most common diseases in today’s world. However it is not taken too seriously by people long term throat infection can lead to severe throat problems pharyngitis and also cancer. The polyherbal lozenges are solid preparation that contains one or more medicaments usually during a flavored, sweetened base that are intended to dissolve or disintegrate slowly within the mouth. The benefits of they medicated lozenges is that they increase a retention time of the dosage form in mouth which increases bioavailability, reduces gastric irritation and bypasses first pass metabolism. 
 Keywords: polyherbal lozenges, pharyngitis

MANAGEMENT OF MENTAL DISORDER PATIENTS (ADHIATMIKA DHUKA) IN BALI PROVINCE HOSPITALITY

<p>This research is focused on the discussion of (1) integration between traditional and conventional medicine in the RSJ (Mental Hospital) of Bali, (2) the form of a combination of traditional medicine with conventional medicine for mental disorder patients at Mental Hospital of Bali, (3) the impact of integrating traditional medicine and conventional in mental patients at Mental Hospital of Bali. The theory used in analyzing the three problem formulations in this study, namely: (1) psychoanalytic theory, (2) ethnomedicine theory, and (3) perception theory. This research uses the method of documentation, literature study, observation and interviews. The results of this study indicate the following points. First, the factors that cause psychiatric rehabilitation patients at RSJ Bali integrate traditional and conventional medicine consisting of internal factors, e.g., beliefs, needs for holistic nursing care, religion, social, and culture, and also external factors, e.g., state legitimacy towards traditional medicine and western biomedical weakness. Second, the form of traditional medicine for mental illness patients at RSJ Bali Province consists of traditional forms, e.g., diagnosis (nengerin), peruwatan (bhuta Yajna) and spells, speech, dharma wacana (spiritual ceremony), prayer, and text-based handling (manuscripts) of medicine and a combination of traditional and modern techniques, and also conventional forms of treatment for psychoanalysis, cognitive behavioral approaches (cognitive behavior), humanistic approaches, and other types of therapy. The form of combining traditional and modern techniques consists of diagnosis, improvement of mental development, the use of drugs, and treatment by spiritual means. Third, traditional and conventional treatments for mental patients at RSJ Bali have an individual impact, social impact, psychological impact on patients, the impact of power, and the impact of community culture.</p>

Inovasi Pemberdayaan Ekonomi Pada UKM Jamu Rumah Herbal Mak Nyak di Kabupaten Jember

The current pandemic condition raises the need to always maintain health and body immunity to be of utmost priority. Herbal medicine as a form of traditional medicine plays an important role in the treatment of population in developing countries, especially Indonesia. The majority of traditional herbal medicine businesses are carried out by home-based business groups, such as traditional herbal medicine businesses carried out by groups of women in Dasa Wisma Aster Dahlia who are domiciled at Tegalbesar Village, Kaliwates District, Jember Regency, produced among others: Jamu Temulawak, Jamu Kunci Sirih, Jamu Kunyit Asem and Jamu Beras Kencur, the herbal medicine which is produced is made from “empon empon” as the base ingredient which is quite abundant in Jember Regency. Herbal medicine business has a very good potential to be developed, because the market demand is very high so that if it is pursued more seriously, it can be used to support the economy of Dama's members. Team acts as: (1) Presenters of socialization, initiator and signing of the MOU document between the two parties, (2) Trainer or assistant for production, monitoring and evaluation (monev) ) post production, packaging and labeling of the final product. Delivering material in the form of lectures, discussions and questions and answers, practice and supervision, continuous monitoring and evaluation to achieve self-sufficiency in production with good product quality. Dama’s members as a socialization participant, also acts as a training participant and mentors the production, marketing, packaging and labeling of the final product.

Traditional, Complementary and Integrative Medicine Approaches to COVID-19: A Narrative Review

Traditional, complementary, and integrative medicine (TCIM) approaches to COVID-19 represent a paradigm shift from Western medicine, in that TCIM emphasizes prevention, encouraging wellness, and supporting health and recovery. A wide range of TCIM approaches exist: whole medical systems (such as traditional Chinese medicine), mind-body approaches, biological therapies, body-based treatments, and energy therapies. TCIM is used to help people resist infection, but people with moderate to severe COVID-19 symptoms often relied on integrative approaches using both traditional and Western medicine. It is estimated that over 90% of the infected population in Hubei China had used some form of traditional medicine to treat COVID. Ayurvedic medicine promotes immune-boosting strategies. Among biologically based therapies, there are vitamin therapies and “immune-nutrition” as well as traditional botanical treatments. Energy therapies have been promoted by the Chinese government to treat COVID-19 which may cause a loss of qi energy and an imbalance with too much yang energy in relation to yin. In many ways, it is difficult to apply Western approaches of clinical trials to TCIM, where most treatments are preventive, restorative, and highly individualized. However, the role of TCIM in COVID-19 was significant and underscores the value of TCIM approaches not just in this pandemic but for other infectious diseases as well. This is a narrative review rather than a systematic review or meta-analysis.

Platelet enhancement by Carica papaya L. leaf fractions in cyclophosphamide induced thrombocytopenic rats is due to elevated expression of CD110 receptor on megakaryocytes

Ethnopharmacological relevanceCarica papaya leaf juice/decoction has been in use in folk medicine in Srilanka, Malaysia and in few parts of India for enhancing the platelet counts in dengue. In Siddha medicine, a traditional form of medicine in India, papaya leaf juice has been used for increasing the platelet counts. Papaya leaf has been reported to enhance blood volume in ancient Ayurveda books in India. Carica papaya leaf is well known for its platelet enhancement activity. Although many preclinical and clinical studies have demonstrated the ability of papaya leaf juice for platelet enhancement, but the underlying mechanisms are still unclear. Aim of the studyThe study is aimed at identifying the key ingredients of papaya leaf extract and elucidate the mechanism (s) of action of the identified potent component in mitigating thrombocytopenia (Thp). Materials and methodsC. papaya leaf juice was subjected for sequential fractionation to identify the anti-thrombocytopenic phytochemicals. In vivo, stable thrombocytopenia was induced by subcutaneous injection of 70 mg/kg cyclophosphamide (Cyp). After induction, rats were treated with 200 and 400 mg/kg body weight papaya leaf juice and with identified fractions for 14 days. Serum thrombopoietin level was estimated using ELISA. CD110/cMpl, a receptor for thrombopoietin on platelets was measured by western blotting. ResultsAdministration of cyclophosphamide for 6 days induced thrombocytopenia (210.4 ± 14.2 × 103 cells/μL) in rats. Treating thrombocytopenic rats with papaya leaf juice and butanol fraction for 14 days significantly increased the platelet count to 1073.50 ± 29.6 and 1189.80 ± 36.5 × 103 cells/μL, respectively. C.papaya extracts normalized the elevated bleeding and clotting time and decreased oxidative markers by increasing endogenous antioxidants. A marginal increase in the serum thrombopoietin (TPO) level was observed in Cyp treated group compared to normal and treatment groups. Low expression of CD110/cMpl receptor found in Cyp treated group was enhanced by C. papaya extracts (CPJ) and CPJ-BT. Furthermore, examination of the morphology of bone marrow megakaryocytes, histopathology of liver and kidneys revealed the ability of CPJ and fractions in mitigating Cyp-induced thrombocytopenia in rats. ConclusionC. papaya leaf juice enhances the platelet count in chemotherapy-induced thrombocytopenia by increasing the expression of CD110 receptor on the megakaryocytes. Hence, activating CD110 receptor might be a viable strategy to increase the platelet production in individuals suffering from thrombocytopenia.

The Effects of Extraction Conditions on Extraction Yield and Syringin Content in Producing Standardized Tinospora crispa Aqueous Extract with High Antioxidant Activity

The herbal plant known as Tinospora crispa is reported to have many beneficial effects on health and has great potential in future to be developed as a health product either in the form of traditional medicine, food supplements or in pharmaceutical preparations. However, so far knowledge on processing procedures to produce quality standardized extracts of this plant to be used in product development has still not widely reported. Therefore, the objective of this study was to determine the optimal extraction conditions for producing a standardized T. crispa aqueos extract (STCAE) with high extraction yield and high syringin content. Experiments were conducted to determine the effects of various extraction conditions involving temperature (25–100 ° C), extraction time (0.5–6 hours) and liquid (water) to solid ratio (5: 1–25: 1 ml of solvent per g stem dry). Using optimized conditions obtained, the extract was standardized based on syringin and was further investigated on its antioxidant activity through DPPH, FRAP and TBA bioassays. Results revealed that the optimum extraction conditions were found to be 1 h extraction time and 15:1 ml g−1 liquid-to-solid ratio. For the extraction temperature, 60°C was found to be the best. STCAE was produced on the basis of the extract to contain with at least 0.4 wt% of syringin. STCAE was found to possess high antioxidant activities through DPPH, FRAP and TBA bioassays.

Interface between orthodox and traditional medicine and alternative paradigm for integrating orthodox and traditional health care in Nigeria

Traditional medicine refers to the knowledge, skills and practices based on the theories, beliefs and experiences indigenous to different cultures, used in the maintenance of health and in the prevention, diagnosis, improvement of physical and mental illness. Herbal treatments are the most form of traditional medicine and 70 – 80% of the African region has used a form as primary health care. There is little doubt that the use of herbal medicines is growing and one of the most problems found in medicinal plants is the absence of clinical, toxicological and pharmacological studies. Many African countries depend on herbal medicines because of their efficacy, affordability and availability. The future of African traditional medicine is bright if view in the context of service provision, increase of health care coverage, economic potential and poverty reduction. Formal recognition and integration of traditional medicine into conventional medicine would be of good advantage.

Sedative effects of inhaled Perilla frutescens essential oils on mice

Perilla frutescens is an ingredient for cooking and for Japanese traditional medicine formulations. Essential oils extracted from P. frutescens are classified according to their composition, which are genetically regulated. Here, we extracted five types of essential oil from P. frutescens and studied their sedative activities. We grew P. frutescens strains that give oils of type PK, PA, PP, EK, and C, and extracted the essential oils by hydrodistillation. We then measured the spontaneous locomotor activity of mice who had inhaled the oils in an open field test. All types of essential oil except the PK type decreased the spontaneous locomotor activity of mice. The effective doses were 4.0 × 10-3 to 4.0 × 10-2mg/cage (PA type), 4.0 × 10-4mg/cage (PP type), 4.0 × 10-5mg/cage (EK type), and 4.0 × 10-5 to 4.0 × 10-3mg/cage (C type). Our results show that the essential oils of type PA, PP, EK, and C have a sedative effect.

Purification, Detoxification, and Incineration Methods of Minerals and Metals in Traditional Medicine Formulations of Sri Lanka.

Background Herbo-mineral therapies are very popular in traditional medical systems and formulations consisting of specific minerals or metals or mixture of both and mixed with organic components derived from plants. Purification/detoxification or incineration procedures play an important role to detoxify these and metals and minerals. Objective In the present review, an attempt was made to gather herbo-mineral formulations which are used commonly in traditional medicinal systems in Sri Lanka and recapitulate the purification/detoxification or incineration techniques. Method Commonly used herbo-mineral formulations are collected from a text book of Vatikaaprakarana. However, the purification/detoxification and incineration techniques for all minerals/metals are not mentioned in Vatikaaprakarana, and these techniques were collected from journal articles published between 1st January 2000 and 1st June 2020 through searching PubMed (US National Library of Medicine, USA), Science Direct (RELX Group, Netherlands), and Semantic Scholar (Allen Institute for Artificial Intelligence, USA). Results Ten herbo-mineral formulations were selected, and purification/detoxification or incineration techniques were described in brief for copper sulphate, aluminum sulfate, borex powder, sulphur, sodium chloride, cinnabar, arsenicals, realgar, orpiment, ammonium chloride, magnesium silicate, zinc, and mercury. Conclusion The review has demonstrated different types of purification/detoxification or incineration techniques of minerals used in herbo-mineral preparations. In addition, there is an urgent need for comprehensive survey or evaluation to check whether purification/detoxification or incineration techniques of metals/minerals are practiced properly in the country.