The development of modern public relations shows the formation of new subjects of constitutional law, since the content of mutual relations between them is increasingly moving into the digital space, where updated constitutional values arise. The current legal regulation is much more conservative and cannot respond to the rapidly developing relations in this area in a timely manner. Indirectly it can be confirmed by the fact that the programmatic regulation is gaining popularity when the state is trying to influence or at least predict the future through projects, plans, complexes of planned activities, etc. In this regard, theoretical approaches are proposed to optimize classical legal regulation. The main purpose of the paper is the application of the author’s theory of relations of subjects of constitutional law to assess public relations through establishing the presence of new subjects and conditions for their mutual influence. The expediency of this activity is due to the desire for subsequent proposals of a theoretical nature in order to develop a system of legal and regulatory framework. The list of tasks of the work is determined by those spheres of public relations that are selectively considered in the paper, namely high-tech medicine, the Internet space, the system of education and upbringing of youth, ensuring and protecting human rights in the electoral process, etc. Of course, this list is not exhaustive. The author analyzes phenomena regulated by law and that take place in foreign countries and the international practice of transnational corporations. This indicates the use of a comparative legal method. The key result of the conducted research is the proposal to revise the established rules for the analysis and systematization of public relations implemented in the digital space or otherwise related to it. Regulatory legal regulation should also be reoriented to this.