The corrugated plate dryer is an important steam-water separation equipment in the steam generator in the secondary loop of nuclear power plants. Therefore, it is very important to understand the process and mechanism of liquid film rupture on the wall surface of the corrugated plate dryer. In this paper, for the first time, the process of rupture of the liquid film on the surface of the corrugated plate is studied. The mechanism of liquid film rupture on the wall surface of vertical corrugated plate was studied experimentally. The high-speed camera was used to collect the image of the broken liquid film, and the experimental research on the broken position, the broken process and the broken shape of the liquid film was carried out. The results show that the rupture of the liquid film on the wall surface of the corrugated plate under the horizontal shear of air flow mostly occurs at the upper middle position of the main flow of the liquid film. And the rupture position moves up with the increase of the Reynolds number of the liquid film. Liquid film rupture needs to go through the process of stable flow, single strip-shaped liquid film detachment, two strip-shaped liquid film formation, and finally chaotic disordered rupture. The angle between the two strip-shaped liquid films is positively related to the Reynolds number of the liquid film.