In this study, optimized design schemes for improving the thermo-hydraulic performance of delta-winglet vortex generators (VGs) arranged in multiple rows in fully developed forced-convection channel are investigated numerically for a range of Re numbers from 5000 to 20,000. The height ratio (HR) of VGs with respect to the channel and the longitudinal pitch ratio (PR) of VG arrangement are considered as the main parameters for the design of multiple rows of VG, and a comprehensive investigation was carried out from the aspects of thermal performance, flow characteristics, entropy generation rate and energy saving. For better thermal performance, HR = 1/6 and PR = 16 are the most recommended design parameters (PEC = 1.33–1.38), and it is necessary to avoid design parameters with too small a PR or HR. From the local flow field analysis, the multiple rows arrangement of VG can promote the diffusion and enhancement of the secondary flow to realize the enhancement of thermal mixing along the flow direction. Finally, the entropy generation rate is analyzed to assess the irreversibility level for different design parameters, the optimized multiple row arrangement design of VG is given by the performance evaluation plot in terms of energy saving considerations.
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