In paper we offer a report on the results of the comparative analysis of existing concepts of the functioning and development of Smart Logistic. In paper shown that at present ITS is the most developed concept for the implementation of Smart Logistic and, in its essence, approaches the essence of the CPS concept as intelligent automatic (or close to automatic) control systems for physical objects and processes of various nature. Within the framework of the CPS concept, through test studies using various AI methods (GA, ESA, AA and ACAmod), it was determined that the most effective method for optimizing the route of freight traffic is ACAmod, which allows dynamic routing of logistics flows in real time, taking into account the non-stationary dynamics of TF. One of the promising areas for further research, the authors consider the creation of an intelligent system for supporting decisions on transport and logistics management of freight traffic in real time taking into account the influence of external factors of various nature on the transportation processes. The creation of such a system should be based on a modern interpretation of the concept of ITS as a CPS for Smart Logistics. In addition, in this report within the concept of the Cyber-Physical Systems are show the results of determining of the most effective method for optimizing of logistics flows in real time, taking into account the non-stationary dynamics of traffic flows
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