Marigold Flowers Research Articles

Statistical optimisation of enzymatic pre-treatment process of marigold flower waste for enhanced hydrolysis and complete release of lutein ester through Taguchi orthogonal design

ABSTRACT The lutein ester of the marigold flower is entrapped in the matrix of pectin, cellulose, hemicellulose and lignin which cannot be released by moderate acidic, alkaline treatment or enzymatic treatment with a single enzyme. Five different parameters are optimized in the current study for two response factors: lutein ester extraction (LEEP) and floral solid hydrolyzed percentage (FSHP). Three commercially available enzymes, namely pectinase, cellulase, and xylanase, at various temperatures and time intervals were utilised to optimise the enzymatic hydrolysis of flower biomass. An L27 orthogonal Taguchi experimental design was employed, investigating temperature (25–35 °C), time (10–30 days), and enzyme levels (pectinase, cellulase and xylanase at 0–1 mL). The optimal conditions for 100% lutein ester extraction from marigold flower waste were: temperature 35 °C, 20 days, and enzymes 1 mL/200 g each of pectinase (2600 µPG/g), cellulase (20000 CMC U/g), and xylanase (300000 U/g). Thus, it could be concluded that optimisation by the Taguchi method could be used to develop an enzyme cocktail for the hydrolysis of marigold flowers to obtain the best yield of lutein ester. The aim is to enhance the yield of lutein ester through the optimisation of the enzymatic pre-treatment of the marigold flower.

Isovalent Doping of Cu2+ Induced Elastic Strain on Cobalt Spinel Oxides for Enhancing Room Temperature Thermoelectric Application

A novel thermoelectric material, CuxCo1-xAl2O4 (x=0.02-0.10) was developed using a microwave combustion method with urea as the fuel source and investigated for the room temperature thermoelectric applications. The spinel phase was analyzed using XRD, and the spinel Co-O-Al bond were identified at the band region of 779cm-1 in the FT-IR spectrum. SEM revealed a marigold flower like pattern in the morphology, while TEM showed a cubic morphology, and elemental composition are confirmed by EDAX. Additionally, optical characteristics of the pristine and Cu doped samples were thoroughly analyzed by UV- DRS spectroscopy. EPR measurement confirmed the presence of free electrons which are crucial for electrical conductivity. XPS analysis further verified the oxidation states of each element. To investigate the thermoelectric properties of CoAl2O4 and CuxCo1-xAl2O4 (x=0.02-0.10), hall measurements were conducted, revealing the highest carrier concentration was found as 8.728×1016cm-3 for Pristine CoAl2O4. Notably, the highest electrical conductivity was found as 2.48×10-2 Scm-1, while the lowest thermal conductivity measured was 0.0522W/mK for Cu0.10Co0.90Al2O4. The Seebeck co-efficient for the pristine sample was 730 μV/K, which decreased to 427 μV/K for Cu0.10Co0.90Al2O4. The highest power factor observed was 5.1 nWcm-1K-2 for Cu0.10Co0.90Al2O4. This study presents the obtained results and the fabrication of a wearable device using p-type (CoAl2O4) and n-type (Cu0.10Co0.90Al2O4) materials, achieving an output of 3.6mV with a temperature difference of 1.5K”.

Plants-extracts mediated CuS nanoparticles: An effective antibacterial agent

Antibacterial activity of plant-mediated synthesized CuS nanoparticles against gram-positive Bacillus subtilis and gram negative Pseudomonas putida is studied in this presented work. A facile hydrothermal approach was followed to synthesize spherical shaped CuS nanoparticles using flowers extract of Tagetes patula (S1), leaves extract of Azadirachta indica (S2), and bark extract of Terminalia arjuna (S3). Crystal phase identification, average crystallites size, surface morphology, absorbance spectra and energy band gap analyses of samples were further determined using XRD, SEM, and UV-DRS spectroscopy respectively. Furthermore, under irradiation of visible light, antibacterial activity of marigold flowers mediated (S1), neem leaves mediated (S2), and arjuna bark mediated (S3) CuS samples were studied. XRD data confirmed the marigold mediated CuS sample has relatively smaller crystallites size of 10.67 nm. The estimated band gap energies for respective S1, S2, and S3 samples are 174 eV, 175 eV, and 177 eV. The antibacterial analysis of S1 sample displays its excellent antibacterial activity with the formation of relatively large inhibition zones of 29 mm and 30 mm diameters, against Bacillus subtilis and Pseudomonas putida respectively. The demonstrated antibacterial activity of biocompatible CuS nanoparticles suggests their potential use in biomedical applications.

UPLC-MS/MS-based metabolomics combined to chemometrics reveal the anti-inflammatory metabolites of African Marigold (Tagetes erecta L.) flowers

African Marigold (Tagetes erecta L.) is widely recognized for its ornamental value and therapeutic properties, particularly its anti-inflammatory potential. This study employs UPLC-MS/MS-based metabolomics combined with chemometric analysis to identify bioactive metabolites contributing to the anti-inflammatory effects of T. erecta flowers. The flowers were fractionated using hexane, methylene chloride, ethyl acetate, and butanol, and a total of 79 metabolites were identified across the fractions, including flavonoids, phenolic acids, tannins, quinic acids, terpenoids, alkaloids, and amino acids. The anti-inflammatory efficacy of each fraction was assessed in vitro by evaluating their impact on the expression of four pro-inflammatory cytokines (TNF-α, IL-6, IL-1β, and IFN-γ) in LPS-stimulated leukocytes using PCR. Orthogonal Projections to Latent Structures was employed to determine the key metabolites contributing to the observed bioactivity. The analysis revealed that the methylene chloride and ethyl acetate fractions exhibited the most potent anti-inflammatory effects, primarily due to the presence of flavonoids and phenolic acids. Notably, disyringic acid hexoside, ellagic acid, gallic acid, p-coumaric acid, and quercetagetin dimethyl ether were identified as major anti-inflammatory agents based on their high correlation coefficients with cytokine inhibition and their substantial concentrations within the active fractions. These findings underscore the importance of selecting appropriate extraction solvents to isolate specific bioactive compounds and provide a deeper understanding of the metabolite profiles that contribute to the anti-inflammatory properties of T. erecta flowers.

Study on the Marketing of Marigold Flower in Varanasi District of Uttar Pradesh, India

Study on the Marketing of Marigold Flower in Varanasi District of Uttar Pradesh, India

Effectiveness of treated sludge as plant growth modulator on the phytometabolics of African marigold (Tagetes erecta)

The current study investigated the effects of treated sludge on the phytochemical composition of African Marigold (Tagetes erecta) flowers. African Marigold flowers were cultivated with treated sludge and their phytochemical profiles were analyzed using gas chromatography-mass spectrometry (GC-MS). Flowers from plants treated with sludge increased in various bioactive compounds, including ?-Pinene, linalool, ?-Caryophyllene, quercetin and luteolin, recognized for their antioxidant, anti-inflammatory and antimicrobial properties. The study underscores the potential of treated sewage sludge as a sustainable soil amendment to improve plant growth and Marigold flowers' phytochemical profile. This study provides valuable prescience into agricultural practices that ensure sustainability and highlights the potential of sewage sludge as a beneficial resource for enhancing crop quality and bioactive compound content.

Chemical modification of marigold (Tagetes erecta) dye via diazo-coupling reaction for enhanced dyeing on polyester: A sustainable approach

Plant-derived natural extracts contain large amounts of polyphenolic compounds, presenting opportunities for chemical modification. The present study deals with the extraction of dye from Marigold (Tagetes erecta), a widely cultivated and commercially utilised flower, using water as an extraction medium followed by its chemical modification for sustainable synthesis of yellow dye and dyeing of polyester fabric. Phytochemical analysis and FTIR spectroscopy of the natural dye extract from Marigold flowers indicated the presence of polyphenolic flavonoids. The water-extracted natural dye was subsequently chemically modified with aniline, a primary aryl amine, via diazotisation and coupling reactions to yield a semi-synthetic natural dye with a 1.2 ± 0.3 g yield. The major constituents in the marigold natural extract and the Modified Marigold Extract (MME) dye were characterised using High-Resolution Liquid Chromatography-Mass Spectrometry (LC-HRMS). The marigold water extract contained a high concentration of Gossypetin 8-Glucoside, a yellow-coloured flavonoid compound with a mass-to-charge ratio (m/z) of 480.0904. LC-HRMS analysis further confirmed the presence of a constituent (m/z 424.0485) in the MME dye, corresponding to the predicted mass of chemically modified Gossypetin 8-Glucoside. The MME dye was subsequently employed for dyeing polyester fabric, exhibiting maximum colour strength at 10 % shade under acidic condition. The dyeing performances of the MME-dyed fabrics were evaluated in terms of fastness and post-dyeing strength. This study demonstrates a unique and novel approach to develop a yellow semi-synthetic natural dye, emphasising its potential utility for polyester dyeing.

Characterization of Marigold Flower (Tagetes erecta) Extracts and Microcapsules: Ultrasound-Assisted Extraction and Subsequent Microencapsulation by Spray Drying.

Ultrasound-assisted extraction using response surface methodology was employed to extract marigold flower, resulting in a marigold flower extract (MFE) with elevated levels of total phenolic compounds (TPCs), total flavonoid content (TFC), total carotenoid content (TCC), and antioxidant activity, as assessed by 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) assays, under conditions of 40 °C temperature, 15 min extraction time, and 68% ethanol concentration. The MFE was subsequently encapsulated using spray drying with 45% maltodextrin (MD) (MFE-MD; 1:1, 1:2) and 20% gum arabic (GA) (MFE-GA; 1:2, 1:3). The MD (1:2 ratio) sample showed the highest encapsulation yield, while the 45% MD (1:1 ratio) sample exhibited the highest encapsulation efficiency (p ≤ 0.05). Samples containing 45% MD (1:1 ratio) and 20% GA (1:2 ratio) had the highest moisture content, with the 45% MD (1:1 ratio) sample showing the lowest water activity (p > 0.05). These samples also displayed higher L* and a* values compared to the 20% GA samples, which had increased b* values (p ≤ 0.05). Micrographs of the 20% GA (1:3 ratio) and 45% MD (1:2 ratio) samples revealed spherical shapes with smooth surfaces. The 20% GA (1:2 ratio) microcapsules exhibited the highest total phenolic content (TPC) among the samples (p ≤ 0.05). Thus, ultrasound-enhanced extraction combined with response surface methodology proved effective in producing functional food ingredients from plants.

Termite mound soil based potting media: a better approach towards sustainable agriculture.

Termite mound soils are known to possess unique physico-chemical and biochemical properties, making them highly fertile. Considering their rich nutrient content, the objective of the current experiment is to assess the physico-chemical properties and enzyme activities of termite mound based potting media and evaluate theirperformance for further exploration in floriculture. Potting media consisting of termite mound soil (TS) of a subterranean termite, Odontotermes obesus were prepared in 7 different combinations with garden soil (GS), sand (S) and farmyard manure (FYM) and a control (without termite mound soil), i.e., T1 (TS, GS, S, FYM (v:v:v:v /1:2:1:1)), T2 (TS, GS, S, FYM (v:v:v:v / 2:1:1:1)), T3 (TS, S, FYM (v:v:v / 2:1:1)), T4 (TS, GS, FYM (v:v:v / 2:1:1)), T5 (TS, GS, S (v:v:v / 2:1:1)), T6 (TS, S, FYM (v:v:v / 3:1:1)), T7 (TS, S, FYM (v:v:v / 1:1:2)) and control (GS, S, FYM (v:v:v / 2:1:1)). The samples were then analysed in laboratory. Experimental analysis on physico-chemical and biological parameters revealed superiority of T7 (TS, S, FYM (v:v:v / 1:1:2)) in terms of pH (7.15), organic carbon (2.13%), available nitrogen (526.02 kg ha-1), available phosphorus (56.60 kg ha-1), available potassium (708.19 kg ha-1), dehydrogenase activity (18.21 μg TTF g-1 soil day-1), Phosphomonoesterase (PME) activity (46.68 54 μg p-nitrophenol/gsoil/h) and urease activity (3.39 μg NH4-N g-1 soil h-1). Whereas T4 (TS, GS, FYM (v:v:v /2:1:1)) registered superiority in terms of PME activity (50.54 μg p-nitrophenol/gsoil/h), Fluorescein diacetate (FDA) activity (11.01 μgfluorescein/gsoil/h) and Soil Microbial Biomass Carbon (SMBC) (262.25 μg/g). Subsequent to the laboratory analysis, two best potting mixtures (T7 & T4) were selected and their performance was assessed by growing a test crop, Tagetes erecta cv. Inca Orange. Considering the growth parameters, the potting media: T7 was found to be significantly superior in terms of plant spread (39.64 cm), leaf area index (4.07), fresh weight (37.72 g), yield (317.81 g/plant), and diameter (9.38 cm) of flower over T4 & control. The Benefit:Cost (B:C) ratio meaning the ratio of net returns to total cost of cultivation was determined. The B:C ratio of raising marigold flower as potted plant in T7 was 1.10 whereas the B:C ratio of the potting mixture of T7 was 2.52. This shows that T7 potting media is also economically viable choice for commercial purposes.

Phytochemical Test and Antioxidant Activity of Aqueous Extract of Marigold Flower

Natural medicines are increasingly in demand for safety reasons and are believed to be able to cure certain diseases. Literacy reveals that the marigold flower (Tagetes erecta L.) has medicinal potential as an antioxidant, anti-bacterial, anti-inflammatory, and anti-carcinogen. This research aimed to identify marigold flower aqueous extract's phytochemical content and antioxidant activity. The method used in this exploratory research was the maceration of marigold flower simplicia using distilled water for 24 hours, followed by evaporation to obtain marigold flower aqueous extract. Then, phytochemical screening and antioxidant bioactivity tests were carried out using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. The results of phytochemical screening showed that marigold flower water extract contained flavonoids, phenols, alkaloids, and tannins. Meanwhile, the antioxidant activity test obtained an IC50 value of 50.77 ppm. From these results, it can be concluded that the aqueous extract of marigold flowers has medicinal potential with vigorous antioxidant activity.

Sustainable scouring of cotton using extracts from wood ash and soapnut and its optimisation by response surface methodology

AbstractThe non‐cellulosic impurities like oil, wax, and pectins present in the cotton fibre adversely impact wetting. Consequently, these impurities must be removed during the pretreatment process to prevent unevenness of subsequent coloration. Generally, an alkaline treatment with petroleum‐based synthetic surfactants is done, which is called scouring. This study attempts to develop an environmentally safe alternative using alkali from wood ash extract (WAE) and surfactant from soapnut extract (SE). The factors of WAE (10%–30%), SE (5–15 g/L), temperature (75–95°C), and time (20–60 min) were optimised using response surface methodology. A concentration of 20% WAE and 10 g/L SE at 90°C for 30 min was found to be adequate to remove impurities. The statistically optimised method showed good hydrophilicity, indicated by an average wetting time of 15 s, and 2.7% weight loss. The scoured fabric was subsequently dyed with natural dye extracted from marigold flowers and reactive dye. The scoured cotton was evaluated by weight loss, wettability, tensile strength, whiteness index, and colour value (K/S) and showed comparable results to conventional scouring.

Factors Influencing the Growth of Marigold Flowers in (M.P.)

Factors Influencing the Growth of Marigold Flowers in (M.P.)

Study of Photogalvanic Effect by using Marigold Flower as Natural Photosensitizer, Xylose as Reductant and Tween 80 as Surfactant for Solar Radiation Conversion and Storage

Objective: A study work plan has been put up for methodical work in the field of solar energy Photogalvanic (PG) cells. It was suggested and required to do experiments with PG cells in sunlight conditions. Improving the conversion of solar energy into electricity and storing it in PG cells is the goal of our study. Method: An H-shaped glass tube with two arms was manufactured using the specially developed PG (Figure 1) cell. Many characteristics of a PG cell with an MG+D-Xylose+Tween-80 system was investigated. Findings: The open circuit voltage, voltage at dark, photopotential (PP), and photocurrent (PC) recorded in this investigation are 1080.00 mV, 165.00 mV, 915.00 mV, and 674.00 µA, respectively. The Fill Factor (FF) and Conversion Efficiency (CE) that were observed 1.891% and 0.2732, respectively. Novelty: Through the adjustment of PG cells' numerous parameters, the effects of solar energy were investigated. Based on the aforementioned results, PG systems have demonstrated through experimentation that they are an effective system and should be further investigated, particularly with regard to improving solar energy output and storage. Keywords: D-Xylose, Tween - 80, Marigold, Photocurrent, Natural dye

Isolation of flavonoids from Tagetes patula(French Marigold) flowers: Cytotoxic and oxidant activity in human cervical carcinoma cells

Tagetes patula, known as French Marigold, belongs to the family Asteraceae. Human papillomavirus infection is considered one of the causes of cervical cancer. This study assessedthe cytotoxic activity and intracellular oxidative capacity of compounds isolated from extract of T. patulaflowers as anti-cancer cervical agents. Fraction F6 of n-butanol extract was subjected to column chromatography and HPLC-ESI-MS. The isolated compounds of T. patulawere used to examine cytotoxic activity and the production of total reactive oxygen species in SiHa and HeLa cells; the cells were also characterized using scanning electron microscopy. Patulitrin was cytotoxic to SiHa and HeLa cells. An increase in ROS production was observed at different times of treatment of cells with patuletin and patulitrin. Scanning electron microscopy showed morphological changes in SiHa and HeLa cells. Thus, compounds isolated from T. patulahave great treatment potential against cervical cancer.

Efektivitas Biolarvasida Kombinasi Ekstrak Daun Sirsak (Annona muricata) dan Bunga Marigold (Tagetes erecta L.) sebagai Pembasmi Jentik Nyamuk

This research aims to determine the effectiveness of using a biolarvicide combination of soursop leaf extract and marigold flowers as an exterminator for mosquito larvae. This research included a laboratory experiment using a completely randomized 2 factorial design. The first factor is a combination of soursop leaf extract and marigold flowers, namely, a) 75%:25% (F1); b) 50%:50% (F2); c) 25%:75% (F3). The second factor is the treatment dose, namely, a) 1% (D1); b) 2% (D2); c) 2.5% (D3). Each factor was repeated 3 times. Data analysis uses a non-parametric test, namely Kruskal-Wallist. The results of the study showed that the soursop leaf and marigold flower extract formula 75%:25% was most effective against mosquito larvae mortality at a dose of 2.5% within an observation period of 6 hours. In conclusion, soursop leaf and marigold flower extracts are effective mosquito larva repellents. Keywords: Biolarvicide, Marigold Flowers, Soursop Leaves, Effectiveness, Mosquito Larvae

Bioavailability of Lutein from Marigold Flowers (Free vs. Ester Forms): A Randomised Cross-Over Study to Assess Serum Response and Visual Contrast Threshold in Adults.

Lutein (Lut) and zeaxanthin (Zeax) are found in the blood and are deposited in the retina (macular pigment). Both are found in the diet in free form and esterified with fatty acids. A high intake and/or status is associated with a lower risk of chronic diseases, especially eye diseases. There is a large global demand for Lut in the dietary supplement market, with marigold flowers being the main source, mainly as lutein esters. As the bioavailability of Lut from free or ester forms is controversial, our aim was to assess the bioavailability of Lut (free vs. ester) and visual contrast threshold (CT). Twenty-four healthy subjects (twelve women, twelve men), aged 20-35 and 50-65 years, were enrolled in a cross-sectional study to consume 6 mg lutein/day from marigold extract (free vs. ester) for two months. Blood samples were taken at baseline and after 15, 40, and 60 days in each period. Serum Lut and Zeax were analysed using HPLC, and dietary intake was determined with a 7-day food record at the beginning of each period. CT, with and without glare, was at 0 and 60 days at three levels of visual angle. Lut + Zeax intake at baseline was 1.9 mg/day, and serum lutein was 0.36 µmol/L. Serum lutein increased 2.4-fold on day 15 (up to 0.81 and 0.90 µmol/L with free and ester lutein, respectively) and was maintained until the end of the study. Serum Zeax increased 1.7-fold. There were no differences in serum Lut responses to free or ester lutein at any time point. CT responses to lutein supplementation (free vs. ester) were not different at any time point. CT correlated with Lut under glare conditions, and better correlations were obtained at low frequencies in the whole group due to the older group. The highest correlations occurred between CT at high frequency and with glare with serum Lut and Lut + Zeax. Only in the older group were inverse correlations found at baseline at a high frequency with L + Z and with Lut/cholesterol and at a low frequency with Lut/cholesterol. In conclusion, daily supplementation with Lut for 15 days significantly increases serum Lut in normolipemic adults to levels associated with a reduced risk of age-related eye disease regardless of the chemical form of lutein supplied. Longer supplementation, up to two months, does not significantly alter the concentration achieved but may contribute to an increase in macular pigment (a long-term marker of lutein status) and thus improve the effect on visual outcomes.

The influence of the main elemental constituents of thousand year old barai mud extension of shades of natural dyed silk from marigold flowers

This research aimed (1) to study the main element of thousand year old mud and types of color-giving substances from marigold flowers and (2) to study the causes of silk color change from dark yellow to dark green at Bankhokmuang, Chorakhemark Sub-district, Prakhonchai District, Buriram Province. Firstly, the researcher studied the element of the mud from Barai Prasat Muang Tam and Barai Kuti Ruesi, using EDXRF. Secondly, the researcher studied types of phytochemicals in marigold extract using HCl solution and NaOH solution. Finally, the researcher dyed the silk with marigold flower extract mixed with alum and dyed it with iron ion solution and the mud solution from both sources. The results showed that both muds had the highest amount of Fe2O3, 64.03% of Barai Prasat Muang Tam mud and 44.22% of Barai Kuti Ruesi mud. The coloring substance of marigold extract was flavonoids and had good water solubility. Then the researcher dyed the silk with marigold flower extract mixed with alum because alum contained Al3+ions. The silk was dark yellow. The silk was divided into three groups to be dyed again. The first group was dyed with 1,000 ppm iron ion solution. The second group was dyed with a solution of Barai Prasat Muang Tam mud. The third group was dyed with a solution of Barai Kuti Ruesi mud. All group color changed from dark yellow to dark green. Thus, iron ion solution and both of Barai mud solution were rich in iron ion. This complex compound could form with flavonoids which made golden yellow color turns dark green and sticks to silk threads. It was also water insolubility. The color was not faded. All groups had different shade values at the significance level of 0.05. GRAPHICAL ABSTRACT HIGHLIGHTS Study the main element of thousand year old mud Study area at at Bankhokmuang, Chorakhemark Sub-district, Prakhonchai District, Buriram Province. Causes the color of the silk thread to change from yellow to dark green

Characterization and Discrimination of Marigold Oleoresin from Different Origins Based on UPLC-QTOF-MS Combined Molecular Networking and Multivariate Statistical Analysis.

Marigold oleoresin is an oil-soluble natural colorant mainly extracted from marigold flowers. Xinjiang of China, India, and Zambia of Africa are the three main production areas of marigold flowers. Therefore, this study utilized ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS/MS) technology, combined with Global Natural Products Social Molecular Networking (GNPS) and multivariate statistical analysis, for the qualitative and discriminant analysis of marigold oleoresin obtained from three different regions. Firstly, 83 compounds were identified in these marigold oleoresin samples. Furthermore, the results of a principal component analysis (PCA) and orthogonal partial least squares discriminant analysis (OPLS-DA) indicated significant differences in the chemical compositions of the marigold oleoresin samples from different regions. Finally, 12, 23, and 38 differential metabolites were, respectively, identified by comparing the marigold oleoresin from Africa with Xinjiang, Africa with India, and Xinjiang with India. In summary, these results can be used to distinguish marigold oleoresin samples from different regions, laying a solid foundation for further quality control and providing a theoretical basis for assessing its safety and nutritional aspects.

Technological insights into lutein isolation from marigold flower and their diverse applications: a compendious review

Technological insights into lutein isolation from marigold flower and their diverse applications: a compendious review

Electrospun Nanofibers Loaded with Marigold Extract Based on PVP/HPβCD and PCL/PVP Scaffolds for Wound Healing Applications.

Marigold flower is a traditionally used plant material topically applied on the skin due to its anti-inflammatory properties and antibacterial activity. This potential of action justifies the implementation of marigold extract in nanofiber scaffolds based on poly-vinylpyrrolidone/hydroxypropyl-β-cyclodextrin (PVP/HPβCD) and polycaprolactone/polyvinylpyrrolidone (PCL/PVP) obtained by electrospinning for wound treatment. Using SEM, the morphology of electrospun scaffolds showed a fiber diameter in the range of 298-527 nm, with a uniform and bead-free appearance. ATR-FTIR spectroscopy confirmed the presence of marigold extracts in nanofibrous scaffolds. The composition of the nanofibers can control the release; in the case of PVP/HPβCD, immediate release of 80% of chlorogenic acid (an analytical and functional marker for marigold extract) was achieved within 30 min, while in the case of PCL/PVP, the controlled release was achieved within 24 h (70% of chlorogenic acid). All systems showed weak antibacterial activity against skin and wound-infecting bacteria Staphylococcus aureus (MIC 100 mg/mL), and Pseudomonas aeruginosa (MIC 200 mg/mL) and yeasts Candida albicans (MIC 100 mg/mL). Analysis of the effect of different scaffold compositions of the obtained electrofibers showed that those based on PCL/PVP had better wound healing potential. The scratch was closed after 36 h, compared to the 48 h required for PVP/HPβCD. Overall, the study shows that scaffolds of PCL/PVP nanofibers loaded with classic marigold extract have the best potential as wound dressing materials because of their ability to selectively modulate inflammation (via inhibition of hyaluronidase enzyme) and supportive antimicrobial properties, thereby aiding in the early stages of wound healing and repair.