In this work we present numerical results of pool boiling flow in a turbulent Rayleigh-Bénard convection configuration, using our in-house code in a cubical geometry. The problem in hand is encountered in various natural phenomena as well as in industrial applications. An Eulerian-Lagrangian approach is developed for the mixture of liquid water and vapor bubbles. The liquid mean temperature is close to the saturation temperature and is governed by the quasi-incompressible Navier-Stokes equations that are solved using DNS standards. The motion and growth/shrinkage of each individual vapor bubble is modeled and the backward effect of the bubbles on the fluid is accounted via momentum and energy exchanges between the two phases (two-way coupling), as well as variations in fluid phases volumetric fractions (volumetric coupling). In such pool configuration the non-dimensional parameters governing the flow are both those relative to Rayleigh-Bénard convection, namely Rayleigh number, Prandtl number and aspect ratio, and those to boiling, namely the overall vapor volumetric fraction, the bubble size based Reynolds number, the degree of superheat of the liquid scaled by the overall temperature difference, and the Jakob number (sensible heat to latent heat ratio).At first, we describe the model used and its corresponding validation, involving natural convection, isolated bubble dynamics and coupling between bubbly and bulk flows. In the second part, we consider the study of the relationship between heat transfer through the pool (Nusselt number) and the flow topology for different settings of the bubbly configurations.