To promote flood resilience and reduce the damaging effects of flood in urban areas, the paper proposes an urban flood adaptation model based on an urban hydrological model, combined with the capacity of the flood ecological infracstruture. This model includes allowing flood to enter the city and restoring the interaction between flood and riparian ecosystems. This approach is called flood adaptive ecological awareness. To implement this idea, the paper translates into urban landscape planning principles that consider flood as a resource for urban ecosystems, establishing flood storage spaces based on ecological infrastructure adapted to dynamics of flood. The ability to regulate, collect, penetrate and purify pollution with water is due to the participation of landscape ecological infrastructure and enhance the regulatory capacity to mitigate the harmful effects of flood on Can Tho urban areas in Mekong Delta region, Vietnam.