We report on the nonlinear transmission limits of various super-channel configurations in a flex-grid network upgrade scenario. In particular, we consider flexible data-rates ranging from 180Gb/s to 1.2Tb/s, employing either single-carrier, dual-carrier, or penta-carrier polarization multiplexed m-state quadrature amplitude modulation (PM-8QAM/PM-16QAM) -termed as super-channels, and establish transmission performance margins for each configuration, both with and without super-channel fiber nonlinearity compensation. Our results show that the benefit of intra super-channel nonlinearity mitigation (nonlinear compensation addressing full super-channel bandwidth) reduces with increasing sub-carrier count within the super-channel, and that single-carrier super-channel achieves the maximum improvement from nonlinearity mitigation (up to ~4.5dB, in Q-factor), better than dual-carrier (up to ~3.5dB) and penta-carrier (up to ~2dB) configurations. Moreover, the maximum reach improvement, compared to linear compensation only, is found to be ~170% (180Gb/s, PM-8QAM), ~150% (240Gb/s, PM-16QAM), ~100% (360Gb/s, PM-8QAM), ~100% (480Gb/s, PM-16QAM), and ~65% (1.2Tb/s, PM-16QAM).