Finite element fingertip models are useful tools to assess product ergonomics. While “real geometry” approaches provide accurate results, developing models requires medical images. “Simpified geometry” approaches have to date not been tested to see whether they can provide equally accurate results in terms of mechanical response, i.e. force-displacement response and dimensions of fingertip contact area. Four fingertip models were built either from medical images (Visible Human project) or from simplified geometries. Simulations of fingertip flat contact compression at 20[Formula: see text] were performed. A 2nd order hyperelastic material property was used to effectively reproduce the mechanical behavior of the fingertip. Models based on simplified geometries such as conics proved as accurate as models reconstructed from medical images. However, accurate positioning of the bony phalanx is paramount if a biofidelic mechanical response is to be reproduced.