Bolted flange joint disk-drum structures (BFJDDSs) are key components in aero-engines, however, bolt looseness inevitably occurs due to extreme service conditions. This can cause the bolted joint interface to exhibit complex contact behaviors, which significantly complicate the vibration characteristics of BFJDDSs. Existing dynamic models for BFJDDSs have not considered the effect of bolt looseness (slip and separation), so their vibration behaviors are not well understood. In this study, a unified nonlinear dynamic model for BFJDDSs considering different interface states (stick, slip, and separation) is proposed, which is effective under both bolt looseness and non-looseness (stick) conditions. The bi-linear hysteretic model combined with the piecewise linear model is used to simultaneously consider different interface states. The Kirchhoff plate theory, the Sanders’ shell theory, and the Euler-Bernoulli beam theory are used to derive the energy functions of the disk, drum, and flange, respectively. Then, the Lagrange equations are employed to derive the governing equations of BFJDDSs. Modal and nonlinear forced vibration experiments are carried out on a BFJDDS to prove the correctness of the proposed mathematical model. Research results show that the proposed mathematical model is able to achieve good predictions of nonlinear dynamic properties of BFJDDSs under both bolt looseness and non-looseness conditions. This model is also able to well predict the jumping phenomenon observed in the experiment.