In order to improve the fire retardancy of epoxy resin (EP), lamellar cobalt potassium pyrophosphate (LCPP) nanocrystal whiskers with a length of 100-300 nm were designed and synthesized by a liquid technique. LCPP with high thermal stability was blended into EP to prepare the EP/LCPP composites. The results show that the EP/LCPP composites have higher thermal stability and produce more residues compared to pure EP. The combustion results display that the LOI value of the EP/10wt%LCPP composites was significantly improved to 35.9%, and the EP/6wt%LCPP composite can reach a UL-94 V-1 rating. Additionally, the peak heat release rate and peak smoke production rate of the EP/10wt%LCPP composites dramatically decreased by 43.8% and 48.5%, respectively. The improved flame retardancy and smoke suppression are mainly attributed to the inherent physical barrier of LCPP and the excellent catalytic carbonization ability of LCPP.