This paper presents a fault tolerant scheme employing adaptive non-singular fixed-time terminal sliding mode control (AFxNTSM) for the application of robotic manipulators under uncertainties, external disturbances, and actuator faults. To begin, non-singular fixed-time terminal sliding mode control (FxNTSM) is put forth. This control method uses non-singular terminal sliding mode control to quickly reach fixed-time convergence, accomplish satisfactory performance in tracking, and produce non-singular and non-chatter control inputs. Then, without knowing the upper bounds beforehand, AFxNTSM is used as a reliable fault tolerant control (FTC) to estimate actuator faults and unknown dynamics. The fixed-time stability of the closed-loop system is established by the theory of Lyapunov analysis. The computer simulation results of the position tracking, control inputs, and adaptive parameters are presented to verify and illustrate the performance of the proposed strategy.