In this paper, a fixed-time convergence-integrated guidance and control (IGC) method is proposed, which considers terminal line-of-sight (LOS) angle constraint, full-state constraints, and input saturation. Firstly, an IGC design model considering the full coupling of three channels is constructed, and a fixed-time convergence disturbance observer is used to estimate and compensate the unknown disturbances in the model. Secondly, based on the fixed-time stability theory, sliding mode control, and backstepping control, a novel IGC scheme is carried out, and the second-order instruction filter is used to restrict the system states and control instructions. Furthermore, the fixed-time stability of the close-loop system is proved and the expression of convergence time upper bound is given. Finally, comparison simulation and Monte Carlo simulation verify the effectiveness and superiority of the proposed IGC algorithm.