Are firms that are managed and owned by females-only appraised differently than those where genders mix at the top? To answer this question, we study 7,467 small and medium-sized firms from 22 countries. We find that—when borrowing from banks—firms that are both managed and owned by females more often report binding credit constraints and higher interest rate payments than male-only firms: differences that we can attribute to taste-based discrimination. In contrast, if the manager and the owner have a different gender, we find no such differences with male-only firms. Hence, interestingly banks seem to assume that women invariably play second fiddle in the mixed-gender firms. We also show that discrimination between female-only and other firms disappears from economically more developed regions and from credit markets that are more competitive or dominated by transactional lenders.