The frequency of frailty is increasing with the aging world population. Frailty is a long-term process and physiopathological theory describes six different dysfunction systems to be considered (i.e. hemoglobin, IL-6, IGF-1, DHEA-S, HgbA1c, triceps skinfold, fine motor movement, micronutrients). The definition of frailty is an important task. Two different models have been described: the phenotype of frailty and cumulative deficit model. Symptoms and findings of frailty are commonly non-specific. Additionally extreme fatique, unexplained weight loss and infections are observed. Frailty is a leading cause of mortality and the prevalence is 4-59% depending on the definition. It is frequent in women and the prevalence increases with age (65–69: %4;>84:%26). Although the number of studies has increased in family medicine, further studies are needed. This field needs to be prioritized in family practice.