Accurate prediction of renewable energy generation acts as a critical role which not only provides short-term power generation in the future, but also facilitates scheduling and pre-configuration of energy storage systems. More importantly, the power generation prediction is of great significance to the demand response management (DRM) of renewable energy to participate in the electricity spot market. Therefore, DRM helps improve the stability and reliability of renewable energy systems. This paper presents a novel prediction-smoothing based methodology to reduce and eliminate the influence caused by the uncertainty of renewable energy output. Firstly, the Whale Optimization Algorithm (WOA) is combined with Long Short-Term Memory (LSTM) to predict short-term wind power output. Then, the Hampel-Butterworth-SG filtering strategy with outlier regression and specific risk band elimination is introduced. After that, according to the short-term output forecast results, the scheduling and pre-configuration scheme of peak-filling type energy storage is developed. Finally, based on the predicted renewable energy output and electricity price, the dynamic changes of demand response (DR) are calculated based on Logistics function, optimistic response and pessimistic response factors. Through extensive case studies, it is demonstrated that the assessment deviations in different scenarios is less than 5%, which are 0.64% for Scenario 1 and 3.64% for Scenario 2, and no additional penalty is required at this time. In addition, the proposed Demand Response Load Adjustment Rate (DRLAR) help compare the differences between predicted and actual DR, which are DRLAR = 0.03% in Scenario 1 and DRLAR = 0.01% in Scenario 2. Users are able to adjust the DR dynamically according to the electricity price to realize the optimal scheduling of their renewable resources. The proposed methodology creates a special connection between DRM and renewable energy prediction, which provides a reliable reference for future work.