During the collection process, the prostate capsule is prone to introduce salt and pepper noise due to gastrointestinal peristalsis, which will affect the precision of subsequent object detection. A cascade optimization scheme for image denoising based on image fusion was proposed to improve the peak signal-to-noise ratio(PSNR) and contour protection performance of heterogeneous medical images after image denoising. Anisotropic diffusion fusion (ADF) was used to decompose the images denoised by adaptive median filter, non-local adaptive median filter and artificial neural network to generate the base layer and detail layer, which were fused by weighted average and Karhunen-Loeve Transform respectively. Finally, the image was reconstructed by linear superposition. Compared with the traditional denoising method, the image denoised by this method has a higher PSNR while maintaining the image edge contour. Using the denoised dataset for object detection, the detection precision of the obtained model is higher.
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