Research objective. To analyze the epidemiological features of chronic hepatitis in the Russian Federation and in the Samara region.Materials and methods. The data of official statistics were analyzed: the materials of the Federal Service for Supervision in the Field of Consumer Protection and Human Welfare, the Office of the Federal Service for Supervision in the Field of Consumer Protection and Human Welfare in the Samara Region.Results. The long-term dynamics of the incidence of newly diagnosed chronic hepatitis B in the Russian Federation and the Samara region in 1999–2021 was synchronous. In 1999–2001 the incidence of HCV (Chronic hepatitis B) in the Russian Federation and the Samara region had maximum values of 16,00⁄0000–22,50⁄0000. In the Samara region, it was higher than in the country. As a result of systematic measures to vaccinate the population against HCV during the period of mass immunization (2006–2021), the rate of decrease in the incidence of HCV in the Samara region decreased from 14,5 0⁄0000 to 2,40⁄0000 and in the country – from 14,0 0⁄0000 to 4,50⁄0000. The introduction of immunization of the child population against HCV in the Samara region had a positive effect on the incidence of HCV. From 2000 to 2021, the incidence of HCV decreased by 9,4 times. If in 2000 the incidence of children with HCV was 4,20⁄0000 in the Russian Federation, in 2002–7,30⁄0000 in the Samara region, then in 2021 in the Russian Federation it decreased to 0,080⁄0000, no cases were registered in the Samara region.
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