The article is devoted to the problem of formation peculiarities of safety culture of future health and safety professionals under modern conditions. The security situation, which is under the influence of many complex dynamic processes, has been exacerbated by the anthropogenic pressure on the environment due to the pandemic, which is accompanied by the emergence of new risks and threats to humans. Therefore, the issue of people’s life and health safety is considered a priority in the context of ensuring sustainable development of the state and society as a whole. Ukraine has created a legal framework based on the Constitution of Ukraine and includes laws of Ukraine in the field of health, labor and environmental protection. In particular, based on the work of international and Ukrainian scientists in the field of security in Ukraine, the concept of education in the field of safety of human’s life and activity is implemented, within which it is taught a set of disciplines on labor protection. However, the current state of affairs suggests that future specialists formation of cultural safety peculiarities in the field of labor protection, especially under pandemic conditions, is insufficient and inconsistent. As security has become a priority goal and need of man, team and society as a whole, it is clear that the assimilation of this culture can be achieved through formation of the new system of views, values, norms and traditions of safe behavior. The purpose of the article is to substantiate the peculiarities of the culture of safety in a pandemic for future labor protection specialists during professional training. The research methods are theoretical: analysis (impulse, system, analytical and synthetic, inductive, deductive); synthesis (general scientific, interdisciplinary, interdisciplinary); classification, systematization, generalization; modeling. The results. The relevance and need to develop a culture of safety of future health and safety professionals under pandemic conditions during their professional training are substantiated. The significance of labor protection at work and other institutions, in social life under pandemic conditions is analyzed. The approaches that contribute to the formation of a culture of safety of future health and safety professionals (environmental, geophysical, medical and biological, algorithmic, strategic, informational, contextual, synergetic, gender, block practice) are substantiated. The considered appropriate formulas and techniques in the approaches provide an opportunity to make a dynamic management decision to effectively consolidate knowledge and skills on safety culture of future professionals under modern conditions during professional training. Conclusions. The proposed material will be of interest to teachers of higher education institutions in the field of labor protection and life safety. The research does not cover all the aspects of the problem of forming a safety culture under modern conditions. The prospect of further research requires the forming of the model that provides new principles, forms and methods of safety culture formation of future professionals in the field of labor protection.