Field Of Inflammation Research Articles

European Society of Intensive Care Medicine 14th Annual Congress, 30 September-3 October 2001, Geneva, Switzerland

The European Society of Intensive Care Medicine Annual Congress offers the opportunity for basic scientists and clinicians to share recent findings. Apart from the large number of free communications, several sessions of the congress were dedicated to state-of-the-art tutorials given by established speakers. The areas of interest of the attendees were widely distributed as usual, a reflection of the large array of so-called 'critical illnesses'. The results of clinical trials and experimental findings using recently developed drugs were presented, essentially in the fields of inflammation, sepsis, and acute lung injury. The benefits of several new compounds observed experimentally need to be confirmed clinically. The European Society of Intensive Care Medicine Congress is well established as a unique opportunity to implement and to promote a collaboration between European basic scientists and clinicians.

Leading structures of plant origin for drug development

This review summarizes the most important results of a plant screening program performed in the author's laboratory during the last 10 years. The screening program was initiated to search for new plant constituents with potential pharmacological activity in the field of inflammation in general, allergic asthma, immundeficiencies and cardiovascular diseases. The test program mainly utilised in vitro assays, and particular attention was given to the key enzymes of the prostaglandin metabolism, cellular and humoral targets of the unspecific immune system, an in vitro ACE-inhibition test system, and an in vivo plethysmographic system as an inhibitory model of bronchial obstruction. The results of structure-activity relationship studies are also described.

いわゆる下がく正中のう胞の１例

The median mandibular developmental cyst is an extremely rare lesion. It has a disputed orgin.Recently, we experienced a case of a so-called median mandibular cyst which was doubted, and was diagnosed as a non odontogenic cyst based on the results of the clinical and histopathological evaluation. It was reported.The patient was a 45-year-old man who was reffered to us for evaluation of his X-ray radiolucency of the mandibular symphysis.The history of traumas to the lower jaw was not obtained from the patient.Upon routine examination, a slightly bulging, nontender nonfluctuant, hardmass was noticed on the labial surface in the lower anterior region of the mandible.Electric pulp testing revealed that the right central incisor was nonvital and other incisors were vital.Radiographs revealed a spheral-shaped radiolucency, 2 cm in diameter, at the midline of the mandible and separated the roots of the central incisor teeth. The clinical diagnosis was a developmcntal cyst.Under local anesthesia, the cyst was enucleated in toto. In surgical findings, the cyst wall had no connection with the roots of the teeth.Histopathological examination of the cyst wall showed it was lined by a stratified cilliated epithelium and fibrous connective tissue.One area of the cyst revealed the squamous metaplasia in the field of inflammation.

STUDIES ON THE CHANGES PRODUCED BY ROENTGEN RAYS IN INFLAMED CONNECTIVE TISSUE

STUDIES ON THE CHANGES PRODUCED BY ROENTGEN RAYS IN INFLAMED CONNECTIVE TISSUE