Fibrous Mass Research Articles

Benign Brenner tumour of the ovary: CT and MRI features

To evaluate the computed tomography (CT) and magnetic resonance imaging (MRI) features of benign Brenner tumours (BBT) of the ovary. This was a retrospective two-centre study comprising 35 female patients with a definitive diagnosis of BBT at histology in whom CT and/or MRI examinations had been performed. Two experienced radiologists reviewed the CT and MRI features of 39 ovarian BBT retrospectively with consensus reading. The morphological appearance and size of each tumour were recorded. The presence or absence of calcifications within the solid portion was noted at CT. The reviewed characteristics at MRI included qualitative assessment of the signal intensity of the solid portion on diffusion sequence and contrast enhancement, compared to that of the myometrium. CT and MRI images were available for 27 and 28 lesions, respectively. Sixteen patients had both CT and MRI examinations. BBT were unilateral in 89% of patients, and 49% of lesions were solid and 51% were mixed. Calcifications were depicted at CT in 70.4% of lesions. When present, the cystic portion was multilocular in 85% of cases and corresponded to a mucinous lesion in 74% of cases. Enhancement of the solid portion at MRI was inferior or equal to that of the myometrium in 89% of cases and signal on high b-values diffusion images was deemed low or moderate in 93% of cases. The combined CT and MRI findings of a unilateral fibrous ovarian mass containing punctate calcifications often associated with a multilocular cyst suggest the diagnosis of ovarian BBT.

Description and evolution of the larynx of the Physalaemus olfersii species group, with remarks on the laryngeal anatomy of the P. cuvieri clade (Amphibia: Anura: Leiuperinae).

The anuran larynx is an organ of great evolutionary interest because it impacts male reproductive success in courtships. However, little is known about the diversity of the larynx's anatomy, evolutionary history and systematics importance. Here, we describe and compare the anatomy of the larynx of 10 Physalaemus species of the P. cuvieri clade, focusing on the P. olfersii species group. We also reconstructed the ancestral states and tested the phylogenetic signal for the anatomical features. In all the species, the larynx has a general globular shape with the arytenoid cartilages covering almost its entire dorsal surface, while the anterior process of the cricoid cartilages covers most of the ventral surface. The size of the secondary fibrous mass, the thickness of the vocal membrane, and the attachment position of the vocal membrane's free edge considerably differ among the species. Moreover, only four species of a single clade in the P. olfersii species group have the primary fibrous mass well-developed with a suspended region in the dorsolateral passage. We found a significant phylogenetic signal for all these characters. Ancestral reconstructions pointed to reduction tendencies in the thickness of the vocal membrane and the size of the secondary fibrous mass, and a shift of the ventral attachment of the vocal membrane, increasing the angle of its free edge along the phylogeny. This latter trait can diagnose the entire Physalaemus olfersii group, which has the ventral ends of the arytenoids positioned posteriorly, giving this group the steepest angles for the vocal membrane's free edge in relation to the frontal plane. Based on our results, the larynges can contribute to the Physalaemus olfersii species group's systematics and could be elucidative to understand the evolution of the genus. High levels of anatomical and bioacoustical complexity and diversity observed in the group support the expected correlation between vocal anatomy and bioacoustical signal.

Nanocellulose Extracted from Waste Polyester/Cotton Fabric by Chemical-Mechanical Separation Technology

The millions of tons of textile waste were produced every year. Most of them were made from polyester/cotton blended fabrics. The key technologies for recycling the waste blended fabrics were how to separate the blended components and then use the materials form the waste. Based on this, this research aimed to develop the technology of sustainable recycling of cotton fiber and polyester. The waste polyester/cotton blended fabric was first to cut into small pieces, then treated it with acid, and then used a grinder to crush it to separate the polyester from the cotton fiber. After the separation process, the cotton fiber was powder and the polyester fiber was fibrous mass. The components of the separated cotton samples were studied by Fourier transform infrared spectroscopy. The crystallinity of separated cotton fiber was analyzed by X-ray diffraction. The morphology of the separated cotton fiber and polyester were analyzed by scanning electron microscope. The particle size and potential of the cotton fiber after final treatment were analyzed by using the nanoparticle size and zeta potential analyzer. The results showed that the waste polyester/cotton blended fabric was successfully separated and the separated cotton fiber was successfully prepared into cotton nanocellulose for future use.

Composite polypropylene polymer materials that work in contact with raw cotton

Physicomechanical and tribotechnical properties of structural composite materials based on thermoplastic polymer and organomineral ingredients operating under friction and wear conditions during contact with pulp (raw cotton) have been investigated. The regularities of changes in the physical, mechanical and tribotechnical properties of structural composite materials during contact interaction with raw cotton were determined, the dependence of their properties on the type and content of graphite, mineral and fibrous fillers in structural composite materials was studied. It has been established that the nature and structure of fillers has a certain effect on the physical and mechanical properties of composite materials based on polypropylene. At the same time, fiber-filled compositions have the highest mechanical strength. It was also found that when mineral fillers are introduced into composite polymer materials, their coefficient of friction with raw cotton increases significantly, while the wear rate decreases, except for fillers with a plate structure (kaolin, talc), when used, a decrease in the coefficient of friction is observed. The introduction of carbon-graphite fillers into the composition of composite materials leads to a significant decrease in the coefficient of friction, temperature and static electricity charge in the friction zone with raw cotton. The introduction of fillers with a fibrous structure leads to a significant decrease in the rate of wear of the composites. It provides high strength and resistance of the material under thermomechanical action. Effective compositions of structural composite materials for work under conditions of contact interaction with fibrous mass have been developed, and their physical, mechanical and tribotechnical properties have been investigated.

First report of pulmonary disease associated with Nicoletella semolina in a horse in New Zealand

ABSTRACT Case history: A 9-year-old warmblood gelding with a history of chronic intermittent tachypnoea and dyspnoea was presented for evaluation and removal of a mass on the left side of the neck. A fibrous mass adherent to the left jugular vein developed and was removed surgically 6 weeks later, at which time the owner requested an evaluation of the cause of the persistent respiratory signs first noted on primary admission. Clinical findings and treatment: Clinical findings included coarse lung sounds on thoracic auscultation, tracheal wheeze, and an abnormal trans-tracheal aspirate. These findings, in addition to the results of ultrasonographic imaging of the thorax and transtracheal cytology, were suggestive of bacterial bronchopneumonia. Initial antimicrobial therapy included I/M 22 mg/kg procaine penicillin every 12 hours and I/V 6.6 mg/kg gentamicin sulphate every 24 hours. The horse’s clinical signs improved within 36 hours. It was discharged after 6 days, and at the owner's request antimicrobial therapy was changed to 25 mg/kg trimethoprim/sulphadimidine to be given orally every 12 hours for 10 days. One month later, the horse had recovered and there were no further complications reported by the owner except for an occasional cough while grazing Laboratory findings: Bacterial culture of transtracheal wash fluid resulted in the isolation of Nicoletella semolina as the sole organism, later confirmed by genotyping. Attempts to subculture the organism for antimicrobial susceptibility testing were unsuccessful. Diagnosis: Infectious bronchopneumonia associated with Nicoletella semolina Clinical relevance: Further work is required to determine whether N. semolina is acting as an opportunistic commensal of the equine respiratory tract or a primary pathogen. However, this article reports the first instance in New Zealand of an association between the presence of this organism and respiratory disease in a horse.

MALIGNANT MUCINOUS MYOEPITHELIOMA: A CASE REPORT

A 42-year-old female presented with asymptomatic fibrous submucosal mass that arose approximately 4 years earlier, in the left lower labial mucosa, measuring 40 mm. Aspiration showed a mucosanguinolent content. Histopathologic analysis of the incisional biopsy revealed glandular epithelial neoplasia characterized by proliferation of nests of cells in a fibrous connective tissue with areas of hyalinization. Signet ring cells, PAS-positive mucosal cells, and areas of mucus deposition were observed. Neoplastic cells presented severe cellular atypia. Immunohistochemistry was positive for p63, CK14, and CK7 and negative for SMA and S100. Ki-67 rate was 15.75%, confirming the diagnosis of malignant mucinous myoepithelioma. A head and neck surgeon performed the surgical resection of the tumor. No recurrence was observed after 5 months. Malignant mucinous myoepithelioma is a rare lesion that exhibits microscopic similarities with different entities, including other mucous-producing carcinomas, which makes its diagnosis a challenge. Support: CAPES, FAPEMIG.

Comparison of 3D and 2D late gadolinium enhancement magnetic resonance imaging in patients with acute and chronic myocarditis

We compared a fast, single breath-hold three dimensional LGE sequence (3D LGE) with an established two dimensional multi breath-hold sequence (2D LGE) and evaluated image quality and the amount of myocardial fibrosis in patients with acute and chronic myocarditis. 3D LGE and 2D LGE (both spatial resolution 1.5 × 1.5 mm2, slice-thickness 8 mm, field of view 350 × 350 mm2) were acquired in 25 patients with acute myocarditis (mean age 40 ± 18 years, 7 female) and 27 patients with chronic myocarditis (mean age 44 ± 22 years, 9 female) on a 1.5 T MR system. Image quality was evaluated by two independent, blinded readers using a 5-point Likert scale. Total myocardial mass, fibrotic mass and total fibrotic tissue percentage were quantified for both sequences in both groups. There was no significant difference in image quality between 3D und 2D acquisitions in patients with acute (p = 0.8) and chronic (p = 0.5) myocarditis. No significant differences between 3D and 2D acquisitions could be shown for myocardial mass (acute p = 0.2; chronic p = 0.3), fibrous tissue mass (acute p = 0.7; chronic p = 0.1) and total fibrous percentage (acute p = 0.4 and chronic p = 0.2). Inter-observer agreement was substantial to almost perfect. Acquisition time was significantly shorter for 3D LGE (24 ± 5 s) as compared to 2D LGE (350 ± 58 s, p < 0.001). In patients with acute and chronic myocarditis 3D LGE imaging shows equal diagnostic quality compared to standard 2D LGE imaging but with significantly reduced acquisition time.

Thermal Degradation of Cellulose Filaments and Nanocrystals.

Cellulose-derived materials, such as microcellulose and nanocellulose, are sustainable materials with a wide range of applications. Here, through a multi-analytical approach, we investigate the thermal degradation of microfibrillar cellulose filaments (CFs); acidic cellulose nanocrystals (CNC-H), containing sulfate half-ester groups on the surface; and neutralized cellulose nanocrystals (CNC-Na), where the protons are replaced by sodium ions. CFs have a simple degradation mechanism, associated with extensive dehydration, decarboxylation, and decarbonylation, and the highest thermal stability of the three (∼325 °C) despite the abundance of amorphous regions and inhomogeneous fibrous mass that make them structurally and morphologically less homogeneous than high-crystallinity CNCs. CNC-H decompose in a complex way below 200 °C, with large char fractions and evaporation of sulfur compounds at high temperatures, while sodium counterions in CNC-Na can improve the thermal stability up to 300 °C, where the pyrolysis leads to partial rehydration and formation of sodium hydroxide on the surface.

Properties and stabilization mechanism of oil-in-water Pickering emulsions stabilized by cellulose filaments

Cellulose filaments (CFs) are produced from wood-pulp fibres through solely mechanical treatment. They are inhomogeneous materials comprising both relatively large fibre fragments and fine fibrils. CFs can stabilize oil-in-water medium- and high-internal phase Pickering emulsions, where the presence of fibre fragments plays a critical role in emulsion stabilization by preventing CF fibrils from forming highly entangled structures. The emulsion properties are shown to be influenced by both the refining energy and CF concentration. CFs are distinct from cellulose nanofibrils (CNF) or microfibrillated cellulose (MFC), which flocculate and collapse owing to the entanglement of the homogeneous fibrous mass. Typically, other additives – surfactants or cellulose nanocrystals – are necessary to stabilize such emulsions. Further, lignin-containing CFs, produced from unbleached pulps, are particularly beneficial for emulsion stabilization at higher pH when the functional groups on lignin molecules are ionized. Our findings present CFs as potentially inexpensive, sustainable, and efficient emulsifiers for a wide variety of systems, from food to personal care products or engineering materials.

Influence of Separating Fibrous Seed Mass to Fractions to Quality

This article describes the fourth type of medium-fiber Hampor, currently widely used in the Surkhandarya region, the lengnth is about 160-170 mg, 171-180 mg, 181-190 mg, 191-200 mg, 201-205 mg, 206-210 mg was divided into fractions by mass of fibers, the LKM equipment was cleaned of fine and dirty particles in the laboratory of the ginnery, DL-10 was isolated from the fiber on the ginning equipment, and the physical and mechanical properties of the seeds, and 20.0 texts were made from the cotton fiber at the “Sherli” small-scale spinning device at the “Pakhtasanoat Research Center” AC. Physical and mechanical properties of the yarn, i.e. quadratic inequality of linear density, quadratic inequality by the number of twists, quadratic inequality in strength, durability, comparative shear strength, elongation at break, elongation in discontinuity was identified with the help of modern equipment and the spinning plant was able to split fibers into fractions for the production of high quality yarn, optimal versions were proposed.

Fabrication, Characterization and Moisture Absorption Analysis of Sponge Fiber-Coir Reinforced Epoxy Resin Hybrid Composite

Natural fiber reinforced composites are gaining popularity over conventional materials due its low cost, easy accessibility, non toxicity and most important feature - the biodegradability. Since broad varieties of natural fibers are available on earth, hence their merits can be incorporated in one by means of hybridization. Matured sponge gourd, which turns into a net structured fibrous mass on sun drying, is amalgamated with coconut coir as reinforcement along with epoxy resin as matrix material in a composite. The present study was carried out to explore the impact of change in weight percentages of sponge gourd fiber and coir on the mechanical properties and moisture affinity. The alkali treated fibers were turned into composites by dint of Hand Layup technique. The various mechanical properties were evaluated according to ASTM protocol. After the successful conclusion of the experiments, it was found that composite with maximum weight percentage of coir showed superlative tensile and impact strength whereas the composite with highest sponge fibre content showed maximum flexural strength. The composite with equal sponge fiber-coir weight percentage displayed lowest affinity towards moisture.

Optimization of Conditions for Synthesis of Ultrafine Silver Particles in Hemp Fiber Extract

The impact of conditions in extraction of natural admixtures (pectin compounds, hemicelluloses, and lignin) from hemp fiber during chemical modification of fibrous mass was studied. It was shown that the maximum extraction of admixtures requires increasing the temperature of fiber treatment to 100°С and the sodium hydroxide concentration to 10 g/L. Using infrared spectroscopy and potentiometric titration methods, it was proved that the increase in alkalinity of the boiling liquor leads not only to the increase in the amount of admixtures in the liquor but also to their destruction, while the complex of reducing ingredients that was formed in the liquor can act as a reductant of silver ions even under conditions of low temperatures in extraction. The kinetics of reduction of silver ions in the extract liquor was investigated. The correlation of the efficiency of the reduction of silver ions and the quantitative content of admixtures in the liquor was found. Using photon correlation spectroscopy, it was shown that reduction in an extract obtained under high alkalinity makes it possible to obtain particles of small size, not more than 30 nm. It was proved that the antimicrobial activity of synthesized sols and cellulosic materials treated with these sols against test cultures depends on the synthesis conditions.

Substantiation of Parameters of the Fibrous Material Cleaning Zone

The article provides the scheme and principle of operation of the fiber material cleaning section when using multi-faceted cylinder spikes. Theoretically studied the movement of the fibrous mass on the surface of the edge of the cylinder splitting. The numerical solution of the problem substantiates the main recommended values of the parameters of the fibrous material cleaning zone. Full-factor experiments optimized the necessary system parameters. The article also investigates the influence of the annular cylinder parameters on the cleaning efficiency of the machine based on full factorial experiments. In this case, the following ring cylinder parameters are optimized: the number of revolutions is 455 rpm, the number of faces of the multifaceted spiky is 6, and the gap between the cylinder and the mesh surface is 16 mm.

A lipomatous variant of scrotal angiomyofibroblastoma – A case report

Angiomyofibroblastoma-like tumour of the male genital tract is a rare benign mesenchymal tumour arising in the scrotum, perineum or inguinal region. It is usually seen in females of reproductive age. Clinical presentation has no pathgnomic findings. In the largest series to date, Iwasa and Fletcher1 reported 25 cases in men with the mean age being 52 years. This case report is of an 18-year-old male with a scrotal angiomyofibroblastoma that was 35 cm in maximum dimension, in the paratesticular tissue separate from testicular parenchyma. Macroscopically, the lesion was a fibrous, fatty and mucoid mass. Histologically, it showed a lobulated pattern of epithelioid and spindle cells arranged around various calibre vessels. Other differential diagnoses including myxoid liposarcoma and rhabdomyosarcoma were ruled out with the help of FISH studies for FOX 10 and PAX3. DDIT3 and FUS were negative. To date, in all open-access literature, there has only been 34 cases reported of this rare tumour, of which there is only one reported case <20 years of age; this will be the second case in the <20 age group in men. The poster will describe the clinical presentation, imaging, macroscopic findings, histology and immunohistochemistry along with a literature review. Reference1.Iwasa Y, Fletcher CD. Cellular angiofibroma: clinicopathologic and immunohistochemical analysis of 51 cases. Am J Surg Pathol 2004; 28: 1426–35.

Морфологическая структура и иммуногистохимический анализ стенок влагалища у женщин с пролапсом гениталий

to study a correlation between clinical stage of pelvic organ prolapse (POP), a histological structure and results of immunohistochemical study of the vaginal wall were evaluated. A total of 60 peri- and postmenopausal women (average age 61.9+/-8.4 years) with POP of stage II-IV, according to the POP-Q classification, or with stress urinary incontinence and cystocele of stage I-II, who undergone to surgical treatment, were included in the study. During a procedure, a biopsy from the anterior vaginal wall was taken. Depending on the stage of POP, patients was divided into two groups. In the group 1, 30 patients with stage I and II of POP were included, while group 2 included 30 women with POP of stage III and more. The control group (group 3) consisted of 20 patients without POP (mean age 63.4+/-11.0 years) who underwent a hysterectomy due to to other indications. A histological and immunohistochemical studies of vaginal wall tissue was performed in order to determine the tissue content of collagen type I and III; matrix metalloproteinases 1 and 2 (MMP-1 and MMP-2), a tissue inhibitor of metalloproteinases 1 (TIMP-1), vimentin and smooth muscle actin. In contrast to two other groups, in group 2 there were significant changes in the connective tissue. Collagen has a form of fibrous mass with areas of reduced content. In addition, scarring areas with an increase in the content of type III collagen, a decrease in the amount of type I collagen and elastic fibers with significant fragmentation, were seen. Moreover, in patients with severe POP (III-IV), degradation of collagen fibers with a decrease in connective tissue strength and elasticity was detected. Women with POP had a low ratio of type I:III collagen. Analysis of the collagen content in the vaginal wall in patients with mild POP (I-II) revealed a significant increase in the level of collagen type I (p=0.0003) and a decrease in the content of type III (p=0.045), compared to patients with more severe POP (III-IV). The level of MMP-1 and MMP-2 in women with POP was higher, than in control group by 1.7 times (p<0.05). The content of TIMP-1 in the group 1 was significantly lower by 1.5 and 2.2 times, compared to group 2 and 3, respectively. An analysis of MMP-1 and MMP-2 concentration in patients of groups 1 and 2 revealed a significant (p=0.04) decrease in their activity in severe POP (III-IV). In women of the group 2, biopsy of the vaginal wall showed that expression of vimentin and smooth muscle actin in the connective tissue was significantly higher, than in group 1 and 3 (p<0.05). Vimentin expression in the group 2 was 1.4 and 2.6 times higher than in the group 1 and 3, respectively. In the control group, the expression of these markers in the vaginal wall was minimal and focal. Our data indicate that fibrosis and degradation of the connective tissue in the vaginal wall predominate in POP, and these changes are a consequence, but not a cause of PG. The aggravation of degenerative changes in the connective tissue leads to the progression of POP.

Heterogeneous photo-Fenton oxidation of lignin of rice husk alkaline hydrolysates using Fe-impregnated silica catalysts

ABSTRACT Present work shows results of a study on heterogeneous Fenton-like degradation of lignin alkaline hydrolysates formed in the process of obtaining a fibrous mass from rice husk. Fe-impregnate biogenic amorphous silica Fe/RH-SiO2 obtained from rice husk was used as a catalyst. Using IR spectroscopy, X-ray diffraction and EDX analysis it was shown that iron(III) oxide in the form of hematite is present on the catalyst surface. Phenol was used for preliminary assessment of catalytic activity of the catalyst Fe/RH-SiO2. The degree of degradation of phenol by the UV/visible radiation/Fe/RH-SiO2/H2O2 system reaches 90%. The catalytic activity of Fe/RH-SiO2 was studied in the reaction of lignin degradation of rice husk alkaline hydrolysates under ultraviolet and visible irradiation in the presence of hydrogen peroxide. The lignin solutions with COD: Н2О2 ratios from 1:2 to 1:16 were exposure under UV irradiation for 15-minute and the subsequent lightening on sunny days between 9 am and 8 pm in April for 7 days in the presence of a catalyst and without it. The catalyst concentration was 1.0 g L−1. After that, it was found the content of phenolic compounds in the presence of a catalyst is 2–20 times lower than without it. The COD with the COD: Н2О2 = 1:16 ratio in the presence of a catalyst decreases 1.5 times as compared with the initial solution, whereas without a catalyst it increases 13 times.

Magnesium-Aluminate Spinel Fibers Obtained by the Sol-Gel Method

The sol-gel process of obtaining magnesium-aluminate spinel fibers from a fiber-forming precursor based on aluminum and magnesium polycarboxylates was studied. It was shown that in principle discrete fibers of stoichiometric spinel can be obtained by means of aerodynamic spraying. The results of surface morphology, fine structure, and phase composition studies of the fibers are presented. It is shown that the obtained fibers have a uniform and polycrystalline structure with practically no nonfibrous inclusions in the fibrous mass. The phase composition corresponds to the stoichiometry of spinel.

Flexion contracture due to cyclops lesion after bicruciate-retaining total knee arthroplasty

Flexion contracture may develop after total knee arthroplasty (TKA) and is usually associated with soft tissue contracture in the posterior compartment or hamstrings. A cyclops lesion is a soft tissue mass which can form in the anterior compartment usually after anterior cruciate ligament reconstruction and has been observed after bicruciate-retaining TKA. We have treated a patient who developed progressive loss of full extension from 0° to 20° after bicruciate-retaining TKA. A large fibrous tissue mass (cyclops lesion) was identified in the anterior compartment during arthrotomy 1 year after TKA. Excision of the mass resulted in complete resolution of the flexion contracture.

The Arylabialis Muscle of the Túngara Frog (Engystomops pustulosus).

The current functional model of the anuran larynx includes four pairs of laryngeal muscles. Their contractions do not account, however, for the behavioral control of call complexity observed in male túngara frogs (Engystomops pustulosus), which optionally add a secondary note with distinct harmonic structure to their advertisement call. Examination of the túngara frog's laryngeal morphology through dissection and resin histology has revealed that the m. dilatator laryngis is divided into two separate bundles (superficial and deep). The superficial bundle closely matches the typical description of the m. dilatator laryngis and is well positioned to open the glottis. The deep bundle is exclusively innervated by the short laryngeal nerve and has an attachment to the fibrous mass, an internal laryngeal structure necessary for complex call production. This attachment indicates a separate role for the deep bundle in controlling the complexity of the call. Based on physical separation, exclusive attachments, distinct fiber orientation, exclusive innervation, and potential action, we recognize the deep bundle of the m. dilatator laryngis as a separate muscle. We also revalidate the name m. arylabialis which had been previously used to describe it. The split of the m. dilatator laryngis into two muscles results in a laryngeal innervation pattern that closely matches that of mammals. This study identified a novel laryngeal muscle in túngara frogs, a potential mechanism for the control of call complexity, and revealed new evidence of homologies between the laryngeal structures of amphibians and mammals. Anat Rec, 2019. © 2019 American Association for Anatomy Anat Rec, 303:1966-1976, 2020. © 2019 American Association for Anatomy.

1646 Primary Colorectal Diffuse Large B-Cell Lymphoma: A Rare Presentation of a Rare Colonic Neoplasm

INTRODUCTION: Diffuse Large B Cell Lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma accounting for 25% of cases. Of those, only one third are found to have a primary extranodal source. While this is known to arise from the stomach, a colorectal primary site is exceedingly unique. We present the case of primary colonic DLBCL diagnosed in a patient admitted for hematochezia. CASE DESCRIPTION/METHODS: An 85-year-old female with coronary artery disease on aspirin and diverticulosis presented to the emergency room with acute hematochezia and left lower quadrant (LLQ) abdominal pain. She was hemodynamically stable with reproducible LLQ tenderness and rectal exam confirming bright red blood. Labs were pertinent for leukocytosis and hemoglobin of 12.1 g/dL down from a baseline of 14.4 g/dL. Contrasted abdominal CT revealed a 4.1 cm soft tissue mass in the ascending colon with extravasation of contrast consistent with active bleeding. Due to concern for a malignant bleeding etiology, interventional radiology performed CT angiography, but were unable to identify an active arterial source. The patient continued with hematochezia and was taken for urgent colonoscopy. Within the ascending colon, a 5cm non-obstructing, fibrous mass with central ulceration was identified and biopsied. Colorectal surgery was consulted; due to concern for recurrent bleeding a right hemicolectomy was performed the following day. Final pathologic diagnosis revealed primary colonic DLBCL with local lymph node involvement. PET/CT showed complete resection of disease and, through multidisciplinary shared decision making, further treatment or surveillance was not pursued. At follow up the patient is doing well without recurrent symptoms. DISCUSSION: Primary colorectal DLBCL accounts for less than 0.3% of all cancers involving the large intestine. While data is limited, the majority of patients are male between the 5th and 7th decades of life. Symptoms are nonspecific with few cases discovered due to overt bleeding. Endoscopic appearance is variable including mucosal nodularity, ulceration or a mass with or without ulceration, which can mimic adenocarcinoma. Due to the abundance of lymphoid tissue, most lesions involve the cecum and ileocecal valve. Diagnosis of primary colonic DLBCL can include local lymph node involvement, but distant nodal disease must be excluded. The mainstay of treatment is surgical resection with adjuvant chemotherapy, however, due to patient age and preference a conservative strategy was pursued.