Aiming to evaluate the effectiveness of fiber-reinforced polymer (FRP) repair on the seismic performance of blast-damaged reinforced concrete (RC) piers, the field test and numerical simulation were conducted. Firstly, a successive field explosion test, carbon FRP (CFRP) repair, and lateral cyclic loading test were performed on two 1/2-scale RC pier specimens. The test data including the incident overpressure-time histories of blast wave, damage profiles and lateral force-displacement relationships of pier specimens, etc. were comprehensively recorded and discussed. By comparing with the previous blast-damaged pier specimen, the negative maximum force and ductility of CFRP-repaired pier were increased by 97 % and 44.9 % after 1.0 kg TNT explosion, respectively. Then, an integrated numerical simulation approach based on explicit-implicit switching and full restart algorithms was proposed and validated in predicting the dynamic and quasi-static behaviors of RC piers under successive blast loading, CFRP repair, and lateral cyclic loading. Finally, a prototype RC pier was designed and the suicide vest bomb (TNT equivalence of 9 kg) specified by the Federal Emergency Management Agency was selected as the threat of contact explosion. The influences of FRP type, repair height, and number of FRP layer on restoring the seismic performance of the blast-damaged pier were further discussed. It indicates that, (i) CFRP is more effective than glass FRP and aramid FRP; (ii) increasing the repair height could not significantly improve the seismic performance of pier; (iii) the number of FRP layer has significant effect, e.g., the positive and negative maximum forces after 4-layer CFRP repair are improved by 9.4 % and 45.3 % compared to the unrepaired pier, respectively. The present study could provide a helpful reference for assessing the FRP repair effectiveness on the seismic performance of blast-damaged RC bridge piers.