Femoral Stem Design Research Articles

A comprehensive analysis of bio-inspired design of femoral stem on primary and secondary stabilities using mechanoregulatory algorithm.

The coated porous section of stem surface is initially filled with callus that undergoes osseointegration process, which develops a bond between stem and bone, lessens the micromotions and transfers stresses to the bone, proximally. This phenomenon attributes to primary and secondary stabilities of the stems that exhibit trade-off the stem stiffness. This study attempts to ascertain the influence of stem stiffness on peri-prosthetic bone formation and stress shielding when in silico models of solid CoCr alloy and Ti alloy stems, and porous Ti stems (53.8 GPa and 31.5 GPa Young's moduli) were implanted. A tissue differentiation predictive mechanoregulation algorithm was employed to estimate the evolutionary bond between bone and stem interfaces with 0.5-mm- and 1-mm-thick calluses. The results revealed that the high stiffness stems yielded higher stress shielding and lower micromotions than that of low stiffness stems. Contrarily, bone formation around solid Ti alloy stem and porous Ti 53.8 GPa stem was augmented in 0.5-mm- and 1-mm-thick calluses, respectively. All designs of stems exhibited different rates of bone formation, diverse initial micromotions and stress shielding; however, long-term bone formation was coherent with different stress shielding. Therefore, contemplating the secondary stability of the stems, low stiffness stem (Ti 53.8 GPa) gave superior biomechanical performance than that of high stiffness stems.

Classifications in Brief: The Dorr Classification of Femoral Bone.

Classifications in Brief: The Dorr Classification of Femoral Bone.

Current concepts and outcomes in cemented femoral stem design and cementation techniques: the argument for a new classification system.

Cemented implant fixation design principles have evolved since the 1950s, and various femoral stem designs are currently in use to provide a stable construct between the implant–cement and cement–bone interfaces.Cemented stems have classically been classified into two broad categories: taper slip or force closed, and composite beams or shaped closed designs. While these simplifications are acceptable general categories, there are other important surgical details that need to be taken into consideration such as different broaching techniques, cementing techniques and mantle thickness.With the evolution of cemented implants, the introduction of newer implants which have hybrid properties, and the use of different broaching techniques, the classification of a very heterogenous group of implants into simple binary categories becomes increasingly difficult. A more comprehensive classification system would aid in comparison of results and better understanding of the implants’ biomechanics.We review these differing stem designs, their respective cementing techniques and geometries. We then propose a simple four-part classification system and summarize the long-term outcomes and international registry data for each respective type of cemented prosthesis.Cite this article: EFORT Open Rev 2020;5:241-252. DOI: 10.1302/2058-5241.5.190034

Finite element analysis on the hollow porous design at the proximal end of cementless femoral prosthesis stem

The present study aims to improve the design of cementless femoral prosthesis stem and achieve better bone ingrowth and long-term stability. Four models with different directional hollow holes at the proximal end of femoral prosthesis were designed and finite element analysis was applied to calculate the magnitude of conducting force within the differently angled holes and the stress distribution of the femur and prosthesis. Holes in prostheses make no difference on the stress values of femoral inner walls. The conducting forces in models trepanned on the lateral plane were 6.60N (0° pore) and 8.40N (45° pore) while forces in models trepanned on the anterior-posterior planes were 0.45N (upper 0° pore), 0.48N (lower 0° pore) and 1.57N (upper 45° pore), 1.51N (lower 45° pore), respectively. The position and direction of hollow holes influenced the conducting force in holes but had no influence on stress values of femoral inner walls. Prostheses with one 45° hole trepanned on the lateral plane of proximal prostheses presented best in elevating conducting force.

Design of a polymeric composite material femoral stem for hip joint implant

Abstract Hip joint prosthesis are structural components that still have some challenging problems such as the interaction of physical and biological properties between the stem and the human femur. Composite materials allow to obtain high strength structures with a large variety of modulus of elasticity and favorable characteristics in the context of orthopedic implants. Therefore, the objective of this work was the development of a prosthesis model with biopolymeric matrix, namely the polyurethane (PU) derived from castor oil, reinforced with fiberglass. The implants were made of pure PU, PU with fiberglass, and PU with glass fiber and calcium carbonate. The reinforcement was constructed in the form of a core to be inserted into the hip prosthesis. The core and stem prototypes were produced using three-dimensional printing techniques, and subsequently used in the manufacture of flexible silicone molds. The results showed good mechanical potentialities of this material for orthopedics applications.

An Alternative Femoral Stem-bone Implantation Technique Using an Innovative Short Femoral Stem Endoprosthesis

Arthroplasty of the hip, for either arthritic changes or femoral neck fracture, is a common procedure in orthopedic surgery. Although the standard designs for implantation, either cemented or uncemented, are well described and studied, there are also alternative designs regarding the implantation of both prosthetic stem and cup. This paper aims to explore one such alternative design, using the screw-in technique. It has been described in past literature for uncemented fixation of both the cup and the stem, and the biomechanical principles of fixation are different from the classical methods, offering certain advantages that are insufficiently explored in current-day endoprosthesis. Also, we will be presenting an innovative femoral stem design, recently developed, that combines an uncemented screw-on technique with a cemented augmentation possibility, aimed to provide the practitioner with the advantages of a bone-preserving mini-stem design, combined with the innovative screw-in fixation technique and the versatility of the hybrid cemented/uncemented fixation method.

Direct Anterior Approach and Perioperative Fracture With a Single-Taper Wedge Femoral Component

BackgroundDespite growing interest in direct anterior approach total hip arthroplasty, perioperative femoral fracture and early aseptic loosening are increasingly recognized complications. Previous research has documented the role of surgeon experience in association with these femoral complications. The purpose of this study was to explore the relationship between femoral component design and early periprosthetic femoral complications. MethodsThis was an extension of previous work with an updated patient cohort of 5090 consecutive direct anterior primary total hip arthroplasties at a single institution with a single-taper, wedge femoral stem comprising 4 variants involving length and geometry: group 1, full-length, standard profile; group 2, full-length, reduced distal profile; group 3, short-length, standard profile; and group 4, short-length, reduced distal profile. Records were reviewed retrospectively for the incidence of early postoperative periprosthetic fracture or aseptic loosening and analyzed with regard to patient demographics and femoral stem type. ResultsThere were 42 (0.83%) periprosthetic femur complications observed in the early postoperative period. Increased age (P < .001) and female gender (P = .023) were significantly associated with incidence of femoral complications in univariate analysis, while age maintained this significant relationship in multivariate analysis (P < .001). There was a trend toward increased complication rate in patients receiving a short stem with full profile taper (1.27%, P = .0539). ConclusionDespite an overall low rate of femoral complications after direct anterior total hip arthroplasty, the risk is increased in elderly patients and females. Furthermore, femoral stem design may portend an elevated risk of these complications.

Anterior approach total hip replacement (THA) with a specialized orthopedic table

The anterior approach (AA) with a specialized table has been gaining popularity since it was taught at the first technique course in 2003. It has evolved since that time thanks to the contributions of many. Developments that are of note include new femoral stem designs to facilitate the angle of the exposure, modifications to the specialized table, increasing use of computer navigation and lastly, now it can be performed with the assistance of a mechanical mallet.

Higher periprosthetic fracture rate associated with use of modern uncemented stems compared to cemented stems in femoral neck fractures

Hemiarthroplasty is the preferred treatment for displaced femoral neck fractures in elderly patients. Recently, short tapered-wedge cementless stems have increasingly been used in this population. However, historic data has consistently shown higher rates of periprosthetic fracture with uncemented stems in hip fracture patients. This study aims to evaluate the rate of periprosthetic fracture requiring re-operation and all-cause mortality between cemented and uncemented femoral stem designs including more recent short tapered-wedge cementless stems in hip fracture patients. A retrospective chart and radiographic review of patients received bipolar hemiarthroplasty for femoral neck fractures from 2010-2016. Patients biologically (age ≥ 65 years) or physiologically (American Society of Anesthesiologists (ASA) class ≥ 3) elderly were eligible. The uncemented group was subdivided into tapered-wedge stems (a broach only system) and reamed uncemented stems. The primary outcome was periprosthetic fracture requiring re-operation. We included 657 patients in total, with 296 and 361 patients in the uncemented and cemented stem groups respectively. In the uncemented group there were 197 tapered-wedge and 99 reamed uncemented stems. There was a significantly higher rate of periprosthetic fracture requiring re-operation in the uncemented group (3.0% vs. 0.6%) ( p ≤ 0.05). There were no significant differences in rates of all-cause mortality, infection or all-cause re-operation. Compared to modern uncemented femoral stem designs, cemented stems yield lower rates of periprosthetic fracture requiring re-operation, without increasing risk of all-cause mortality. Tapered-wedge stems had similar rates of re-operation due to periprosthetic fracture as reamed uncemented stems.

The tridimensional geometry of the proximal femur should determine the design of cementless femoral stem in total hip arthroplasty.

Using a cementless femoral stem in total hip arthroplasty (THA), optimal filling of the proximal femoral metaphyseal volume (PFMV) and restoration of the extramedullary proximal femoral (PF) parameters (i.e., femoral offset (FO), neck length (FNL), and head height (FHH)) constitute key goals for optimal hip biomechanics, functional outcome, and THA survivorship. However, almost 30% of mismatch between the PF anatomy and implant geometry of the most widely implanted non-modular cementless femoral stem has been demonstrated in a computed tomography scan (CT scan) study. Therefore, this anatomic study aimed to evaluate the relationship between the intra- and extramedullary PF parameters using tridimensional CT scan reconstructions. One hundred fifty-one CT scans of adult healthy hips were obtained from 151 male Caucasian patients (mean age = 66 ± 11years) undergoing lower limb CT scan arteriography. Tridimensional PF reconstructions and parameter measurements were performed using a corrected PF coronal plane-defined by the femoral neck and diaphyseal canal longitudinal axes-to avoid influence of PF helitorsion and femoral neck version on extramedullary PF parameters. Independently of the femoral neck-shaft angle, the PFMV was significantly and positively correlated with the FO, FNL, and FHH (r = 0.407 to 0.420; p < 0.0001). This study emphasized that the tridimensional PF geometry measurement in the corrected coronal plane of the femoral neck can be useful to determine and optimize the design of a non-modular cementless femoral stem. Particularly, continuous homothetic size progression of the intra- and extramedullary PF parameters should be achieved to assure stem fixation and restore anatomic hip biomechanics.

A long-term comparative study between two different designs of cemented stems: Distal-cylindrical versus distal-taper

IntroductionThe aim of this study was to calculate the wear rate of highly cross-linked polyethylene (HXLPE) and investigate long-term clinical and radiographic outcomes related to two femoral stem designs, the distal-cylindrical (DC) and distal-taper (DT) stems. Materials and methodsOutcomes for the DC and DT stems were evaluated in 110 patients, who underwent total hip arthroplasty using an HXLPE socket, over a 5-year follow-up period. There were 56 hips (53 patients) in the DC group and 60 hips (57 patients) in the DT group. Clinical outcomes were measured using the Japanese Orthopaedic Association (JOA) score and radiographic changes. Polyethylene wear rate was calculated using a computer software. ResultsThe mean follow-up period was 135.7 and 124.0 months for the DC and DT groups, respectively. Both stem designs improved hip function. On radiographic assessment, osteolysis around the tip of the stem was more frequent in the DC than in the DT group. Three cases of aseptic loosening of the stem were identified in the DC group, and no cases were identified in the DT group. The 10-year stem survival, using aseptic loosening as the primary endpoint, was 94.1% and 100% for the DC and DT groups, respectively (p = 0.06). The polyethylene wear rate was comparable for both stem groups. ConclusionBetter clinical outcomes were obtained with the DT stem than with the DC stem regardless of the equivalent polyethylene wear rate for the two designs. The DC shape of the stem may increase the risk of aseptic loosening.

Up to 10-year follow-up of the Symax stem in THA: a Danish single-centre study.

The design of the cementless Symax-HA femoral stem is based on geometrical analysis of human femoral anatomy to optimise the fit within the femur. The stem combines an anatomical proximal section enabling a metaphyseal anchorage with a straight distal section. This results in an improved proximal load transfer. We aimed to determine the overall survival of total hip arthroplasty (THA) in patients operated at our institution with the Symax stem. Secondly, we investigated the cause of revision for patients having THA including the Symax stem. The study is a registry study with results from a single centre, Vejle Hospital. From the Danish Hip -Arthroplasty Registry, we identified all THAs operated with the Symax stem. The primary outcome was revision. The secondary outcomes were aseptic loosening, periprosthetic fracture, and all other causes for revision. In total, 1,055 THAs were performed in 875 patients. The median 6.5-year survival rate was 97.5% (95% confidence interval [CI]: 96.6%-98.3%). 29 THAs had undergone revision due to the following causes: periprosthetic fracture (n = 11); aseptic loosening of the cup (n = 1); infection (n = 5); dislocation (n = 10); and component failure (n = 2). There was no revision due to aseptic loosening of the stem. From the Danish Hip Arthroplasty Registry, we identified the overall 6.5-year survival rate to be 95% for cementless THAs. In the present study, the Symax stem has a median 6.5-year survival rate at 97.5% (96.6%-98.3%). No revisions were due to aseptic loosening but the stem had a relative high prevalence of periprosthetic fractures.

Impact of Femoral Stem Design on Failure After Anterior Approach Total Hip Arthroplasty

BackgroundAn increased rate of complications related to femoral component failure has been described with less invasive total hip arthroplasty (THA). This study evaluated the incidence of femoral complications associated with the direct anterior approach for THA. MethodsRetrospective review was performed of the initial 1120 consecutive patients who underwent direct anterior THA by 2 surgeons. ResultsA total of 899 patients (80.3%) had a 2-year follow-up (range, 2-8 years). Complications within 90 days occurred in 20 patients (1.8%): 10 calcar fractures, 1 greater trochanter fracture, 1 canal perforation, 3 hematomas, 2 dislocations, 2 superficial, and 1 deep infection. Nine patients (1%) underwent revision: 5 for aseptic femoral loosening (0.55%), 1 for periprosthetic joint infection, 1 for dislocation, 1 for hip flexor irritation, and 1 for a damaged polyethylene liner.Of the 5 patients with aseptic femoral loosening, 3 had a short, mediolateral tapered stem, 1 cemented stem, and 1 S-ROM stem placed to bypass a canal perforation. There were no revisions for aseptic loosening in the collared, fully hydroxyapatite (HA)-coated compaction broached or triple tapered proximal fit and fill stem designs (70.6% of all stems). Revision rate for femoral loosening was significantly higher for tapered wedge over HA-coated, compaction broached stems (P < .005). ConclusionPain and function improved predictably with a 0.55% rate of femoral loosening at 2-year follow-up. Among collared, fully HA-coated and triple taper fit and fill femoral stems, there were no instances of revision for aseptic loosening vs 3 in the short stem, collarless mediolateral tapered group.

Anchoring and resulting primary stability of a kinked compared to a straight uncemented femoral stem.

The number of revision hip arthroplasties being performed is growing and implantation of a cementless stem has become established as the gold standard. For producing a primary stability, the press-fit procedure is the method of choice, but also can be achieved by multiple-point impactions. Specific femoral stems should follow the anatomical shape and provide a more extensive anchorage. The objective of this study was to evaluate the type, localization of the impaction and resulting primary stability of two different femoral revision stem designs (kinked vs. straight) after implantation via an endofemoral approach in the case of more extensive defects of the proximal femur. Cementless stems of two different designs were implanted in synthetic femurs. The specimens were analyzed by CT and tested considering axial/torsional stiffness and migration resistance in a servohydraulic testing machine. The present data do not show any significant differences between the two endofemorally implanted conical stems in contact area or in biomechanics with regard to migration and axial or torsional stiffness, despite having different designs. The location, type and length of the stem anchorage are not only influenced by the kinked or straight design, but in particular also by the surgical approach. Also in the case of an extensive proximal bone defect, in the endofemoral approach, both a conical and a three-point anchorage occur. Here, the length of the conical anchorage determines the primary stability and should be at least 55mm.

Current methods of preventing aseptic loosening and improving osseointegration of titanium implants in cementless total hip arthroplasty: a review.

Hip osteoarthritis is the most common joint disorder, and is represented by a degenerative process, resulting in pain and functional impairment. If conservative treatment for hip osteoarthritis fails, the only remaining option is hip arthroplasty. Despite good survival of implants, loosening of components is the most common complication. This leads to revision surgeries, which are technically demanding, expensive, and result in a low satisfaction rate. Uncemented hip replacements require proper osseointegration for increased survival. Physical characteristics of implants include biocompatibility, Young’s modulus of elasticity, strength, and corrosion resistance, and each influence fixation of implants. Moreover, implant surface treatments, pore size, pore density, and femoral stem design should be appropriately selected. Patients’ optimization of obesity, osteoporosis, cardiovascular disease, psychotic disorders, and smoking cessation are associated with a higher survival of implants. Surgical factors, such as approach, drilling and rasping, acetabular bone coverage, acetabular cup positioning, and implant size, also affect survival of implants. Avoiding drugs, which may impair osseointegration of implants, and having an appropriate rehabilitation protocol are important. Future directions include anabolic and anti-catabolic bone-acting drugs to enhance osseointegration of implants. Comprehensive knowledge of the factors mentioned above is important for preventing aseptic loosening, with important socioeconomic consequences.

Influence of collars on the primary stability of cementless femoral stems: A finite element study using a diverse patient cohort

For cementless femoral stems, there is debate as to whether a collar enhances primary stability and load transfer compared to collarless designs. Finite Element (FE) analysis has the potential to compare stem designs within the same cohort, allowing for subtle performance differences to be identified, if present. Subject-specific FE models of intact and implanted femora were run for a diverse cohort (21 males, 20 females; BMI 16.4-41.2 kg/m2 , age 50-80 yrs). Collared and collarless versions of Corail® (DePuy Synthes, Warsaw, IN) were sized and positioned using an automated algorithm that aligns the femoral/stem axes, preserves the head-center location, and maximizes metaphyseal fit. Joint contact and muscle forces simulating peak forces in level gait and stair climbing and were scaled to the body mass and applied to each subject. Three failure scenarios were assessed: Potential for peri-prosthetic fibrous tissue formation (stem micromotion), potential for peri-prosthetic bone damage (equivalent strains), and calcar bone remodeling (changes in strain-energy density). Comparisons were performed using paired t-tests. Only subtle differences were found (mean 90th percentile micromotion: Collared = 86 µm, collarless = 92.5 µm, mean 90th percentile interface strains: Collared = 733 µϵ, collarless = 767 µϵ, and similar remodeling stimuli were predicted). The slight differences observed were small in comparison with the inter-patient variability. Statement of clinical significance: Our results suggest that the presence/absence of a collar is unlikely to substantially alter the bone-implant biomechanics nor the initial mechanical environment. Hence, a collar is likely to have minimal clinical impact. Analysis using different femoral stem designs is recommended before generalising these findings. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:1185-1195, 2018.

Development and in vitro validation of a simplified numerical model for the design of a biomimetic femoral stem.

Dense and stiff metallic femoral stems implanted into femurs for total hip arthroplasties produce a stress shielding effect since they modify the original load sharing path in the bony structure. Consequently, in the long term, the strain adaptive nature of bones leads to bone resorption, implant loosening, and the need for arthroplasty revision. The design of new cementless femoral stems integrating open porous structures can reduce the global stiffness of the stems, allowing them a better match with that of bones and provide their firm fixation via bone ingrowth, and, thus reduce the risk of implantation failure. This paper aims to develop and validate a simplified numerical model of stress shielding, which calculates the levels of bone resorption or formation by comparing strain distributions on the surface of the intact and the implanted femurs subjected to a simulated biological loading. Two femoral stems produced by laser powder-bed fusion using Ti-6Al-4V alloy are employed: the first is fully dense, while the second features a diamond cubic lattice structure in its core. The validation consists of a comparison of the numerically calculated force-displacement diagrams, and displacement and strain fields with their experimental equivalents obtained using the digital image correlation technique. The numerical models showed reasonable agreement between the force-displacement diagrams. Also, satisfactory results for the correlation analyses of the total displacement and equivalent strain fields were obtained. The stress shielding effect of the implant was assessed by comparing the equivalent strain fields of the implanted and intact femurs. The results obtained predicted less bone resorption in the femur implanted with the porous stem than with its dense counterpart.

Proximal femoral anatomy and collared stems in hip arthroplasty: is a single collar size sufficient?

BackgroundEven if the benefits of collars are unclear, they remain widely used, in several femoral stem designs. This study aimed to determine whether collar size should be proportional to hip dimensions and morphology. The hypothesis was that the collar should be larger for greater stem sizes and for varus femoral necks.MethodsComputed Tomography scans of 204 healthy hips were digitally analysed and manually templated to determine principle dimensions, appropriate stem size and model, as well as cortical distance at the femoral calcar (ideal collar size).ResultsUnivariable analysis revealed that cortical distance was moderately correlated with mediolateral offset (r = 0.572; p < 0.0001) and stem model (r = 0.520; p < 0.0001). Cortical distance was weakly correlated with head diameter (r = 0.399; p < 0.0001), stem size (r = 0.200; p = 0.017), and patient gender (r = 0.361; p < 0.0001). Multivariable analysis confirmed that stem model (p < 0.0001) and head diameter (p = 0.0162) are directly correlated to cortical distance.ConclusionWe found that cortical distance along the femoral calcar is directly correlated with the model of the stem implanted (‘standard’ or ‘varus’) and with the head diameter. This cortical distance indicates optimal collar size, which would grant maximum calcar coverage without prosthetic overhang. Collar size should be proportional to the size of the operated hip, and should be larger for ‘varus’ stem models than for ‘standard’ stem models.

Femoral stem incorporating a diamond cubic lattice structure: Design, manufacture and testing.

The current total hip prostheses with dense femoral stems are considerably stiffer than the host bones, which leads to such long-term complications as aseptic loosening, and eventually, the need for a revision. Consequently, the lifetime of the implantation does not match the lifetime expectation of young patients. A femoral stem design featuring a porous structure is proposed to lower its stiffness and allow bone tissue ingrowth. The porous structure is based on a diamond cubic lattice in which the pore size and the strut thickness are selected to meet the biomechanical requirements of the strength and the bone ingrowth. A porous stem and its fully dense counterpart are produced by laser powder-bed fusion using Ti-6Al-4V alloy. To evaluate the stiffness reduction, static testing based on the ISO standard 7206-4 is performed. The experimental results recorded by digital image correlation are analyzed and compared to the numerical model. The numerical and experimental force-displacement characteristics of the porous stem show a 31% lower stiffness as compared to that of its dense counterpart. Moreover, the correlation analysis of the total displacement and equivalent strain fields allows the preliminary validation of the numerical model of the porous stem. Finally, the analysis of the surface-to-volume and the strength-to-stiffness ratios of diamond lattice structures allow the assessment of their potential as biomimetic constructs for load-bearing orthopaedic implants.

Retrieval evidence of impingement at the third articulation in contemporary dual mobility cups for total hip arthroplasty

PurposeWe aimed to assess polyethylene liners of retrieved hips of one design of a dual mobility (DM) cup liner and two designs of femoral stems to better understand the role of femoral stem design on polyethylene impingement.MethodsThis was a case-control study involving 70 retrieved highly cross-linked polyethylene (X3) liners used with ABGII (n = 35) and Rejuvenate (n = 35) stems (Stryker). All polyethylene liners were assessed for evidence of rim deformation and the damage quantified using metrology methods.ResultsA total of 80% of polyethylene liners paired with ABGII necks had macroscopic evidence of neck impingement resulting in a raised lip whilst 23% of liners paired with Rejuvenate necks had evidence of a raised lip (p < 0.0001). The height of the raised rims of the DM cups paired with ABGII necks had a median (range) of 139 μm (72–255). The height of the raised rims of the DM cups paired with Rejuvenate necks had a median (range) of 52 μm (45–90) (p < 0.0001).ConclusionOur new findings from retrieved dual mobility bearings showed that polyethylene liner rim deformation resulting from impingement with the femoral neck occurs in early in-human function, is circumferential in distribution, and is affected by the stem neck design. We recommend the use of highly polished and non-edged neck designs when used in conjunction with DM cups.