Objective: to identify the factors influencing the level of infrastructure development created in the framework of public-private partnership projects in the regions of the Russian Federation.Methods: general scientific methods of cognition were used in the process of research; methods of system analysis, which make it possible to comprehend the patterns of infrastructure development, the optimal ways and methods of managing partner projects; statistical and structural-functional analysis, enabling to identify the dependence on internal and external factors; methods of generalization and grouping.Results: public-private partnership is one of the mechanisms that have proven useful for the development of infrastructure of regions and municipalities. The article emphasizes the importance of PPP projects in the Russian practice, as well as the need for further research to improve its effectiveness. On the basis of the regions’ ranking by the level of public-private partnership development, presented by the “PPP Development Center” Association, the analysis of various factors was carried out that allow determining the place of a region in this ranking. Also, the analysis results are presented, which show the implementation of projects to create an innovative PPP infrastructure in the Republic of Tatarstan, as a result of which the thesis about the impact of the selected factors on the development of PPP was confirmed. The main activities contributing to the development of PPP in the Republic of Tatarstan are identified, and recommendations to improve its efficiency are formulated.Scientific novelty: based on the data of the ranking of the Russian Federation subjects, a regression model was made, describing the relationship between the level of public-private partnership development in the region and such factors as the proximity of the Russian Federation subject to the capital, the unemployment rate in the region and the number of large profitable enterprises in its territory - potential subjects of public-private partnership. The conditions of effective development of regional projects in the sphere of public-private partnership are revealed and systematized.Practical significance: the results can be used as recommendations for the development of regional infrastructure in the framework of public-private partnership projects.