Fast Cycle Research Articles

Diurnal transcriptome landscape of a multi-tissue response to time-restricted feeding in mammals

Time-restricted feeding (TRF) is an emerging behavioral nutrition intervention that involves a daily cycle of feeding and fasting. In both animals and humans, TRF has pleiotropic health benefits that arise from multiple organ systems, yet the molecular basis of TRF-mediated benefits is not well understood. Here, we subjected mice to isocaloric ad libitum feeding (ALF) or TRF of a western diet and examined gene expression changes in samples taken from 22 organs and brain regions collected every 2h over a 24-h period. We discovered that TRF profoundly impacts gene expression. Nearly 80% of all genes show differential expression or rhythmicity under TRF in at least one tissue. Functional annotation of these changes revealed tissue- and pathway-specific impacts of TRF. These findings and resources provide a critical foundation for future mechanistic studies and will help to guide human time-restricted eating (TRE) interventions to treat various disease conditions with or without pharmacotherapies.

Thermal stress influence on the long-term performance of fast-charging paraffin-based thermal storage

• Fast-charging cycle leads to a higher thermal stress and hysteresis losses. • 10,000 cycle assessment reveals the deterioration on thermal performances. • The storage efficiency decreases 12.7% after 10,000 fast charging cycles. • Isothermal phase transition provides a better power rate and duration. The present study evaluates the impact of charging speeds on the long-term performance of paraffin-based thermal energy storage (TES) up to 10,000 actual thermal cycles. Paraffin and form-stable phase change material (FSPCM) is used as the reference materials. The FSPCM is made of paraffin (80 wt%) and high-density polyethylene (HDPE, 20 wt%). The thermal cycling treatment is applied to the samples using slow (1 °C/min), normal (5 °C/min) and fast-charging cycles (10 °C/min). Performance assessment is conducted using an active thermal storage model. According to the assessment, thermal stress and hysteresis effect occur severely after 10,000 fast-charging cycles. It disrupts the heat transfer process, reducing the power and charging rate. Scanning electron microscope (SEM) shows the void formation for paraffin which correspond to a lower efficiency (62.5%) than FSPCM (66.6%). The presence of HDPE reduces the impact of the fast-charging effect on paraffin. The SEM micrograph for FSPCM indicates that a chemi-crystallization leads to phase-separation between paraffin and HDPE. It helps to maintain the charging and discharging duration after 10,000 fast-charging cycles. Furthermore, the decrement of melting enthalpy of FSPCM (5.5%) is much lower than paraffin (12.7%). Hence, FPSCM maintains the storage capacity after 10,000 fast-charging cycles at a sufficient level. The multi-step transition and power curve during the charging/discharging cycle are discussed in detail within the article. Further improvement can be taken to minimize the performance degradation of fast-charging paraffin-based TES by compositing paraffin to withstand thermal stress or modifying the system operation after a certain fast-charging cycle.

Dual-Channel EtherCAT Control System for 33-DOF Humanoid Robot TOCABI

Multi-axis actuation robotics systems comprising many joints with a floating base require more stability and safety than fixed robots and thus require more considerations. In this paper, we describe the implementation of a real-time EtherCAT control system for the TOCABI humanoid robot with 33 degrees of freedom (DOFs) is described. The focus is on the development of a high-performing EtherCAT MainDevice, which enables control of the robot’s high DOF at fast communication cycles. We also explore the use of a dual-channel EtherCAT MainDevice as a redundancy mechanism to handle communication disruptions and show that this configuration reduces the burden on the communication network and increases the communication cycle, leading to good real-time performance. To demonstrate the advantages of the system, we examine the performance of the EtherCAT communication and evaluate the impact of RTnet on real-time performance, demonstrating that a high-performing EtherCAT MainDevice having hard real-time capabilities can be established using open-source software. The results of this work demonstrate the potential of using dual channels in EtherCAT MainDevice configurations and utilizing open-source software to implement low-cost EtherCAT MainDevice systems. The paper’s contribution to the field is its indication of developing stable robot systems with high DOF, which require hard real-time capability, even with open-source software.

Development of adjusted nuclear data library for fast reactor application

In Japan, development of adjusted nuclear data library for fast rector application based on the cross-section adjustment method has been conducted since the early 1990s. The adjusted library is called the unified cross-section set, which is an ABBN-type group constant set with 70-group energy structure. The first version was developed in 1991 and is called ADJ91. After that, ADJ98, ADJ2000, ADJ2000R, and ADJ2010 were constantly developed. For instance, ADJ2010 was developed based on JENDL-4.0, which provides covariance data needed to apply the cross-section adjustment method, by using 488 integral experimental data acquired in typical fast reactor systems. ADJ2010 has been used as the standard cross-section set for nuclear design in the fast reactor cycle technology development project (FaCT) and the succeeding fast reactor projects. In parallel, the integral experimental data were further expanded to improve the design prediction accuracy of the core loaded with MA and/or degraded Pu. Using the additional integral experimental data, development of the next version of ADJ2017 was started in 2017. In 2022, the latest unified cross-section set AJD2017R was developed based on JENDL-4.0 by using 619 integral experimental data. An overview of the latest version with a review of previous ones will be shown. On the other hand, the latest Japanese evaluated nuclear data library JENDL-5 was released at the end of 2021. In the development of JENDL-5, some of the integral experimental data used in ADJ2017R were explicitly utilized in the nuclear data evaluation. However, this is not reflected in the covariance data. This situation needs to be considered when developing a next version of the unified cross-section set based on JENDL-5. Preliminary adjustment calculation based on JENDL-5 is performed using C/E (calculation/experiment) values simply evaluated by a sensitivity analysis. The preliminary result of the JENDL-5-based adjustment will be also discussed.

Growth Evaluation of Red Tilapia (Oreochromis spp) Under Different Cycles of Fasting And Re-Feeding

Feed restriction through fasting is a widely recommended feed management strategy in aquaculture, where this strategy is believed to have a positive effect on fish growth performance. This study aims to evaluate the growth performance of red tilapia in various cycles of fasting and re-feeding. The activity was carried out at Research Institute Fish Breeding from August to November 2020 . The research method used was experimental with 5 treatments with 4 replications, namely control (fish were fed daily), then the fasting treatment was S7 (7 days of fasting), S14 (14 days of fasting), S21 (21 days of fasting) and S28 (28 fasting day) followed by refeeding until the end of maintenance. Maintenance was carried out for 90 days in a concrete tub measuring 2x1m3 with a stocking density of 28 fishes / unit. During the rearing period the fish were fed satiation three times a day. The results showed that there was a decrease in growth along with the increase of the fasting period, but there was a trend of increasing growth after re-feeding with over compensatory growth in treatment S7 and partial compensatory growth in treatments S14 and S21. Likewise, the value of the condition factor and the hepatosomatic index during the fasting period decreased, but after feeding, the values were not different from those of fish fed continuously.

Improvement of Fire Resistance and Mechanical Properties of Glass Fiber Reinforced Plastic (GFRP) Composite Prepared from Combination of Active Nano Filler of Modified Pumice and Commercial Active Fillers

Glass fiber reinforced plastic (GFRP) composites have great potential to replace metal components in vehicles by maintaining their mechanical properties and improving fire resistance. Ease of form, anti-corrosion, lightweight, fast production cycle, durability and high strength-to-weight ratio are the advantages of GFRP compared to conventional materials. The transition to the use of plastic materials can be performed by increasing their mechanical, thermal and fire resistance properties. This research aims to improve the fire resistance of GFRP composite and maintain its strength by a combination of pumice-based active nano filler and commercial active filler. The nano active filler of pumice particle (nAFPP) was obtained by the sol-gel method. Aluminum trihydroxide (ATH), sodium silicate (SS) and boric acid (BA) were commercial active fillers that were used in this study. The GFRP composite was prepared by a combination of woven roving (WR) and chopped strand mat (CSM) glass fibers with an unsaturated polyester matrix. The composite specimens were produced using a press mold method for controlling the thickness of specimens. Composites were tested with a burning test apparatus, flexural bending machine and Izod impact tester. Composites were also analyzed by SEM, TGA, DSC, FT-IR spectroscopy and macro photographs. The addition of nAFPP and reducing the amount of ATH increased ignition time significantly and decreased the burning rate of specimens. The higher content of nAFPP significantly increased the flexural and impact strength. TGA analysis shows that higher ATH content had a good contribution to reducing specimen weight loss. It is also strengthened by the lower exothermic of the specimen with higher ATH content. The use of SS and BA inhibited combustion by forming charcoal or protective film; however, excessive use of them produced porosity and lowered mechanical properties.

Evaluation of LiNiO2 with minimal cation mixing as a cathode for Li-ion batteries

The electric vehicle (EV) market has grown tremendously in recent years, and is driving the development of lithium-ion batteries (LIBs) for energy storage. To meet the demand for high-energy–density and low-cost LIBs, Co-free and Ni-rich cathodes (e.g., LiNiO2; LNO) and Si anodes are being investigated. However, drawbacks of LNO, such as cation mixing, processing challenges, and safety risks significantly limit its commercialization. Increasing the oxygen partial pressure (pO2) during calcination of LNO has been shown to maintain its structural order and electrochemical performance. However, the mechanism by this observation is not well understood. In this research, three pO2 conditions were applied during the calcination of LNO cathodes. The calcination pO2 affects the sub-surface of LNO rather than the bulk region. Synchrotron spectroscopy and in-situ pressure analysis confirmed that Ni2+ and excess Li are present on the sub-surface of the LNO processed at the lowest pO2. Increasing the pO2 decreases the off-stoichiometry of LNO by providing additional oxygen to compensate for oxygen loss, especially at the sub-surface. A detailed mechanism by which the calcination pO2 affects LNO is proposed. An LIB with the LNO cathode calcined at the highest pO2 had a high initial capacity of 239.8 mA h g−1 (93.4 %), excellent fast charging cycle retention of half-cell and full cell at 55 °C, little gas evolution during cycling, and almost no weight change during storage in air. This calcining strategy prevents the cation mixing limitation of LNO, taking it one step closer to future EV application.

Circadian disruption: from mouse models to molecular mechanisms and cancer therapeutic targets.

The circadian clock is a timekeeping system for numerous biological rhythms that contribute to the regulation of numerous homeostatic processes in humans. Disruption of circadian rhythms influences physiology and behavior and is associated with adverse health outcomes, especially cancer. However, the underlying molecular mechanisms of circadian disruption-associated cancer initiation and development remain unclear. It is essential to construct good circadian disruption models to uncover and validate the detailed molecular clock framework of circadian disruption in cancer development and progression. Mouse models are the most widely used in circadian studies due to their relatively small size, fast reproduction cycle, easy genome manipulation, and economic practicality. Here, we reviewed the current mouse models of circadian disruption, including suprachiasmatic nuclei destruction, genetic engineering, light disruption, sleep deprivation, and other lifestyle factors in our understanding of the crosstalk between circadian rhythms and oncogenic signaling, as well as the molecular mechanisms of circadian disruption that promotes cancer growth. We focused on the discoveries made with the nocturnal mouse, diurnal human being, and cell culture and provided several circadian rhythm-based cancer therapeutic strategies.

Enhanced redox cycle of Fe3+/Fe2+ on Fe@NC by boron: Fast electron transfer and long-term stability for Fenton-like reaction

In this work, Fe@NC/B material is successfully synthesized and in-situ supported on the surface of amorphous boron (B) using a simple pyrolysis method. The interface between Fe species and B is improved by introducing N-doped carbon (NC) layers as intermediate, fast electron transfer from B to Fe@NC can therefore be achieved, thus could promote the fast redox cycle of Fe3+/Fe2+. The obtained material can therefore activate peroxymonosulfate (PMS) effectively to degrade Bisphenol A (BPA), a fast degradation rate and a very long lifetime in a continous tubular reactor are realized. Moreover, experiments and DFT calculation indicate that Fe2+ containing species are the dominated active sites, while the exposed B atoms and structure defect of B can also activate PMS directly to produce SO4•− and 1O2 species for BPA degradation. In addition, boric acid is the oxidation product of B, which can be dissolved into the aqueous solution and expose fresh B species again for PMS activation. The combination of B with Fe@NC provide novel materials for long term PMS activation, thus could promote the real application of persulfates on an industrial scale.

Fast differential scanning calorimetry to mimic additive manufacturing processing: specific heat capacity analysis of aluminium alloys

Eutectic AlSi12, commonly used in casting and in additive manufacturing, is investigated with Fast Differential Scanning Calorimetry to determine the impact of different cooling rates from the liquid state upon the apparent specific heat capacity on subsequent heating. A heat flow correction strategy is developed and refined for the reliable and precise measurement of sample heat flow using chip sensors and assessed by the evaluation of results on pure (99.999%) aluminium. That strategy is then applied to the study of the AlSi12 eutectic alloy, and rate-dependent perturbations in the measured apparent specific heat capacity are discussed in terms of Si supersaturation and precipitation. Several cooling rates were implemented from − 100 to − 30,000 K s−1, and subsequent heating ranged from + 1000 to + 30,000 K s−1. After rapid cooling, a drop in AlSi12 apparent specific heat capacity is found on heating above ~ 400 °C; even at rates of + 10,000 K s−1, a result which has high relevance in metal additive manufacturing where similarly fast temperature cycles are involved. The Literature data, temperature modulated DSC and CALPHAD simulations on the heat capacity of AlSi12 are used to provide comparative context to the results from Fast Differential Scanning Calorimetry.

OP70 Gaps In The Evaluation Of Clinical Decision Support Software (CDSS): Interviews With Australian Policymakers

IntroductionClinical Decision Support Software (CDSS) can improve the quality and safety of care by providing patient-specific diagnostic and treatment recommendations. However, robust evaluation is required to ensure that the recommendations provided are clinically valid, up-to-date, and relevant to a specific clinical context. Most evaluation studies assess CDSS performance from the perspective of end-user requirements. But only occasionally is CDSS subject to stringent pre- and post-market evaluation, making it difficult to determine the safety and quality in practice. This study aimed to assess CDSS evaluation in Australia to identify gaps in evaluation approaches.MethodsWe conducted 11 semi-structured interviews with different policymakers from committees involved in digital health activities in Australia. Data were thematically analyzed using both theory-based (deductive) and data-driven (inductive) approaches.ResultsOur findings indicated that evaluating CDSS as a purely technical intervention has overly narrowed the assessment of benefits and risks by inadequately capturing the sociotechnical environment. Existing evaluation methods, adopting a static view of the implemented system, cannot discern the impact of the dynamic clinical environment and rapidly evolving technology on CDSS performance. The timeframe of evaluation studies are also incongruent with fast software upgrade cycles, with clinical practices and software potentially changing by the time evaluation is complete. The regulation of software as a medical device depends on the intended use. CDSS are exempt from regulation because they only ‘produce advice’; however, this ignores the fact that they can transition to specifying a diagnosis and treatment after a software update. There is no framework for continuous post-market monitoring, and this is especially important when a CDSS algorithm can change and impact on patient management.ConclusionsThe sociotechnical environment is a significant factor influencing the impact of CDSS on clinical practice, therefore evaluation approaches must acknowledge the dynamic nature of clinical and organizational contexts. Pragmatic and data-driven methodologies are required for CDSS evaluation that acknowledge the evolving landscape of clinical practice and its relationship to technology.

Prediction of Morphology Distribution within Injection Molded Parts Obtained with Fast Cavity Heating Cycles: Effect of Packing Pressure

Prediction of Morphology Distribution within Injection Molded Parts Obtained with Fast Cavity Heating Cycles: Effect of Packing Pressure

Effective DevSecOps Implementation: A Systematic Literature Review

Adopting DevOps means increased collaboration between development and operations teams and faster release cycles through a shift to automation. Using Dev Ops brings with it several advantages in the development of software. Security, however, is often neglected in DevOps due to the fast release cycle. Therefore Dev Sec Ops has emerged as an extension to DevOps that attempts to integrate security with Dev Ops practices, which is not without its challenges. DevOps, and by extension Dev Sec Ops, represents a significant change in the culture, tooling, and processes used in software development. Therefore, when implementing DevSecOps, teams and their organizations need to be aware of the challenges it brings and how to address those challenges for a DevSecOps implementation to be effective. Literature on DevSecOps exists that outlines practices and principles to do this. This paper uses a grounded theory approach to do a systematic literature review of academic literature to find the factors that contribute to an effective DevSecOps implementation. It attempts to reconcile the challenges of DevSecOps with ways of mitigating them and the advantages that a DevSecOps implementation can bring. The paper thus outlines methods of effectively implementing DevSecOps as described in academic literature.

Regulating DNA-Hybridization Using a Chemically Fueled Reaction Cycle.

Molecular machines, such as ATPases or motor proteins, couple the catalysis of a chemical reaction, most commonly hydrolysis of nucleotide triphosphates, to their conformational change. In essence, they continuously convert a chemical fuel to drive their motion. An outstanding goal of nanotechnology remains to synthesize a nanomachine with similar functions, precision, and speed. The field of DNA nanotechnology has given rise to the engineering precision required for such a device. Simultaneously, the field of systems chemistry developed fast chemical reaction cycles that convert fuel to change the function of molecules. In this work, we thus combined a chemical reaction cycle with the precision of DNA nanotechnology to yield kinetic control over the conformational state of a DNA hairpin. Future work on such systems will result in out-of-equilibrium DNA nanodevices with precise functions.

Analytical Study of Sources of Textile Waste for Its Upcycling

In recent years, there have been increasing concerns in the disposal of textile waste around the globe. The growth of textile markets not only depends on population growth but also depends on economic and fashion cycles. The fast fashion cycle in the textile industry has led to a high level of consumption and waste generation. Textile waste is a material that's supposedly unworkable for its original purpose by the proprietor. Textile waste is produced in every phase of the cloth manufacturing process like spinning, weaving, dyeing, finishing, garment manufacturing and indeed at the consumer end.The textile industry has two sections, the study has been conducted one is the textile industry and second is the apparel industry. This paper consists of information about the textile industry, textile waste, garments waste. Also, the reason behind this problem has been discussed in this paper and how it can be resolved for the least harm to the environment. Various methods to reduce textile waste are also discussed such as Prolonging the life of your clothes, preventing textile waste starts with buying less, Repair, Upcycle, Swap, Donate, Recycle and Buy less and make it last. Data was collected from the study that has been conducted through the secondary sources by studying the research paper related to textile waste titles. 5 Garments Export Houses were interviewed for this research paper. A brief understanding of upcycling of textile waste and discarded garments is discussed in this paper.

Capture-bonding Super Assembly of Nanoscale Dispersed Bimetal on Uniform CeO2 Nanorod for the Toluene Oxidation.

Elimination of VOCs by catalytic oxidation is an important technology. Here, a general synergistic capture-bonding superassembly strategy was proposed to obtain the nanoscale dispersed 5.8% PtFe3 -CeO2 catalyst, which showed a high toluene oxidation activity (T100 =226 °C), excellent catalytic stability (125 h, >99.5%) and a good water resistance ability (70 h, >99.5%). Through the detailed XPS analysis, oxygen cycle experiment, hydrogen reduction experiment, and in-situ DRIFT experiment, we could deduce that PtFe3 -CeO2 had two reaction pathways. The surface adsorbed oxygen resulting from PtFe3 nanoparticles played a dominant role, due to the fast cycling between the surface adsorbed oxygen and oxygen vacancy. In contrast, the lattice oxygen resulting from CeO2 nanorods played an important role due to the relationship between the toluene oxidation activity and the metal-oxygen bonding energy. Furthermore, DFT simulation verified Pt sites were the dominant reaction active sites during this reaction.

Modification of Battery Separators via Electrospinning to Enable Lamination in Cell Assembly

To meet the requirements of today’s fast-growing Li-ion battery market, cell production depends on cheap, fast and reliable methods. Lamination of electrodes and separators can accelerate the time-consuming stacking step in pouch cell assembly, reduce scrap rate and enhance battery performance. However, few laminable separators are available on the market so far. This study introduces electrospinning as a well-suited technique to apply thin functional polymer layers to common battery separator types, enabling lamination. The method is shown to be particularly appropriate for temperature resistant ceramic separators, for which stable interfaces between separator and electrodes were formed and capacity fading during 600 fast charging cycles was reduced by 44%. In addition, a straightforward approach to apply the method to other types of separators is presented, including separator characterization, coating polymer selection, mechanical tests on intermediates and electrochemical validation in pouch cells. The concept was successfully used for the modification of a polyethylene separator, to which a novel fluoroelastomer was applied. The stability of the electrode/separator interface depends on the polymer mass loading, lamination temperature and lamination pressure, whereas poorly selected lamination conditions may cause damage on the separator. Appropriate adhesion force of 8.3 N/m could be achieved using a polymer loading as low as 0.25 g/m2. In case separator properties, coating polymer, morphology of the fibrous coating and lamination conditions are well adjusted to each other, the implementation of electrospinning and lamination allows for faster, more flexible and robust pouch cell production at comparable or better electrochemical cell behaviour.

Association of Core Muscle Endurance with Weekly Workout Time, Speed, and the Symmetry of Frontal Core Motion during Indoor Walking and Cycling

This study investigated the factors that influence core muscle endurance, i.e., the symmetry of frontal core motion during indoor walking and cycling, the symmetry of lateral core muscle endurance, the symmetry of the hip abductor strength, the weekly workout time and fast walking and cycling speeds, while controlling for gender. Seventy-nine healthy young adults participated in this study. In a regression analysis, the core muscle endurance time was the dependent variable. The independent variables were the symmetry of frontal core motion (measured using a wireless earbud sensor during walking and cycling), the symmetry of side plank time and of hip abductor strength, the weekly workout time and fast walking and cycling speeds. In the multiple regression analysis, weekly workout time, fast walking speed, symmetry of frontal core motion during fast cycling and symmetry of lateral side plank time predicted core muscle endurance (adjusted R2 = 0.42). Thus, clinicians and fitness personnel should consider the association of core muscle endurance with the symmetry of frontal core motion during cycling and the symmetry of side plank holding time, as well as with the weekly workout time and a fast walking speed, when designing core muscle exercise programmes.

Glioblastoma-derived extracellular vesicle subpopulations following 5-aminolevulinic acid treatment bear diagnostic implications.

Liquid biopsy is a minimally invasive alternative to surgical biopsy, encompassing different analytes including extracellular vesicles (EVs), circulating tumour cells (CTCs), circulating tumour DNA (ctDNA), proteins, and metabolites. EVs are released by virtually all cells, but at a higher rate by faster cycling, malignant cells. They encapsulate cargo native to the originating cell and can thus provide a window into the tumour landscape. EVs are often analysed in bulk which hinders the analysis of rare, tumour-specific EV subpopulations from the large host EV background. Here, we fractionated EV subpopulations in vitro and in vivo and characterized their phenotype and generic cargo. We used 5-aminolevulinic acid (5-ALA) to induce release of endogenously fluorescent tumour-specific EVs (EVPpIX ). Analysis of five different subpopulations (EVPpIX , EVCD63 , EVCD9 , EVEGFR , EVCFDA ) from glioblastoma (GBM) cell lines revealed unique transcriptome profiles, with the EVPpIX transcriptome demonstrating closer alignment to tumorigenic processes over the other subpopulations. Similarly, isolation of tumour-specific EVs from GBM patient plasma showed enrichment in GBM-associated genes, when compared to bulk EVs from plasma. We propose that fractionation of EV populations facilitates detection and isolation of tumour-specific EVs for disease monitoring.

Self-supported hollow-Co3O4@CNT: A versatile anode and cathode host material for high-performance lithium-ion and lithium-sulfur batteries

Inferior specific capacity and sluggish redox kinetics are the most stubborn problems lithium-ion and lithium-sulfur batteries (LIBs and LSBs) are facing, respectively. Here we report a facile fabrication of self-supported hollow Co 3 O 4 @carbon nanotubes on carbon cloth (H-Co 3 O 4 @CNT/CC) through a mild pyrolysis-oxidation process. The additive- and binder-free H-Co 3 O 4 @CNT/CC shows excellent electrochemical performances as both LIBs and LSBs electrodes. As a robust integrated anode for LIBs, the areal capacities are 2.72 mAh cm −2 at the current density of 0.5 C over 1000 cycles. While as a durable cathode host for LSBs, favorable areal capacities of 2.37 mAh cm −2 are maintained with a low capacity decay of 0.11 % per cycle at the sulfur loading of 6 mg cm −2 and current density of 1 C after 400 cycles. Electrochemical technology, ex situ Raman spectroscopy and DFT calculations are performed to comprehensively analyze H-Co 3 O 4 @CNT/CC via thermodynamics and kinetics. It is demonstrated that the hierarchically hollow interior structure, strong adsorb ability of Co 3 O 4 toward polysulfides and three-dimensional (3D) inter-connected conductive carbon framework are responsible for the high areal capacity, fast redox kinetics and cycling durability. The synergistic effect of different components and structures of hollow-Co 3 O 4 @CNT, which have internal hollow structure, incorporation of Co 3 O 4 into elastic buffering framework and high porosity, contributes greatly to the superior electrochemical performances in terms of high areal capacity, good rate capability and ultralong cycling stability. • The integrated electrode possesses the merits of hollow nanostructured Co 3 O 4 and 3D inter-connected conductive network. • Electrochemical technology and DFT calculations are performed to comprehensively analyze H-Co 3 O 4 @CNT/CC. • H-Co 3 O 4 @CNT/CC delivers high areal capacities of 2.72 mAh cm -2 after 1000 cycles at 0.5 C as anode.