AbstractNonwovens have wide application areas due to their advantageous properties like low cost, high production efficiency, and tuneable properties. They are mostly used for disposable products. Combining bicomponent fiber spinning with hydroentanglement method is one of the innovative methods to obtain nonwovens for durable applications. On the other hand, ultrasonic welding is an alternative assembling method for disposable products made of low weight nonwovens. In this study, the ultrasonic weldability of relatively heavier weight and thicker nonwoven fabrics made of polyester: polyamide bicomponent microfilaments were examined in order to combine the advantages of nonwovens and ultrasonic welding. Relatively higher thickness and weight, and also fiber composition of the nonwoven fabrics were compelling effects of the study that drove the motivation. Overall 60 samples were produced using five nonwoven fabrics with varying unit masses and 12 selected ultrasonic welding types. Seam strength and strain assessments were supported with stereomicroscope and visual inspections in evaluating the welds. Results showed that despite having thick seam lines up to 1.6 mm, successful welded seams could be obtained. Depending on the welding parameters, seam lines of some samples exhibited waviness, color changes, and deformations but these situations did not drastically affect the seam strength of samples.