Extensor Carpi Radialis Muscles Research Articles

Acute effects of local vibration inducing tonic vibration reflex or illusion of movement on maximal wrist force production.

Local vibration (LV) mainly stimulates primary afferents (Ia) and can induce a tonic vibration reflex (TVR) and an illusion of movement. This study aimed to evaluate the effect of these two phenomena on maximal voluntary isometric contraction (MVIC) capacity. LV (80 Hz) was applied to the wrist flexor muscles in two randomized experiments for 6 min. LV conditions were adjusted to promote either TVR (visual focus on the vibrated wrist) or ILLUSION [hand hidden, visual focus on electromyographic activity of the flexor carpi radialis muscle (FCR)]. Mechanical and electromyographic (EMG) responses of the FCR and extensor carpi radialis muscles were recorded during MVIC in flexion and extension and during electrically evoked contractions at supramaximal intensity. Measurements were performed before (10 min and just before) and after (0 and 30 min) LV protocol. An increase in FCR EMG was observed during LV in the TVR condition (+340%) compared with the illusion condition (P = 0.003). In contrast, the movement illusion was greater in the ILLUSION condition (assessed through subjective scales) (P = 0.004). MVIC was reduced in flexion only after the TVR condition ([Formula: see text], all P < 0.034). Moreover, the decrease in force was correlated with the amount of TVR recorded on the FCR muscle (r = -0.64, P = 0.005). Although potentiated doublets of each muscle did not evolve differently between conditions, a decrease was observed between the first and the last measure. In conclusion, when conducting research to assess maximal strength, it is necessary to have better control and reporting of the phenomena induced during LV.NEW & NOTEWORTHY The maximal force production of the vibrated muscle is reduced after 6 min of LV only in TVR condition. Furthermore, the amount of TVR is negatively correlated with this force decrease. When measuring the effects of LV on maximal force production, it is important to control and report any phenomena induced during vibration, such as TVR or movement illusion, which can be achieved by recording EMG activity of vibrated muscle and quantifying illusion.

Insulin-like growth factor-1 infusion in preterm piglets does not affect growth parameters of skeletal muscle or tendon tissue.

Prematurity has physical consequences, such as lower birth weight, decreased muscle mass and increased risk of adult-onset metabolic disease. Insulin-like growth factor 1 (IGF-1) has therapeutic potential to improve the growth and quality of muscle and tendon in premature births, and thus attenuate some of these sequalae. We investigated the effect of IGF-1 on extensor carpi radialis muscle and biceps brachii tendon of preterm piglets. The preterm group consisted of 19-day-old preterm (10 days early) piglets, treated with either IGF-1 or vehicle. Term controls consisted of groups of 9-day-old piglets (D9) and 19-day-old piglets (D19). Muscle samples were analysed by immunofluorescence to determine the cross-sectional area (CSA) of muscle fibres, fibre type composition, satellite cell content and central nuclei-containing fibres in the muscle. Tendon samples were analysed for CSA, collagen content and maturation, and vascularization. Gene expression of the tendon was measured by RT-qPCR. Across all endpoints, we found no significant effect of IGF-1 treatment on preterm piglets. Preterm piglets had smaller muscle fibre CSA compared to D9 and D19 control group. Satellite cell content was similar across all groups. For tendon, we found an effect of age on tendon CSA, and mRNA levels of COL1A1, tenomodulin and scleraxis. Immunoreactivity for elastin and CD31, and several markers of tendon maturation, were increased in D9 compared to the preterm piglets. Collagen content was similar across groups. IGF-1 treatment of preterm-born piglets does not influence the growth and maturation of skeletal muscle and tendon.

Restoration of coherent reach-grasp-pull movement via sequential intraneural peripheral nerve stimulation in rats

Objective. Peripheral nerve stimulation (PNS) has been demonstrated as an effective way to selectively activate muscles and to produce fine hand movements. However, sequential multi-joint upper limb movements, which are critical for paralysis rehabilitation, has not been tested with PNS. Here, we aimed to restore multiple upper limb joint movements through an intraneural interface with a single electrode, achieving coherent reach-grasp-pull movement tasks through sequential stimulation. Approach. A transverse intrafascicular multichannel electrode was implanted under the axilla of the rat’s upper limb, traversing the musculocutaneous, radial, median, and ulnar nerves. Intramuscular electrodes were implanted into the biceps brachii (BB), triceps brachii (TB), flexor carpi radialis (FCR), and extensor carpi radialis (ECR) muscles to record electromyographic (EMG) activity and video recordings were used to capture the kinematics of elbow, wrist, and digit joints. Charge-balanced biphasic pulses were applied to different channels to recruit distinct upper limb muscles, with concurrent recording of EMG signals and joint kinematics to assess the efficacy of the stimulation. Finally, a sequential stimulation protocol was employed by generating coordinated pulses in different channels. Main results. BB, TB, FCR and ECR muscles were selectively activated and various upper limb movements, including elbow flexion, elbow extension, wrist flexion, wrist extension, digit flexion, and digit extension, were reliably generated. The modulation effects of stimulation parameters, including pulse width, amplitude, and frequency, on induced joint movements were investigated and reach-grasp-pull movement was elicited by sequential stimulation. Significance. Our results demonstrated the feasibility of sequential intraneural stimulation for functional multi-joint movement restoration, providing a new approach for clinical rehabilitation in paralyzed patients.

Upper Extremity Muscle Activation during Drive Volley and Groundstroke for Two-Handed Backhand of Female Tennis Players.

Drive volley is one of the essential backhand stroke technique trends seen in recent women's tennis competitions. Although movements of the drive volley and groundstroke are similar, activation of the internal muscles vary due to different incoming ball conditions. Most previous studies only focused on the groundstroke, however. The current study investigates the different muscle activation patterns in the upper extremity muscle during the two-handed backhand drive volley as well as the groundstroke for female tennis players. Ten elite female tennis players were measured in the muscle activation of the flexor carpi radialis (FCR), extensor carpi radialis (ECR), biceps brachii (BB), and triceps brachii (TB) from both upper extremities. Racket-head speed at impact, swing duration of each phase, and racket-head average velocity in both strokes were also recorded. Significant differences were found between the drive volley and groundstroke in the velocity profile of racket tip, swing duration of each phase (preparation, early follow-through, and late follow-through), activation patterns of upper extremity muscles, and flexor/ extensor ratios of wrist and elbow in both upper extremities. Different racket trajectory strategies were also observed between the two strokes, with greater horizontal racket velocity recorded in the groundstroke but greater vertical velocity in the drive volley. ECR and TB muscle activation during the drive volley preparation phase was greater than the groundstroke when completing a quicker backswing. In the early acceleration phase, the greater FCR leading arm activation in the drive volley assisted wrist stabilization in preparation for impact. In the late follow-through phase, less TB leading arm activity and higher ECR trailing arm activity in the drive volley showed more forward compression movement in racket contact with the ball. As it is essential for the drive volley to complete a quicker backswing and to increase shot efficiency at the end of the forward movement, coaches should consider the two strokes' muscle activation and technique differences to enhance specific techniques and fitness training programs.

Monosynaptic facilitation of flexor digitorum superficialis motoneurons mediated by Group Ia afferents from the extensor carpi radialis in humans.

Wrist position is known to affect the grip strength. We focused on the spinal reflex arc, which would support the movement, and investigated the effects of low-threshold afferents from the extensor carpi radialis (ECR) on the excitability of the flexor digitorum superficialis (FDS) motoneurons using the post-stimulus time-histogram (PSTH) and electromyogram-averaging (EMG-A) methods. Electrical conditioning stimulation of an intensity below the motor threshold was applied to the radial nerve branch innervating the ECR. In the PSTH study, changes in the firing probability of single motor units after electrical conditioning stimulation were investigated in seven subjects. An early and significant peak (increase in the firing probability: facilitation) was recorded for 36/60 FDS motor units. The remaining 24 motor units did not show any effects. Weak mechanical conditioning stimulation of the ECR muscle belly induced a similar peak. The central latency of the facilitation was equivalent to that of the homonymous monosynaptic facilitation. In the EMG-A study, changes in the rectified and averaged electromyograms of FDS induced by conditioning stimulation were examined in 12 subjects. An early and significant peak (facilitation) was induced by both electrical and mechanical conditioning stimulations. The facilitation decreased after withdrawal of the vibration to the ECR muscle belly. The facilitation was never induced by cutaneous nerve stimulation in the PSTH and EMG-A studies. These findings suggest that Group Ia afferents from the ECR increase the excitability of FDS motoneurons through a monosynaptic path in the spinal cord. These reflex arcs likely facilitate hand grasping movements.

Monosynaptic facilitation of motoneurons innervating intrinsic hand muscles mediated by group Ia afferents from the extensor carpi radialis in humans

The projection pattern of low‐threshold afferents from the extensor carpi radialis (ECR) to motoneurons supplying intrinsic hand muscles was investigated using the post‐stimulus time‐histogram (PSTH) and electromyogram‐averaging (EMG‐A) methods. Electrical conditioning stimulation was applied to the radial nerve branch innervating the ECR. In the PSTH study, changes in the firing probability of single motor units following the stimulation were examined. An early and significant peak (facilitation) was induced in the motoneurons innervating the muscles, but the facilitation was induced infrequently. The central latency of the facilitation was equivalent to that of homonymous facilitation through monosynaptic path in the spinal cord. In the EMG‐A study, changes in the rectified and averaged electromyograms following the conditioning stimulation were examined. An early and significant peak (facilitation) was also induced. The facilitation disappeared after withdrawal of the vibration to the ECR muscle belly. Cutaneous nerve stimulation overlaying ECR never induced such facilitation in the PSTH and EMG‐A studies. These findings suggest that monosynaptic facilitation mediated by group Ia afferents of ECR to the motoneurons supplying intrinsic hand muscles exists in humans, but the connection seems to be weak. This weakness might allow manipulatory movements of the hand.

Evidence That Brain-Controlled Functional Electrical Stimulation Could Elicit Targeted Corticospinal Facilitation of Hand Muscles in Healthy Young Adults

ObjectivesBrain-computer interface (BCI)–controlled functional electrical stimulation (FES) has been used in rehabilitation for improving hand motor function. However, mechanisms of improvements are still not well understood. The objective of this study was to investigate how BCI-controlled FES affects hand muscle corticospinal excitability. Materials and MethodsA total of 12 healthy young adults were recruited in the study. During BCI calibration, a single electroencephalography channel from the motor cortex and a frequency band were chosen to detect event-related desynchronization (ERD) of cortical oscillatory activity during kinesthetic wrist motor imagery (MI). The MI-based BCI system was used to detect active states on the basis of ERD activity in real time and produce contralateral wrist extension movements through FES of the extensor carpi radialis (ECR) muscle. As a control condition, FES was used to generate wrist extension at random intervals. The two interventions were performed on separate days and lasted 25 minutes. Motor evoked potentials (MEPs) in ECR (intervention target) and flexor carpi radialis (FCR) muscles were elicited through single-pulse transcranial magnetic stimulation of the motor cortex to compare corticospinal excitability before (pre), immediately after (post0), and 30 minutes after (post30) the interventions. ResultsAfter the BCI-FES intervention, ECR muscle MEPs were significantly facilitated at post0 and post30 time points compared with before the intervention (pre), whereas there were no changes in the FCR muscle corticospinal excitability. Conversely, after the random FES intervention, both ECR and FCR muscle MEPs were unaffected compared with before the intervention (pre). ConclusionsOur results demonstrated evidence that BCI-FES intervention could elicit muscle-specific short-term corticospinal excitability facilitation of the intervention targeted (ECR) muscle only, whereas randomly applied FES was ineffective in eliciting any changes. Notably, these findings suggest that associative cortical and peripheral activations during BCI-FES can effectively elicit targeted muscle corticospinal excitability facilitation, implying possible rehabilitation mechanisms.

Músculos cráneo-laterales del antebrazo del mapache cangrejero (Procyon cancrivorus) y una revisión comparativa con otros carnívoros

ABSTRACT The crab-eating raccoon Procyon cancrivorus (Cuvier, 1798) is a species of the order Carnivora and family Procyonidae with a geographical distribution in Central and South America. Although crab-eating raccoons use scansorial locomotion, they also have aquatic habits, displaying greatly developed skills when handling their food. This species can frequently be found in wildlife care centers due to injuries caused by domestic dogs, humans, and car collisions. Having knowledge of the species’ gross anatomy and anatomical bases is imperative to perform the most appropriate medical and surgical procedures. Thus, the objective of this investigation was to analyze the interspecific and intraspecific differences of the craniolateral forearm muscles of Procyon cancrivorus. Gross dissections were performed in four specimens describing the origin, insertion, shape, innervation, and arterial supply of the craniolateral forearm muscles. There is a constant and well development of brachioradialis muscle comparatively to that described in strictly cursorial species; the extensor carpi radialis muscle has two bellies that are fused proximally; the extensor digitorum communis muscle can also extend the tendon to the digit I as an anatomical variant, and the extensor digiti I and II muscle also extends the tendon to digit III. All are innervated by the deep branch of the radial nerve, and their arterial supply is mainly by the radial collateral, cubital transverse, and cranial interosseous arteries. The anatomical characteristics observed in this study complement the previous descriptions for Procyon cancrivorus, and the anatomical variants found in this species can also be in other carnivorans. Thus, the intraspecific anatomical variations of the digital extensor muscles in P. cancrivorus are phylogenetic traits that can occur as a common pattern or as anatomical variants in other species of the order Carnivora.

High concurrent validity between digital and analogue algometers to measure pressure pain thresholds in healthy participants and people with migraine: a cross-sectional study

BackgroundPressure pain thresholds (PPTs) are commonly assessed to quantify mechanical sensitivity in various conditions, including migraine. Digital and analogue algometers are used, but the concurrent validity between these algometers is unknown. Therefore, we assessed the concurrent validity between a digital and analogue algometer to determine PPTs in healthy participants and people with migraine.MethodsTwenty-six healthy participants and twenty-nine people with migraine participated in the study. PPTs were measured interictally and bilaterally at the cephalic region (temporal muscle, C1 paraspinal muscles, and trapezius muscle) and extra-cephalic region (extensor carpi radialis muscle and tibialis anterior muscle). PPTs were first determined with a digital algometer, followed by an analogue algometer. Intraclass correlation coefficients (ICC3.1) and limits of agreement were calculated to quantify concurrent validity.ResultsThe concurrent validity between algometers in both groups was moderate to excellent (ICC3.1 ranged from 0.82 to 0.99, with 95%CI: 0.65 to 0.99). Although PPTs measured with the analogue algometer were higher at most locations in both groups (p < 0.05), the mean differences between both devices were less than 18.3 kPa. The variation in methods, such as a hand-held switch (digital algometer) versus verbal commands (analogue algometer) to indicate when the threshold was reached, may explain these differences in scores. The limits of agreement varied per location and between healthy participants and people with migraine.ConclusionThe concurrent validity between the digital and analogue algometer is excellent in healthy participants and moderate in people with migraine. Both types of algometer are well-suited for research and clinical practice but are not exchangeable within a study or patient follow-up.

The effect of arm support and control modes on muscle fatigue, eye fatigue, and posture changes in mobile game use among young adults

AbstractBackgroundThe popularity of mobile gaming among adults has raised concerns about the adverse health effects of localized muscle and eye fatigue. This study aimed to investigate how arm support and mobile game control characteristics affect muscle and eye fatigue, and postural changes.MethodsTwelve subjects, ages 21–24 years old, were recruited to play a mobile game for 60 min. Participants used two postures (sitting with and without arm support) and two game control modes (touch and rocker). Electromyography measured the abductor pollicis brevis, the upper trapezius, and the extensor carpi radialis muscles. A motion capture system was employed to assess postural changes. Self‐reported fatigue was measured using Borg's scale and Heuer's questionnaire.ResultsArm support had a significant effect on muscle fatigue and posture, including a lower rating of perceived exertion in the shoulder (p &lt; .05) and arm (p &lt; .01), an increase in neck and trunk forward flexion between 22% and 34%, an increase in forearm bearing angle of 97.63%, and a decrease in upper arm bearing angle of 25.94% in the group without arm support. Blink for touch mode was 10.57% higher than for rocker mode.ConclusionArm support was effective in reducing fatigue in the arm and shoulder, but not in the hand. Compared to rocker mode, touch mode increased the visual burden and accelerated visual fatigue. This study provides an understanding of the association between playing mobile games and fatigue, which can help prevent muscle and visual fatigue in mobile gaming.

Anatomical Variations of the Extrinsic Musculature of Thumb

Anatomical variations are commonly encountered during human cadaver dissections. Some of these variations are never discovered unless there is an underlying injury that requires attention. For conceivable clinical and rehabilitation treatments, anatomical modifications may have implications on function therefore it is imperative to report them. This case series depicts the anatomical inconsistency in the muscles and tendons of the extrinsic musculature of the thumb in three human specimens. During a cadaver dissection in physical therapy anatomy course, various anatomical variations were found in three human cadaveric specimens. Cadaver 1 exhibited a new muscle with a split tendon near the distal posterolateral radius. The author uncovered the supplementary muscle between the Extensor Pollicis Longus (EPL) and Extensor Pollicis Brevis muscles. Cadaver 2 had two other extrinsic tendons inserted at the thumb. The Extensor Digitorum provided an extra tendon to the pollicis; a similar insertion as the EPL was recognised. In cadaver 3 an extra muscle belly was observed within the tendon of the abductor pollicis longus. The other muscle variation was near the distolateral attachment at the base of the first metacarpal joint, between the abductor pollicis brevis and extensor carpi radialis muscles. Understanding the diverse anatomical arrangements could prove beneficial for surgeons and those involved in rehabilitating upper extremities. A detailed understanding of the forearm structural anatomy and anomalies is essential to comprehend the function and movements when lesions affect the normal biomechanics within teaching and clinical environments.

Biomechanical risk factors associated with distal upper extremity musculoskeletal disorders in endoscopists performing colonoscopy

Endoscopists experience upper extremity musculoskeletal injuries. The primary aim of this study was to compare distal upper extremity biomechanical risk factors during colonoscopy with established risk thresholds. Secondary aims were to determine which subtasks during colonoscopy are associated with the greatest risk and to evaluate an intervention to reduce risks. Twelve endoscopists performed 2 to 4 colonoscopies while thumb pinch force and forearm muscle loads of extensor carpi radialis (ECR) and flexor digitorum superficialis (FDS) muscles were collected. Peak exertion values were analyzed using amplitude probability distribution functions. An endoscope support device was evaluated during simulated colonoscopy (n= 8). Mean endoscopist age was 42.3 years; 67% were men. Peak thumb pinch force exceeded risk thresholds for pinch force (10 N) and percent of time spent in forceful pinch for all colonoscopy subtasks. Peak ECR and FDS muscle activity exceeded the action limit (10% maximum voluntary contraction [MVC]) in both forearms. Peak left FDS, left ECR, and right ECR activity exceeded the threshold limit value (>30% MVC). Peak left FDS and ECR activity were significantly greater during insertion than during withdrawal (P< .05). Peak right FDS and ECR activity were significantly greater during right colon insertion compared with withdrawal (P< .05). The endoscope support device reduced left ECR muscle activity (P= .02). Thumb pinch forces and time spent in forceful pinch indicate high-risk exposures during colonoscopy. Left wrist extensor muscle activity exceeded established thresholds with the greatest risk occurring during insertion. An endoscope support device reduced loads to the left wrist extensors.

Does anodal trans-cranial direct current stimulation of the damaged primary motor cortex affects wrist flexor muscle spasticity and also activity of the wrist flexor and extensor muscles in patients with stroke?: a Randomized Clinical Trial.

Spasticity is a common symptom in stroke survivors. This study is double-blinded, sham-controlled randomized, clinical trial with three parallel arms. The aim of the study was to investigate the effects of anodal trans-cranial direct current stimulation (a-tDCS) over the damaged primary motor cortex (M1) on spasticity of the wrist flexor and also the activity of wrist flexor and extensor muscles in sub-acute stroke patients. This study was performed on 32 stroke patients. The patients are assigned to three groups (intervention, sham, and control). All participants in the first two groups received 20-min concurrent M1 a-tDCS or sham tDCS and functional electrical stimulation (FES) for 10 sessions (5 sessions per week), while participants in control group were given only 20-min FES for 10 sessions. Modified Ashworth scale of wrist flexors and also electromyography (EMG) activity of flexor carpi radialis (FCR) and extensor carpi radialis (ECR) were recorded before, immediately, and 1 month after the interventions. A significant reduction was shown in the MAS and EMG activity of FCR muscle at passive rest position of the wrist, immediately and 1 month after the intervention in M1 a-tDCS compared to sham and control groups (p < 0.001). Also, the EMG activity of FCR and ECR muscles during active wrist flexion and extension increased immediately and 1 month after intervention in M1 a-tDCS compared to the other groups, respectively (p < 0.001). M1 a-tDCS can significantly decrease the spasticity of wrist flexor muscle and also increase the wrist flexor and extensor muscles activity in stroke patients during active flexion and extension.

Understanding the dual-task costs of walking: a StartReact study

The need to perform multiple tasks more or less simultaneously is a common occurrence during walking in daily life. Performing tasks simultaneously typically impacts task performance negatively. Hypothetically, such dual-task costs may be explained by a lowered state of preparation due to competition for attentional resources, or alternatively, by a ‘bottleneck’ in response initiation. Here, we investigated both hypotheses by comparing ‘StartReact’ effects during a manual squeezing task under single-task (when seated) and dual-task (when walking) conditions. StartReact is the acceleration of reaction times by a startling stimulation (a startling acoustic stimulus was applied in 25% of trials), attributed to the startling stimulus directly releasing a pre-prepared movement. If dual-task costs are due to a lowered state of preparation, we expected trials both with and without an accompanying startling stimulus to be delayed compared to the single-task condition, whereas we expected only trials without a startling stimulus to be delayed if a bottleneck in response initiation would underlie dual-task costs. Reaction times of the manual squeezing task in the flexor digitorum superficialis and extensor carpi radialis muscle were significantly delayed (approx. 20 ms) when walking compared to the seated position. A startling acoustic stimulus significantly decreased reaction times of the squeezing task (approx. 60 ms) both when walking and sitting. Dual-task costs during walking are, therefore, likely the result of lowered task preparation because of competition for attentional resources.

Abductor Pollicis Longus distal muscle belly variation in a male human cadaver

BackgroundTypically, five muscles of the posterior forearm intersect the wrist joint and contribute tendons to the first two digits.PurposeDepict the anatomical variation in the muscles and tendons of the extrinsic musculature of the thumb in one human cadaver.MethodsOne specimen was dissected and reported in this work. During dissection, an extra muscle belly was found embedded within the tendon of abductor pollicis longus. This variation was discovered near the distolateral attachment site at the base of the first metacarpal joint.ResultsThe additional muscle belly is located between abductor pollicis brevis and extensor carpi radialis muscles. Typically, the proximal muscle belly originates at the posterior proximal half of the ulna and middle one‐third of the radius inserting at the typical site of attachment, lateral aspect of the base of the first metatarsal, via the tendon. However, the tendon continues distally to a second muscle belly embedded within the distolateral one‐third of the abductor pollicis longus tendon where the attachment site can be found at the traditional lateral aspect of the base of the first metacarpal bone.ConclusionThe extrinsic extensors of the thenar region in this cadaver had an additional distal muscle belly embedded within the distal (extra) portion of the tendon differing from the standard structures. Knowledge of this additional structure may help medical professionals understand possible functional differences among individuals with this morphological variation.Picture of thumb with extra tendon anatomy variation.Figure 1

Image Diagnosis in Extensor Tendons Injuries in the Radiocarpal Region in Horses

Background: Soft tissue injuries are common in sport horses, especially those involving tendons, with few current reports in the literature on the diagnosis of extensor injuries, especially with regard to ultrasound characteristics, being essential for the diagnosis of these injuries. The objective of the study is to characterize the clinical signs and the alterations of images, especially ultrasound, in the diagnosis of these lesions of the dorsal radiocarpal region, through case reports of horses seen at the Medical Clinic of Large Animals of the Federal University of Campina Grande (MCLA/UFCG), Patos-PB, Brazil.Cases: The study includes five “vaquejada” competitions horses, of which two were active and the others were away from the sport before the onset of the problem, with injuries to the extensor tendons in the radiocarpal region. Two of the animals had involvement of the common digital extensor muscle tendon (CDEMT), with acute and chronic tenosynovitis, and three with involvement of the extensor carpi radialis muscle tendon (ECRMT), presenting acute tendonitis, septic tenosynovitis and rupture, all of traumatic etiology, except for one whose cause has not been determined. On physical examination, the affected tendon was noticeable in three cases, and two had other injuries associated with the tendons. Bone alteration in the radiographic examination was observed in two cases, however, one of them related to another disease in the radiocarpal palmar region. Ultrasound images, performed in all cases, showed different characteristics and degrees of the involvement of the tendon and its sheath.Discussion: The scarcity of current reports of extensor tendon injuries in horses can be attributed to the fact that they do not suffer as much overload or effect from biomechanics compared to flexor tendons, in addition to being an area of little soft tissue covering these tendons. Although the involvement of the extensor tendons is more frequent in the pelvic limbs, due to lacerations, the occurrence of lesions in the dorsal radiocarpal region may be related to excess flexion, being easily susceptible to trauma to solid objects. The specific clinical examination, associated with a well-explored anamnesis, can allow us to locate the lesion and achieve a presumptive diagnosis. In three cases, tendon injuries were noticeable on inspection and palpation, important points to guide the diagnosis. However, in two cases with associated injuries this perception became difficult. Regardless of the clinical diagnosis, imaging diagnosis in lesions of the locomotor system was essential, as it allowed us to assess bone involvement, accurately determine the location of the lesion, its extent and prognosis, which would not be possible only in the clinic. Through ultrasonography it was possible to classify the lesions into acute (hypoechoic areas) and chronic (hyperechoic areas or with heterogeneous pattern of variable echogenicity), in addition to the thickness and characteristic of the liquid in the tendon sheath, which are also important aspects for lesion classification. Thus, we conclude that the dorsal region at the carpal level is susceptible to trauma and can easily compromise the extensor tendons. And for the diagnosis and adequate conduct, it is necessary to determine ultrasound image regarding the different types of lesions, which is provided in the present study.

Enhanced somatosensory feedback modulates cutaneous reflexes in arm muscles during self-triggered or prolonged stimulation.

Somatosensory feedback plays important roles in regulating all animal movement. The effects of sensory feedback on spinally mediated neural excitability are widely studied using cutaneous electrical stimulation paradigms. Cutaneous reflex amplitudes are reduced when stimulation is self-triggered instead ofexternally triggered. Altered spinal excitability and motor output are also observed following sustained stimulation with various parameters. Our purpose was to probe for interactions between mode and duration by investigating muscle responses following enhanced cutaneous stimulation. Fifteen neurologically intact participants were recruited. Cutaneous reflexes in the extensor carpi radialis (ECR) were evoked with brief (15ms, 300Hz) or sustained (300ms, 50Hz) stimulation trains. Stimulation was applied to the superficial radial or median nerve at the wrist and triggered by: (1) a computer program (random-triggered); (2) muscle contraction (EMG-triggered); (3) the participant pressing a button themselves (button-triggered). During each condition, isometric contractions were performed with ECR muscle activity maintained at 10, 25, 35, and 50% of maximal voluntary contraction. Stronger inhibitory reflexes were found following brief superficial radial nerve stimulation was EMG-triggered suggesting that modulation of cutaneous reflex excitability is specific to the timing when sensory 'cues' are applied during muscle contraction. No difference was observed following sustained stimulation applied to the superficial radial nerve meaning that brief and sustained stimulation affect the cutaneous pathways differentially. Nerve-specific responses were found between superficial radial and median nerve stimulation, such that greater inhibition was induced by EMG-triggered sustained stimulation to the median nerve. These observations are critical in moving beyond pathway phenomenology toward targeted sensory enhancement and amplified motor output in rehabilitation and training.

Differential Effect of Visual and Proprioceptive Stimulation on Corticospinal Output for Reciprocal Muscles.

This study investigated the corticospinal excitability of reciprocal muscles during tasks involving sensory difference between proprioceptive and visual inputs. Participants were instructed to relax their muscles and to observe a screen during vibratory stimulation. A video screen was placed on the board covering the right hand and forearm. Participants were randomly tested in four conditions: resting, control, static, and dynamic. The resting condition involved showing a black screen, the control condition, a mosaic patterned static videoclip; the static condition, a static videoclip of wrist flexion 0°; and the dynamic condition, a videoclip that corresponded to each participant’s closely-matched illusory wrist flexion angle and speed by vibration. Vibratory stimulation (frequency 80 Hz and duration 4 s) was applied to the distal tendon of the dominant right extensor carpi radialis (ECR) using a tendon vibrator in the control, static, and dynamic conditions. Four seconds after the vibratory stimulation (end of vibration), the primary motor cortex at the midpoint between the centers of gravity of the flexor carpi radialis (FCR) and ECR muscles was stimulated by transcranial magnetic stimulation (TMS). The ECR motor evoked potential (MEP) amplitudes significantly increased in the control condition compared to the resting condition, whereas the FCR MEP amplitudes did not change between the resting and control conditions. In addition, the ECR MEP amplitudes significantly increased in the static condition compared to the dynamic condition. However, the FCR MEP amplitudes significantly increased in the dynamic condition compared to the static condition. These results imply that the difference between visuo-proprioceptive information had an effect on corticospinal excitability for the muscle. In conclusion, we found that proprioceptive and visual information differentially altered the corticospinal excitability of reciprocal muscles.

Gross anatomical adaptations of the craniolateral forearm muscles in Tamandua mexicana (Xenarthra: Myrmecophagidae): development of accessory muscles and rete mirabile for its arterial supply

The northern tamandua (Tamandua mexicana) is a xenarthran mammal with a distribution from Mexico to Peru. This species arrives to wildlife care centres due to illegal trafficking and attacks by domestic dogs, both of which are situations where the northern tamandua's thoracic limbs (forelimbs) can be affected. As such, it is necessary to have anatomical studies that allow us to perform better medical and surgical procedures. Among these, studies about the musculoskeletal system also aid in the muscular reconstructions of extinct species. The aim of this study was to characterize the craniolateral muscles of the forearm in Tamandua mexicana and compare them with other Xenarthrans to determine their gross adaptations. Six dead specimens were used, and none were sacrificed for the purpose of this investigation. In five specimens, arterial repletion was done. Four were fixed with 10% formaldehyde and 5% glycerin, and two were dissected in fresh. All were dissected in the Veterinary Anatomy Laboratory of the Universidad del Tolima. The weights of the muscles from seven forearms were taken and divided in three functional groups for comparison with non-parametric statistics. Two muscular groups were found: one superficial formed by the brachioradialis, brachioradialis accesorius, extensor carpi radialis, extensor digitorum communis, extensor digitorum lateralis and extensor carpi ulnaris; and one deep muscular group formed by the supinator, extensor digiti III et IV, abductor digiti I longus, and extensor digiti I et II. They were supplied by different branches of the cranial interosseous, transverse cubital and superficial brachial arteries, which had the shape of rete mirabile; and all muscles were innervated by the deep branch of the radial nerve. The presence of the brachioradialis accesorius muscle in this species allows its hand to remain in semi-supination when it is mobilized in a quadrupedal manner. It must also support elbow flexion together with the action of the brachioradialis and the extensor carpi radialis muscles. All the antebrachial digital muscles sent tendons for the digit III making it the most functional for different grip activities such as climbing trees and searching for its food, however, the most strength was directed to supination and carpal extension, and therefore also to the flexion of the elbow.

Modulation of reciprocal inhibition at the wrist as a neurophysiological correlate of tremor suppression: a pilot healthy subject study.

It has been shown that Ia afferents inhibit muscle activity of the ipsilateral antagonist, a mechanism known as reciprocal inhibition. Stimulation of these afferents may be explored for the therapeutic reduction of pathological tremor (Essential Tremor or due Parkinson's Disease, for example). However, only a few studies have investigated reciprocal inhibition of wrist flexor / extensor motor control. The main goal of this study was to characterize reciprocal inhibition of wrist flexors / extensors by applying surface electrical stimulation to the radial and median nerves, respectively. Firstly, the direct (M) and monosynaptic (H) reflex responses to increasing median and radial nerve stimulation were recorded to characterize the recruitment curve of the flexor carpi radialis (FCR) and extensor carpi radialis (ECR) muscles, respectively. Based on the recruitment curve data, we then stimulated the median and radial nerves below (<; MT) and above (> MT) motor threshold (MT) during a submaximal isometric task to assess the amount of inhibition on ECR and FCR antagonist muscles, respectively. The stimulation of both nerves produced a long-duration inhibition of the antagonist motoneuron pool activity. On average, maximum peak of inhibition was 27 ± 6% for ECR and 32 ± 9% for FCR with stimulation <; MT; maximum peak of inhibition was 45 ± 7% for ECR and 44 ± 13% for FCR when using stimulation > MT. These results validate this neurophysiological technique that demonstrates a mechanism similar to classical reciprocal Ia inhibition reported for other limb joints and that can be used to benchmark strategies to suppress pathological tremor.