In order to evaluate the Guizhou Weining to Weizhang (qian dian) highway engineering construction affects the surrounding environment, according to the nature of the construction project, scale, location, using production technology or pollution prevention and prevention measures for analysis, through the water environment, air environment, sound environment, ecological environment four evaluation factor analysis and evaluation. Through eight working area construction waste water, sewage water quality test analysis, ambient air and sound environment sensitive point 44, and construction along the 200m land, vegetation, wildlife, wood trees four aspects of the ecological environment evaluation, and the compensation method, scoring method and analysis method of the proposed project construction project environmental profit and loss has carried on the qualitative analysis. The analysis results show that the positive benefits of environmental economy generated by the proposed expressway are predominant, so the project is feasible from the perspective of environmental protection.