ABSTRACT The solar absorption-subcooled compression hybrid cooling system (SASCHCS), in which the cooling capacity of absorption subsystem serves as the subcooling power of compression subsystem, is energy-efficient for high-rise buildings. Because the existing design guideline of system is based on the conventional exergy theory and the advanced exergy analysis of absorption and vapor compression chillers is from the endogenous avoidable portion instead of the sum of the avoidable exergy destruction, it is incapable to design the SASCHCS exactly by such findings. As a result, the systematical advanced exergy analysis of SASCHCS is performed. The advanced exergy model of facilities is built at first. Subsequently, various exergy destructions for different conditions are analyzed. Finally, the improvement potential of components is assessed based on the sum of the avoidable exergy destruction, defined as the sum of endogenous avoidable portion of k-th component and exogenous one of remaining components led by irreversibilities of k-th component. Though the compressor concentrates the most exergy destruction of SASCHCS, 62% of its exogenous exergy destruction is caused by the irreversibilities of the condenser of the compression subsystem, making the condenser the most important component of SASCHCS. The paper is helpful to promote the design of SASCHCS.