In the emergence of transformative global economy, information system has became a necessity in businesses to obtain organizations operational excellence, adaptation to new business models, improved decision making and providing exceptional customer service, and eventual competitive advantage of the enterprise setting while keeping business alliances. This paper presents sectors of economy serviced by the pre-industry developers, explores the evolution of computer-based information system designed and developed by pre-industry system developers, and examine the effects of an information system in business to countervail indentified recurring problems. Nineteen of forty-six identified sectors of economy falls in the categories of primary, secondary, tertiary, quarternary and quinary were the recipient of computer-based system designed and developed. There have been several effects of computer-based systems to organizations, including the implied relevance to their business processes, continuum process improvement, business process reengineering, business driver and facilitator, and customer satisfaction.