Episodes Of Evolution Research Articles

A taxon-rich and genome-scale phylogeny of Opisthokonta.

Ancient divergences within Opisthokonta-a major lineage that includes organisms in the kingdoms Animalia, Fungi, and their unicellular relatives-remain contentious. To assess progress toward a genome-scale Opisthokonta phylogeny, we conducted the most taxon rich phylogenomic analysis using sets of genes inferred with different orthology inference methods and established the geological timeline of Opisthokonta diversification. We also conducted sensitivity analysis by subsampling genes or taxa from the full data matrix based on filtering criteria previously shown to improve phylogenomic inference. We found that approximately 85% of internal branches were congruent across data matrices and the approaches used. Notably, the use of different orthology inference methods was a substantial contributor to the observed incongruence: analyses using the same set of orthologs showed high congruence of 97% to 98%, whereas different sets of orthologs resulted in somewhat lower congruence (87% to 91%). Examination of unicellular Holozoa relationships suggests that the instability observed across varying gene sets may stem from weak phylogenetic signals. Our results provide a comprehensive Opisthokonta phylogenomic framework that will be useful for illuminating ancient evolutionary episodes concerning the origin and diversification of the 2 major eukaryotic kingdoms and emphasize the importance of investigating effects of orthology inference on phylogenetic analyses to resolve ancient divergences.

Permo-Triassic source-to-sink systems of the Turpan basin: insights into three tectonic evolutionary episodes and their implications for the formation rhythm of the Central Asian Orogenic Belt

ABSTRACT The Tianshan Orogenic Belt underwent a series of complex tectonic changes from the Late Palaeozoic to the Cenozoic, providing key insights into the evolution of the Central Asian Orogenic Belt (CAOB). The continuous Permo-Triassic sedimentary records of the Turpan Basin are among the best archives of the tectonic evolution of the Tianshan Orogenic Belt. However, the evolution of the Turpan Basin during this period is poorly understood. Using detrital zircon U-Pb chronology and geochemistry, we reconstructed the source-to-sink system changes and the basinal tectonic evolution in the Permo-Triassic, thus providing new evidence of its tectonic evolution. Our results show that the Early-Middle Permian source-to-sink systems of the Turpan Basin were mainly proximal and constrained by horst and graben landforms due to internal extension formed in the back-arc setting during accretionary orogenesis in Central Asia. In the Late Permian-Early Triassic, exotic sources, including the North Tianshan and Yili Block-Central Tianshan, dominated the source-to-sink system, which suggests that rifts were infilled and expanded across the entire thermal sag basin. In the Middle-Late Triassic, the sediment sources diversified, with external and internal provenances revealing that a foreland basin formed with thrusting at the southern margin, and the intraplate-associated Bogda forebulge experienced initial uplift, signifying that the CAOB gradually changed from an accretionary to an extrusive orogeny. The three evolutionary episodes of the Turpan Basin implicated the long-lasting effect of the orogenic process from the final closure of Palaeo-Asian Ocean to the following build-up of the CAOB.

Silurian ocean island basalt magmatism and Devonian−Carboniferous polymetamorphism: 100 million years in the Western Blue Ridge, USA

The tectonic configuration and evolution of southern Appalachian orogenic episodes are constrained, to a large extent, by knowledge of the timing and environment of pre- or syn-orogenic sediment deposition along with their subsequent thermal and deformational histories. The orogenic events that gave rise to regional folding and Barrovian metamorphism of the Western Blue Ridge (WBR) terrane are a classic example. We present new U-Pb and 40Ar-39Ar results bearing on the timing of magmatism and subsequent metamorphism of the Marble Hill Hornblende Schist (MHHS) of the WBR (southeastern USA). The schist is a key marker unit in the Murphy synclinorium, a central structure in the tectonic configuration of the WBR. The MMHS originated as basaltic volcanics overlying the Murphy Marble at the base of the Mineral Bluff Group. Ocean island basalt geochemistry and a zircon U-Pb age of ca. 437 Ma for the MHHS is consistent with plume-related volcanism in a Silurian remnant ocean basin of the Iapetus Ocean. Hornblende 40Ar-39Ar and rutile U-Pb ages for the MHHS are ca. 380−340 Ma and ca. 320 Ma, respectively, and record subsequent amphibolite facies metamorphism during Devonian Acadian orogeny and the deformation through regional folding and thrusting during the Carboniferous Alleghanian orogeny. The new age constraints for the MHHS require that “isograds” mapped in the region of the Murphy Belt are actually polymetamorphic mineral distributions that developed at least in part through post-Silurian tectonic events.

Long-range transport impact of a severe dust storm over the Yangtze River Basin region and its modeling sensitivity to dust emission scheme

Dust storms frequently occur in the spring over East Asia, affecting southern Mongolia and northeast China. An exceptionally powerful dust storm occurred in East Asia from March 14th to March 18th, 2021. To investigate the ability of climate models to simulate severe dust storms, we employed the Weather Research Forecast model coupled with chemistry (WRF-Chem) with Goddard Chemistry Aerosol Radiation and Transport (GOCART), SHAO and KOK dust emission schemes to simulate the evolution of this event and to characterize dust aerosols long-range transport. Results showed that this storm was caused by a Mongolian cyclone depicted at 850 hPa with a cold front, which swept dust aerosols southeastward across southern Mongolia to northeast China. Model evaluation with satellite-retrieved Aerosol Optical Depth (AOD) and observational PM10 concentrations revealed that the SHAO dust emission scheme performed better in simulating spatial and temporal distribution of AOD over the Gobi Desert (GD) but overestimated them over Taklimakan Desert (TD). In contrast, the GOCART dust emission scheme underestimated AOD over most areas except the Taklimakan Desert; the KOK dust emission scheme overestimated them over both TD and GD. Overall, the SHAO dust emission scheme had good performance in simulating the surface PM10 concentrations over the Yangtze River Basin (YRB) and depicted an increase in PM10 concentrations, which denoted the transport of dust aerosols over YRB. As a better description of the physical process of dust emission flux over the eastern region of the Gobi Desert, the SHAO dust emission scheme depicted well the spatial and temporal evolution of dust plume episodes, especially over northeast China and YRB. The significant differences in dust emission fluxes between the three dust emission schemes were attributed to the sensitivity of threshold friction velocity and erodibility factor. Thereunto, the SHAO dust emission scheme incorporated well soil particle size distribution and threshold velocity to produce the dust emission flux, which allowed higher dust emission flux over the eastern GD and under strong southwesterly transported dust aerosols to East Central China's region of North China Plain (NCP) and YRB. This study will help further the simulation of extreme dust events more accurately and the exploration of climate change's effect on dust events over East Asia.

Volcanic soil gas 4He/CO2 ratio: a useful geochemical tool for real-time eruption forecasting

At many dormant volcanoes, magmatic gases are not channeled through preferential degassing routes as fumaroles and only percolate through the flanks of the volcano in a diffuse way. This type of volcanic gas emission provides valuable information, even though the soil matrix contains an important atmospheric component. This study aimed to demonstrate that chemical ratios such as He/CO2 in soil gases provide excellent information on the evolution of volcanic unrest episodes and help forecast the volcanic eruption onset. Before and during the occurrence of the October 2011–March 2012 submarine of El Hierro, Canary Islands, more than 8500 soil He analyses and diffuse CO2 emission measurements were performed. The results show that the soil He/CO2 emission ratio began increasing drastically one month before eruption onset, reaching the maximum value 10 days before. During the eruptive period, this ratio also showed a maximum value several days before the period with the highest magma emission rate. The He/CO2 ratio was also helpful in forecasting the eruption onset. We demonstrate that this tool can be applied in real-time during volcanic emergencies. Our results also encourage a reevaluation of the global He emission from the subaerial volcanism.

Episodic evolution of intracontinental orogenic deformation: Insight from the southern Bogda fold-and-thrust belt of the Tianshan Mountains, NW China

The Mesozoic-Cenozoic Tianshan orogenic belt, a key area for studying intracontinental orogenic deformation, experienced multiple uplift episodes due to the far-field effects from a series of collision events along the southern margin of Eurasia. Focusing on the fold-and-thwrust belt at the southern margin of the Bogda Mountain, a branch of the eastern Tianshan orogenic belt, we integrated 2D seismic data, borehole and outcrop data to construct a balanced and sequentially restored cross-section across the central part of this belt. The activities and mechanical evolution of the major faults were analyzed by using the discrete-element modeling (DEM) method, offering new insights into the tectonic transformation of the Turpan-Hami Basin influenced by episodic uplifts of the Bogda Mountain in an intracontinental setting. The studied fold-and-thrust belt can be divided into two deformation systems: (i) the piedmont deformation system, comprising a southward basement thrust system and a thin-skinned thrust system on Jurassic detachment, and (ii) the thrust front belt, exhibiting an en-echelon pattern in the basin center and featured by fault-propagation folds along the lower Jurassic coal unit. Stratigraphic and reported thermochronological analyses pinpoint four key contractional deformation periods: Late Jurassic, Late Cretaceous, Paleocene-Pliocene, and Pleistocene-present. The DEM numerical simulation results indicate a critical conical Coulomb wedge model governed by the episodic activities of the southern Bogda fold-and-thrust belts from the Mesozoic to the Cenozoic. Surface processes (syntectonic erosion/deposition) significantly impacted differential activities between the orogenic belt and the basin's thrust structures. We propose that periodic arid climates in the Tianshan Mountains reduced erosion rates, promoting the expansion of the southern Bogda fold-and-thrust belts toward the basin and the widening of the orogenic belt.

Diverse Structural Styles of the Northeastern Tethyan Himalaya in Southern Tibet Reveal the Early Collisional Tectonics of India and Asia

AbstractThe poor understanding of the structural history of the Late Triassic flysch in the northeastern Tethyan Himalaya has caused many disputes regarding India‐Asia collisional tectonics. Here, we conducted an integrated study including tectonostratigraphic analysis, structural analysis, and zircon U‒Pb and muscovite 40Ar/39Ar dating to unravel the structural evolution of the Late Triassic flysch. Field geological mapping revealed that the flysch can be subdivided into three structural units, including the Gyaca mélange, Qiongjie‐Dengmu shear zone and Langjiexue fold‐thrust belt. The three units all contain voluminous siliciclastic rocks deposited in an abyssal submarine fan environment at the Indian passive continental margin. The Gyaca mélange shows a two‐stage deformation process that generated a collisional mélange resulting from the subduction of the Indian passive continental margin. 40Ar/39Ar dating of top‐to‐the‐south shear bands and block‐in‐matrix structure indicate that the India‐Asia collision happened no later than the Selandian (ca. 60 Ma). The divergent imbricated thrusting and folding of the Gyaca mélange and Langjiexue fold‐thrust belt formed a positive flower structure. The zircon U‒Pb and 40Ar/39Ar dating of syntectonic dikes and sericite flakes within the Gyaca mélange yield ages of ca. 56–55 Ma for the genesis of the divergent structures. Moreover, the Qiongjie‐Dengmu dextral shear zone yields a sericite 40Ar/39Ar age of ca. 35 Ma and thus indicates a transient strike‐slip stress regime. Generally, the early India‐Asia collision tectonics in the northeastern Tethyan Himalaya showed episodic evolution with changing structural styles from mélange formation to imbricate fold‐thrust belt development and finally strike‐slip shear generation.

From the detection of monitoring anomalies to the probabilistic forecast of the evolution of volcanic unrest: an entropy-based approach

Owing to the current lack of plausible and exhaustive physical pre-eruptive models, often volcanologists rely on the observation of monitoring anomalies to track the evolution of volcanic unrest episodes. Taking advantage from the work made in the development of Bayesian Event Trees (BET), here we formalize an entropy-based model to translate the observation of anomalies into probability of a specific volcanic event of interest. The model is quite general and it could be used as a stand-alone eruption forecasting tool or to set up conditional probabilities for methodologies like the BET and of the Bayesian Belief Network (BBN). The proposed model has some important features worth noting: (i) it is rooted in a coherent logic, which gives a physical sense to the heuristic information of volcanologists in terms of entropy; (ii) it is fully transparent and can be established in advance of a crisis, making the results reproducible and revisable, providing a transparent audit trail that reduces the overall degree of subjectivity in communication with civil authorities; (iii) it can be embedded in a unified probabilistic framework, which provides an univocal taxonomy of different kinds of uncertainty affecting the forecast and handles these uncertainties in a formal way. Finally, for the sake of example, we apply the procedure to track the evolution of the 1982–1984 phase of unrest at Campi Flegrei.

Evolution of Ozone Formation Sensitivity during a Persistent Regional Ozone Episode in Northeastern China and Its Implication for a Control Strategy.

In recent years, the magnitude and frequency of regional ozone (O3) episodes have increased in China. We combined ground-based measurements, observation-based model (OBM), and the Weather Research and Forecasting and Community Multiscale Air Quality (WRF-CMAQ) model to analyze a typical persistent O3 episode that occurred across 88 cities in northeastern China during June 19-30, 2021. The meteorological conditions, particularly the wind convergence centers, played crucial roles in the evolution of O3 pollution. Daily analysis of the O3 formation sensitivity showed that O3 formation was in the volatile organic compound (VOC)-limited or transitional regime at the onset of the pollution episode in 92% of the cities. Conversely, it tended to be or eventually became a NOx-limited regime as the episode progressed in the most polluted cities. Based on the emission-reduction scenario simulations, mitigation of the regional O3 pollution was found to be most effective through a phased control strategy, namely, reduction of a high ratio of VOCs to NOx at the onset of the pollution and lower ratio during evolution of the O3 episode. This study presents a new possibility for regional O3 pollution abatement in China based on a reasonable combination of OBM and the WRF-CMAQ model.

A Non-Linear Role of Hyperlipidemia on Progression of Intracranial Atherosclerotic Plaques and Acute Downstream Ischemic Events.

Intracranial atherosclerotic stenosis (ICAS) is the leading cause of ischemic stroke worldwide. Hyperlipidemia is a major contributor to atherosclerosis. However, the effect of hyperlipidemia on the evolution of intracranial atherosclerotic plaques and downstream ischemic episodes remains unclear. In this study, we aimed to assess the radiological features of ICAS plaques and to explore the relationship between hyperlipidemia and plaque progression. We included people with ICAS (≥50% stenosis) undergoing high-resolution magnetic resonance imaging. The culprit plaque was defined as the sole, or in case of multiple stenosis, the narrowest plaque on the intracranial artery responsible for acute ischemic stroke. Demographic, clinical data, plaque features on MRI, and lipid parameters were compared between culprit and non-culprit plaques. Plaque enhancement was graded as Grade 0, 1 and 2 by comparing to the adjacent normal vessel wall and pituitary funnel after contrast enhancement on T1-weighted sequences. 162 patients were included (mean age 57.7±12.1 years, male 61.6%), 110 of whom were identified as culprit plaque with an ipsilateral acute stroke. High-grade enhancement was the most prominent MRI feature of the culpable plaque (Grade-2: OR 6.539, 95%CI 1.706-23.707, p=0.006). LDL cholesterol was significantly associated with overall acute ischemic stroke caused by culprit plaque. After stratification by enhancement grading LDL was independently associated with ischemic events in Grade-1 enhancement plaques (OR 6.778, 95%CI 2.122-21.649, p=0.001). In patients with Grade-2 enhancement plaques, however, LDL was not associated with ischemic event; in contrast, Neutrophil/Lymphocyte ratio was independently associated with ischemic events caused by Grade-2 enhancement plaques (OR 2.188, 95%CI 1.209-3.961, p=0.010). LDL was related with ischemia events in intermediate stage of intracranial atherosclerotic plaque progression, an excellent period for intensive lipid-lowering treatment. In advanced stage, inflammatory agents maybe the main contributor to ischemic events.

Episodic evolution of a protracted convergent margin revealed by detrital zircon geochronology in the Greater Caucasus

AbstractConvergent margins play a fundamental role in the construction and modification of Earth's lithosphere and are characterized by poorly understood episodic processes that occur during the progression from subduction to terminal collision. On the northern margin of the active Arabia‐Eurasia collision zone, the Greater Caucasus Mountains provide an opportunity to study a protracted convergent margin that spanned most of the Phanerozoic and culminated in Cenozoic continental collision. However, the main episodes of lithosphere formation and deformation along this margin remain enigmatic. Here, we use detrital zircon U–Pb geochronology from Paleozoic and Mesozoic (meta)sedimentary rocks in the Greater Caucasus, along with select zircon U–Pb and Hf isotopic data from coeval igneous rocks, to link key magmatic and depositional episodes along the Caucasus convergent margin. Devonian to Early Carboniferous rocks were deposited prior to Late Carboniferous accretion of the Greater Caucasus crystalline core onto the Laurussian margin. Permian to Triassic rocks document a period of northward subduction and forearc deposition south of a continental margin volcanic arc in the Northern Caucasus and Scythian Platform. Jurassic rocks record the opening of the Caucasus Basin as a back‐arc rift during southward migration of the arc front into the Lesser Caucasus. Cretaceous rocks have few Jurassic‐Cretaceous zircons, indicating a period of relative magmatic quiescence and minimal exhumation within this basin. Late Cenozoic closure of the Caucasus Basin juxtaposed the Lesser Caucasus arc to the south against the crystalline core of the Greater Caucasus to the north and led to the formation of a hypothesized terminal suture. We expect this suture to be within ~20 km of the southern range front of the Greater Caucasus because all analysed rocks to the north exhibit a provenance affinity with the crystalline core of the Greater Caucasus.

Detecting Episodic Evolution through Bayesian Inference of Molecular Clock Models.

Molecular evolutionary rate variation is a key aspect of the evolution of many organisms that can be modeled using molecular clock models. For example, fixed local clocks revealed the role of episodic evolution in the emergence of SARS-CoV-2 variants of concern. Like all statistical models, however, the reliability of such inferences is contingent on an assessment of statistical evidence. We present a novel Bayesian phylogenetic approach for detecting episodic evolution. It consists of computing Bayes factors, as the ratio of posterior and prior odds of evolutionary rate increases, effectively quantifying support for the effect size. We conducted an extensive simulation study to illustrate the power of this method and benchmarked it to formal model comparison of a range of molecular clock models using (log) marginal likelihood estimation, and to inference under a random local clock model. Quantifying support for the effect size has higher sensitivity than formal model testing and is straight-forward to compute, because it only needs samples from the posterior and prior distribution. However, formal model testing has the advantage of accommodating a wide range molecular clock models. We also assessed the ability of an automated approach, known as the random local clock, where branches under episodic evolution may be detected without their a priori definition. In an empirical analysis of a data set of SARS-CoV-2 genomes, we find "very strong" evidence for episodic evolution. Our results provide guidelines and practical methods for Bayesian detection of episodic evolution, as well as avenues for further research into this phenomenon.

Lower Eocene carbonate ramp clinoforms of the southern Tethys; Zagros Foreland Basin, SW Iran: Sequence stratigraphy architecture, basin physiography and carbonate factory controlling parameters

AbstractExcellent cliff exposures in the Khush‐Ab and Chenareh anticlines (Zagros Foreland Basin, SW Iran) offer a good opportunity to document stratal geometries, paleofacies heterogeneity, depositional architecture and depositional cycles of the Lower Eocene sedimentary basin system. These unique outcrops containing six logged sections have been studied across a large‐scale transect, covering ca. 10 km of continental (Kashkan Formation), carbonate‐dominated platforms (Taleh‐Zang Formation) and submarine fan to basin‐floor settings (Amiran and Pabdeh formations). Field observations of the bedding geometries revealed a set of NE–SW oriented carbonate ramp clinoforms (clinoformal units 1–4) with sigmoidal cross‐sectional shapes and an internal fore‐stepping architecture. Based on detailed facies analysis, six facies associations (FA) were identified (FA.I to FA.VI), which are interpreted to have been deposited laterally in the continental, proximal to distal and deep‐water settings of a distally steepened carbonate ramp. According to the stratal stacking pattern, bounding surface, facies architecture and internal makeup of carbonate clinoforms, four H‐F‐cycles (cycle I–IV) corresponding to a lower hierarchical rank (fourth‐order cycle) were recognized and nested within the regressive stacking pattern (HST) of a higher hierarchical rank (third‐order sequence). These H‐F‐cycles are arranged in three segments (bottomset, foreset and topset) of each clinoformal unit. Higher rank transgressive blocks (TST) discriminated each clinoformal unit by up‐deepening sets of the H‐F‐cycle V. In total, five third‐order depositional sequences were identified. The sequence, stratigraphic framework and internal makeup of this carbonate platform indicate that these carbonate sloping successions are the type of accretionary carbonate ramp clinoforms that display an ascending ramp‐slope break trajectory. Evolutionary episodes of biogenic communities, climatic change, local tectonic movements, physical processes (e.g. waves and storms) and water depth gradient are major forcing parameters that controlled the carbonate factory and depositional geometry of this Lower Eocene succession; however, carbonate‐producing organisms and eustatic sea‐level fluctuations played the first role, and local tectonic movements in response to tectonic activities of the Zagros Foreland Basin played the second role. As a result, Taleh‐Zang carbonate platforms are rich in diverse assemblages of LBFs without fragments of coral and red algae, which appear to be a consequence of a hothouse state that diminishes the global thermal gradient, weakens pycnoclines and thereby limits the turbulence.

Protocolo de manejo de pacientes con enfermedad pulmonar obstructiva crónica tras agudización en urgencias

In chronic obstructive pulmonary disease, an acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is an episode of clinical instability due to the worsening of expiratory airflow limitation or of the underlying inflammatory process. The severity of AECOPD depends on baseline risk stratification and the intensity of the acute episode. Primary Care is the epicenter of the AECOPD care circuit, but it can be extended to the out-of-hospital emergency department and the hospital itself depending on the clinical situation, the level of severity, the availability of complementary tests, and the therapeutic resources required for each patient. Recording clinical data, history, triggering factors, treatment, and evolution of previous episodes of AECOPD in the electronic medical record is an essential aspect to adjust current treatment and prevent the occurrence of future episodes.

Genesis of Pyroxenite Veins in the Zedang Ophiolite, Southern Tibetan Plateau

AbstractUnderstanding the nature of parental melts for pyroxenite veins in supra‐subduction zone (SSZ) ophiolites provides vibrant constraints on melt infiltration processes operating in subduction zones. The Zedang ophiolitic massif in the eastern Yarlung–Zangbo suture zone in Tibet consists of mantle peridotites and a crustal section of gabbro, diabase, and basalt. Veins of two pyroxenite varieties cut the southern part of the Zedang massif. These pyroxenite rocks have different geochemical characteristics, where the first variety (type‐I) has relatively higher contents of SiO2 (51.82–53.08 wt%), MgO (20.08–23.23 wt%), and ΣPGE (3.42–13.97 ppb), and lower Al2O3 (1.59–2.28 wt%) and ΣREE (1.63–2.94 ppm). The second pyroxenite variety (type‐II) is characterized by SiO2 (45.44–49.61 wt%), MgO (16.68–19.78 wt%), Al2O3 (4.24–8.77 wt%), ΣPGE (14.46–322.06 ppb), and ΣREE (5.82–7.44 ppm). Pyroxenite type‐I shows N‐MORB‐like chondrite‐normalized REE patterns. Zircon U‐Pb ages of pyroxenite type‐I (194 ± 10 Ma), associated ophiolitic gabbro (135.3 ± 2.0 Ma), and plagiogranite (124.2 ± 2.3 Ma) evidently imply episodic evolution of the Zedang ophiolites. The mineralogical and geochemical characteristics of the investigated pyroxenites can be explained by subduction‐initiated hydrous melting of metasomatized sub‐arc mantle, later overprinted by sub‐slab mantle melting triggered by upwelling asthenosphere during the Jurassic–Early Cretaceous times. The geochemical variations in pyroxenite vein composition, coupled with age differences amongst the other ophiolite units, may correspond to intermittent emplacement of pyroxenite dikes and isotropic gabbroic intrusions where the geodynamic setting progressed from arc maturation and slab rollback to slab tearing and delamination.

The Capabilities of FY-3D/MERSI-II Sensor to Detect and Quantify Thermal Volcanic Activity: The 2020–2023 Mount Etna Case Study

Satellite data provide crucial information to better understand volcanic processes and mitigate associated risks. In recent years, exploiting the growing number of spaceborne polar platforms, several automated volcanic monitoring systems have been developed. These, however, rely on good geometrical and meteorological conditions, as well as on the occurrence of thermally detectable activity at the time of acquisition. A multiplatform approach can thus increase the number of volcanological-suitable scenes, minimise the temporal gap between acquisitions, and provide crucial information on the onset, evolution, and conclusion of both transient and long-lasting volcanic episodes. In this work, we assessed the capabilities of the MEdium Resolution Spectral Imager-II (MERSI-II) sensor aboard the Fengyun-3D (FY-3D) platform to detect and quantify heat flux sourced from volcanic activity. Using the Middle Infrared Observation of Volcanic Activity (MIROVA) algorithm, we processed 3117 MERSI-II scenes of Mount Etna acquired between January 2020 and February 2023. We then compared the Volcanic Radiative Power (VRP, in Watt) timeseries against those obtained by MODIS and VIIRS sensors. The remarkable agreement between the timeseries, both in trends and magnitudes, was corroborated by correlation coefficients (ρ) between 0.93 and 0.95 and coefficients of determination (R2) ranging from 0.79 to 0.84. Integrating the datasets of the three sensors, we examined the effusive eruption of Mount Etna started on 27 November 2022, and estimated a total volume of erupted lava of 8.15 ± 2.44 × 106 m3 with a Mean Output Rate (MOR) of 1.35 ± 0.40 m3 s−1. The reduced temporal gaps between acquisitions revealed that rapid variations in cloud coverage as well as geometrically unfavourable conditions play a major role in thermal volcano monitoring. Evaluating the capabilities of MERSI-II, we also highlight how a multiplatform approach is essential to enhance the efficiency of satellite-based systems for volcanic surveillance.

Monitoring storm evolution using a high-density seismic network

Data acquired by a dense seismic network deployed in the Cerdanya basin (Eastern Pyrenees) is used to track the temporal and spatial evolution of meteorological events such as rainfall episodes or thunderstorms. Comparing seismic and meteorological data, we show that for frequencies above 40 Hz, the dominant source of seismic noise is rainfall and hence the amplitude of the seismic data can be used as a proxy of rainfall. The interstation distance of 1.5 km provides an unprecedented spatial resolution of the evolution of rainfall episodes along the basin. Two specific episodes, one dominated by stratiform rain and the second one dominated by convective rain, are analyzed in detail, using high resolution disdrometer data from a meteorological site near one of the seismic instruments. Seismic amplitude variations follow a similar evolution to radar reflectivity values, but in some stratiform precipitation cases, it differs from the radar-derived precipitation estimates in this region of abrupt topography, where radar may suffer antenna beam blockage. Hence, we demonstrate the added value of seismic data to complement other sources of information such as rain-gauge or weather radar observations to describe the evolution of ground-level rainfall fields at high spatial and temporal resolution. The seismic power and the rainfall intensity have an exponential relationship and the periods with larger seismic power are coincident. The time intervals with rain drops diameters exceeding 3.5 mm do not result in increased seismic amplitudes, suggesting that there is a threshold value from which seismic data are no longer proportional to the size of the drops. Thunderstorms can be identified by the recording of the sonic waves generated by thunders, with. Single thunders detected to distances of a few tens of kilometers. As the propagation of these acoustic waves is expected to be strongly affected by parameters as air humidity, temperature variations or wind, the seismic data could provide an excellent tool to investigate atmospheric properties variations during thunderstorms.

Recurrent Penicillin-Resistant Tonsillitis Due to Lactococcus garvieae, a New Zoonosis from Aquaculture

Zoonotic diseases are a group of infectious diseases that are transmitted naturally from animals to humans. L. garvieae is a Gram-positive bacterium which is present in the aquaculture of freshwater and marine fish. Some isolated cases of infection have been described, considering it an opportunistic agent in immunosuppressed patients. The most recent appearance of severe infections in immunocompetent patients or colonizing cardiac prostheses has set off the alarms. This manuscript presents the first two patients with recurrent tonsillitis due to L. garvieae. A 15-year-old male and an 8-year-old male had recurrent tonsillitis with more than three episodes per year. A culture of tonsillar exudate in both cases showed growth of L. garvieae with an antibiogram showing multi-resistance to antibiotics. Given the parents’ wish not to carry out surgery, an autovaccine regimen with lysed bacteria was proposed with good evolution and remission of tonsillitis episodes in both cases. The oral autovaccine produces an immunomodulatory effect and could be a therapeutic weapon in the prevention of this zoonosis. Further studies are needed to determine the importance of foodborne transmission in human L. garvieae infections and to find suitable treatments for this wide range of infections.

The interplays among meteorology, source, and chemistry in high particulate matter pollution episodes in urban Shanghai, China

High particulate matter (PM) pollution episodes still occur occasionally in urban China, despite of improvements in recent years. Investigating the influencing factors of high-PM episodes is beneficial in the formulation of effective control measures. We herein present the effects of weather condition, emission source, and chemical conversion on the occurrence of high-PM episodes in urban Shanghai using multiple online measurements. Three high-PM episodes, i.e., locally-accumulated, regionally-transported, and dust-affected ones, as well as a clean period were selected. Stagnant air with temperature inversion was found in both locally-accumulated and regionally-transported high-PM episodes, but differences in PM evolution were observed. In the more complicated dust-affected episode, the weather condition interacted with the emission/transport sources and chemical conversion, resulting in consecutive stages with different PM characteristics. Specifically, there were (1) stronger local accumulation in the pre-dust period, (2) dust-laden air with aged organic aerosol (OA) upon dust arrival, (3) pollutants being swept into the ocean, and (4) back to the city with aged OA. Our results suggest that (a) local emissions could be rapidly oxidized in some episodes but not all, (b) aged OA from long-range transport (aged in space) had a similar degree of oxygenation compared to the prolonged local oxidation (aged in time), and (c) OA aged over land and over the ocean were similar in chemical characteristics. The findings help better understand the causes and evolution of high-PM episodes, which are manifested by the interplays among meteorology, source, and chemistry, providing a scientific basis for control measures.

Recent advances in "sickle and niche" research - Tribute to Dr. Paul S Frenette.

SummaryIn this retrospective, we review the two research topics that formed the basis of the outstanding career of Dr. Paul S. Frenette. In the first part, we focus on sickle cell disease (SCD). The defining feature of SCD is polymerization of the deoxygenated mutant hemoglobin, which leads to a vicious cycle of hemolysis and vaso-occlusion. We survey important discoveries in SCD pathophysiology that have led to recent advances in treatment of SCD. The second part focuses on the hematopoietic stem cell (HSC) niche, the complex microenvironment within the bone marrow that controls HSC function and homeostasis. We detail the cells that constitute this niche, and the factors that these cells use to exert control over hematopoiesis. Here, we trace the scientific paths of Dr. Frenette, highlight key aspects of his research, and identify his most important scientific contributions in both fields.