Reconciling higher ecological water demands and economic purposes with finite freshwater resources remains one of the great management dilemmas. Low water efficiency and large water consumption in agricultural irrigation hinder the protection of river ecological flow in the water shortage areas of Northwest China. By analyzing the surplus and shortage of river ecological protection targets, the intensity guarantee rate index is innovatively proposed to quantitatively evaluate the important contribution of improved water-saving measures for river flow restoration. It compensates for the shortcomings of the duration guarantee rate index in evaluation that may mask ecological problems. Considering ecological baseflow, fish species, and landscape water demand, the ecological flow interval (6.00–12.42 m3/s) was determined. Three scenarios are highlighted for different typical years and irrigation regimes in combination with planting structure adjustment and irrigation water utilization coefficient. In 75 %, 90 %, and 95 % typical years, the maximum total annual water-savings (Scenario 3) are 57.3, 57.1, and 87.2 million m3 (sufficient irrigation); 32.2, 33.9, and 35.5 million m3 (deficit irrigation) respectively. The guarantee degree of river ecological flow under both irrigation regimes increased from the previous 65.6 % to a maximum of 91.7 % and 81.2 %. The increase in the daily guarantee rate and decrease in the intensity guarantee rate under the aforementioned three scenarios indicate a reduction of damage depth and duration of ecological flow. By using a quantitative study, it is pointed out that improving agricultural water-saving is a reasonable and necessary way to protect the river flow.