This paper is concerned with the communication protocol-based zonotopic state and fault estimation issue for a class of discrete time-varying industrial cyber-physical systems under bounded disturbances and constrained communication resources. First, in order to alleviate resource consumption, a round-robin protocol is developed to schedule the data transmission between the local sensor and the remote estimator. Second, a zonotopic set-membership estimation algorithm is developed to guarantee that the unavailable system state and fault signals could be simultaneously estimated and enclosed in a zonotope at every instant of time. Subsequently, the size of such a zonotope is minimized at each iteration by appropriately selecting a correlation matrix. Furthermore, the rigorous stability and performance analysis for the developed zonotopic estimation algorithm is provided. Finally, two simulation examples are provided to verify the obtained theoretical results.