Established Patterns Research Articles

Bioconversion protein and energy in feed into meat productivity of the young sheep

Satisfying the physiological need of body for nutrients in strict accordance with medical standards is an important task to improve the structure of nutrition and its energy value. The level of providing a person with protein animal origin is only 65% established norm. Therefore, the problem of increasing volume its production is considered relevant for nutriciology. In this regard, breeders pay special attention to identifying animal genotypes that meet these requirements, and for this it is necessary to conduct a comprehensive assessment quality of the meat productivity, taking into account transformation main nutrients feed into edible parts of the body.
 Evaluation of the efficiency animal transformation feed nutrients into body tissues is based on the use of exchange energy feed, and stored energy in form protein and fat. The study of their bioconversion into meat products makes it possible to develop rational technologies for directed rearing, pasture feeding and intensive fattening young sheep.
 This article presents results of the analysis accumulation nutrients in body and energy bioconversion with protein into the meat products of young sheep Akzhaik breed in conditions sharply continental climate of the Western region Kazakhstan. The established pattern of changes protein content in body experimental individuals is due to a decrease in the intensity of its synthesis and activation process fat deposition. According to our information, with the age of young animals, the coefficient bioconversion of feed energy into energy edible parts carcass increased to 28%, while protein, on contrary, decreased to 89%.

CMR reclassifies patients with suspected myocardial infarction with non-obstructive coronary arteries (MINOCA)

Abstract Funding Acknowledgements Type of funding sources: None. Objectives This study sought to assess the role of cardiac magnetic resonance (CMR) in investigating patients presenting with suspected acute coronary syndrome (ACS) and non-obstructed coronary arteries. Methods Consecutive patients presenting to a tertiary cardiology centre with suspected ACS and non-obstructed coronary arteries and referred for CMR were retrospectively identified. A comprehensive imaging protocol was performed to include cines, T2-weighted, and late gadolinium enhancement (LGE) sequences. Final CMR diagnosis was based on established patterns of tissue characterisation from myocardial oedema and LGE imaging, with patients grouped into five: myocardial infarction, myocarditis, Takotsubo syndrome, cardiomyopathy, and a normal CMR. Results A total of 888 patients were identified. The mean age across the cohort was 57 years (SD ±15.9 years) with 51% female patients. Median time to CMR from acute presentation was 21 days (Figure 1). Aetiology of presentation was uncertain in more than half of patients referred for CMR (483, 54.1%). Of patients with an initial uncertain aetiology, CMR was able to identify an underlying diagnosis in 74.9%. Diagnosis across the whole cohort was reclassified in 691 patients (77.8%), with overall diagnostic yield (CMR identified underlying aetiology for presentation) of 75.6%. (Figure 2). Conclusions In a large single-centre cohort of patients presenting with suspected ACS and non-obstructed coronary arteries, diagnostic yield with CMR was high at 76%. CMR reclassified nearly 80% of patients. Our results highlight the importance of CMR in the diagnostic pathway of suspected ACS and potential implications on clinical management.

In silico analysis of the solute carrier (SLC) family in cancer indicates a link among DNA methylation, metabolic adaptation, drug response, and immune reactivity.

Introduction: The oncogenic transformation is driven by genetic and epigenetic alterations influencing cancer cell fate. These alterations also result in metabolic reprogramming by modulating the expression of membrane Solute Carrier (SLC) transporters involved in biomolecules trafficking. SLCs act as tumor suppressors or promoters influencing cancer methylome, tumor growth, immune-escape, and chemoresistance. Methods: This in silico study aimed to identify the deregulated SLCs in various tumor types compared to normal tissues by analyzing the TCGA Target GTEx dataset. Furthermore, the relationship between SLCs expression and the most relevant tumor features was tackled along with their genetic regulation mediated by DNA methylation. Results: We identified 62 differentially expressed SLCs, including the downregulated SLC25A27 and SLC17A7, as well as the upregulated SLC27A2 and SLC12A8. Notably, SLC4A4 and SLC7A11 expression was associated with favorable and unfavorable outcome, respectively. Moreover, SLC6A14, SLC34A2, and SLC1A2 were linked to tumor immune responsiveness. Interestingly, SLC24A5 and SLC45A2 positively correlated with anti-MEK and anti-RAF sensitivity. The expression of relevant SLCs was correlated with hypo- and hyper-methylation of promoter and body region, showing an established DNA methylation pattern. Noteworthy, the positive association of cg06690548 (SLC7A11) methylation with cancer outcome suggests the independent predictive role of DNA methylation at a single nucleotide resolution. Discussion: Although our in silico overview revealed a wide heterogeneity depending on different SLCs functions and tumor types, we identified key SLCs and pointed out the role of DNA methylation as regulatory mechanism of their expression. Overall, these findings deserve further studies to identify novel cancer biomarkers and promising therapeutic targets.

Dendroecological Potential of Appalachian Riverscour Woodland Trees

Appalachian riverscour woodlands are intermittently flooded areas along high-energy rivers characterized by exposed bedrock and poorly developed sandy soils, high plant diversity, and scattered and stunted trees. These sites can be negatively impacted by dam construction and alterations to river hydrology, trampling associated with riverside recreation activities, and non-native species. In West Virginia, little is known about the development of riverscour woodlands or the growth and hydroclimate sensitivity of associated tree species. In this exploratory study, our objectives were to evaluate our ability to crossdate riverscour woodland trees (i.e., assign accurate calendar years to annual growth rings) as well as determine stand structure and tree establishment patterns at one site along the New River in Fayette County, West Virginia. In addition, for two species, Ulmus americana and Diospyros virginiana, we examined annual growth trends and relationships between tree growth and monthly hydroclimate, including streamflow, precipitation, and Palmer Drought Severity Index (PDSI). Seventy-three percent of all ring-width measurement series were crossdated, but results were mixed across species. Most trees were less than 50 years old and no trees established before the late 1940s. Both U. americana and D. virginiana were highly sensitive to April–August hydroclimate, but differed in response to previous year moisture availability. These findings provide new direction for the use of riverscour woodland trees in future dendroecological studies.

All inside our heads? A critical discursive review of unconscious bias training in the sciences

AbstractIn response to persistent systemic gendered and racial exclusions in the sciences, unconscious or implicit bias training is now widely established as an organizational intervention in Higher Education (HE). Recent systematic reviews have considered the efficacy of unconscious bias training (UBT) but not the wider characteristics and effects of the interventions themselves. Guided by feminist scholarship in critical psychology and post‐structuralist discourse theory, this article critically examines UBT across STEMM and in HE institutions with a discursive analysis of published studies. Drawn from systematic searches in 4 databases, we identify three types of UBT reported in 22 studies with considerable variation in intervention types, target groups, and evaluation methods. Guided by limited cognitive problematizations of unconscious bias as a problem located inside individual minds, interventions follow established patterns in neoliberal governmentality and make available specific feeling rules and subject positions. These current Equality, Diversity & Inclusion practices present a new technology of power through which organizations may regulate affect and behavior but leave structural inequalities and barriers to inclusion intact.

Blue Berets, Burning Brushfires

Abstract This article makes three important arguments. The first is that one of the most crucial factors in explaining the various outcomes of UN peacekeeping cases over the past seventy-five years can be found in the role of contingencies: the idiosyncratic circumstances that have combined to enable success or failure. The second is that these peacekeeping missions critically demonstrate the importance of focusing attention on the significant role of key domestic, regional, and external actors. The third is that contingencies at these three important levels, rather than any established security patterns or theories, are often the most critical factors in explaining the outcomes of UN peacekeeping missions over the past seven and a half decades. The choices of national and regional actors as well as external great powers often shape how these missions start, develop, and end. Examining interests and motivations in detail thus helps explain how and why UN peacekeeping missions have succeeded or failed.

Beyond mere facts: Epistemic profiles of conclusions to English- and Polish-language linguistics articles

Expressions of epistemic stance in academic discourse reflect not only the authors’ commitment to the truth of what is being said, but also their awareness of other members of the discourse community, the current thinking within the discipline, and the established patterns of interaction. Stance-taking is strongly embedded in culture and language, as demonstrated in numerous studies that focus on L2 academic English (e.g. Hinkel 2002; Dontcheva-Navratilova 2018; Wu and Paltridge 2021) and, less often, academic communication in various linguistic contexts (e.g. Perez-Llantada 2010). This paper purues this latter line of inquiry and proposes a contrastive analysis of epistemic markers in conclusions to English- and Polish-language linguistics articles in an attempt to identify their epistemic profiles. Epistemic profile refers here to a combination of two features: the epistemic modal value (Halliday 1985/1994) which is marked more frequently than others across a text or text fragment, and the concurrence of modality markers with specific rhetorical moves (Swales 1990; Yang and Allison 2003). Thus, it provides information about the value of modalization and the type of content that tends to be modalized. The analysis was based on a two-part corpus of conclusions to 400 linguistics articles, with 200 English-language articles drawn from international databases and 200 Polish-language articles published in recognized national journals. In the first stage, the frequencies of epistemic markers in the two sub-corpora were calculated (Scott 2008) and a statistical analysis was applied to determine whether the differences were significant. In the second stage, 50 concluding sections from each sub-corpus were manually annotated for rhetorical moves to determine whether epistemic markers tended to occur within specific moves. The findings show statistically significant differences in the frequencies of high- and low-value epistemic markers in the sub-corpora and a tendency for epistemic markers to occur within moves that offer interpretive content.

Diet and Asthma: A Narrative Review

Asthma is a chronic respiratory disease that impacts millions of people worldwide. Recent studies suggest that diet may play a role in asthma pathophysiology. Several dietary factors have been recognized as potential contributors to the development and severity of asthma for its inflammatory and oxidative effects. Some food groups such as fruits and vegetables, whole grains, and healthy fats appear to exert positive effects on asthma disease. On the other hand, a high consumption of dietary salt, saturated fats, and trans-fat seems to have the opposite effect. Nonetheless, as foods are not consumed separately, more research is warranted on the topic of dietary patterns. The mechanisms underlying these associations are not yet fully understood, but it is thought that diet can modulate both the immune system and inflammation, two key factors in asthma development and exacerbation. The purpose of this review is to examine how common food groups and dietary patterns are associated with asthma. In general, this research demonstrated that fruits and vegetables, fiber, healthy fats, and dietary patterns considered of high quality appear to be beneficial to asthma disease. Nonetheless, additional research is needed to better understand the interrelation between diet and asthma, and to determine the most effective dietary interventions for asthma prevention and management. Currently, there is no established dietary pattern for asthma management and prevention, and the nuances of certain food groups in relation to this disease require further investigation.

Substantiation of Drilling Parameters for Undermined Drainage Boreholes for Increasing Methane Production from Unconventional Coal-Gas Collectors

Decarbonization of the mining industry on the basis of closing the energy generation, on the basis of cogeneration of coal mine methane, and on the internal consumption of the mine is a promising direction in ensuring sustainable development. Known problems of deep underground mining do not allow for realizing the potential of man-made gas reservoirs due to the deterioration of the conditions of development of reserves of georesources. The aim of the work was to improve recommendations for the substantiation of drilling parameters for undermined drainage boreholes for increasing methane production from unconventional coal-gas collectors. The authors’ approach innovation lies in the possibility of using the established patterns of better natural stability of undermined boreholes to optimize them as spatial orientation parameters in an existing drilling passport for the improvement of methane extraction productivity. For this purpose, smoothing (LOESS) of the experimental data of two similar types of wells was used; then deterministic interpolation methods in combination with a three-dimensional representation of the response function in “gnuplot” were used. As a result, it was found that the increase in the inclination angle from 40° to 60° leads to a significant transformation of the model of the studied process, accompanied by a decline in the dynamics of methane emission and a decrease in the distance of the productive work zone of this type of well from 13 to 5 m before the roof landing, which then is replaced by a sharp increase in the productive work zone up to 35 m ahead of the longwall face. This allows under specific conditions for recommending increasing the productivity of methane capex from technogenic disturbed coal-gas reservoir replacement of wells with a smaller angle of rise to the transition to a more frequent grid of clusters from wells #4.

Future horizons in the analysis of technical-tactical performance in women's football: a mixed methods approach to the analysis of in-depth interviews with professional coaches and players.

Scientific knowledge about the criteria that determine success in women's football is beginning to develop. This study was carried out with the aim of detecting regularities in the offensive success in elite women's football, as well as carrying out an interrelational analysis of linked behaviors, based on in-depth interviews with professional coaches and players. Eight in-depth interviews were conducted with professional Spanish coaches and players. The interviews were analyzed by indirect observation from a process of "quantitizing," through the construction of an indirect observation ad hoc instrument. The segmentation of the transcription of the interviews was carried out in textual units, and the creation of a matrix of codes. Two types of analysis were performed: first, a lag sequential analysis (LSA) was performed and, then, a polar coordinates analysis (PCA), which allowed to find, respectively, a wide number of established communicative patterns with offensive performance in women's football, as well as an interrelational map between the established codes. The results obtained allowed us to suggest a statistically significant association between success in women's football and criteria such as the physical characteristics of a particular player, the individual action space, the duration of the attack, the type of dynamic start, individual and collective technical and tactical aspects, decision making and the type of attack used. Based on these results, the influence of these criteria on performance in women's soccer can be studied in future studies. In addition, with the aim of increasing the validity of these conclusions, new studies on this subject may be carried out following strategies such as the Delphi Method.

Detecting Data Outliers with Machine Learning

Anomalies are instances or collections of data that occur very rarely in a dataset and where features differ significantly from most of the data. In the age of technology, data is widely used in all sectors. Thus, anomalies in the data may produce problems if they are not detected. Anomaly detection involves examining specific data points and detecting rare occurrences that seem suspicious because they are different from the established pattern of behaviors. In this study, an approach to anomaly detection is built using a machine learning technique. The clustering distance-based method (k_means) is adopted. First, the anomaly existence is tested using p_value. After that, the anomaly data is detected using the clustering method. The proposed method was tested using real data collected from Kaggle. The results show the good performance of the k_means algorithm in the detection of outlier data.

Exploring the Impact of Negative Words Used in Online Feedback in Hotel Industry: A Sentiment Analysis, N-gram, and Text Network Analysis Approach

This study examines the words and situations that trigger and those that do not trigger a hotel response when customers post negative online feedback. The research explores, through sentiment analysis, bigrams, trigrams, and word networking, the valence of online reviews of five important hotels in Las Vegas. Only the feedback that has been categorized as negative by the algorithm is selected. In correspondence to this feedback, the existence of answers from the hotels is checked together with the response style. While the negative valence of the feedback can represent a mixture of subjective and objective emotions, there are common features present in their expression. On the responses side from the hotel, not all the reviews receive attention. As such, the negative feedback words are extracted and separated into those that belong to reviews that obtain a response and those that do not. The replies are standardised by following an established pattern. This paper aims to contribute to a prominent issue in tourism that is little tackled: responses to feedback. The findings may help the hotels’ management explore different paths to improve their services and responses alike. Behavioural marketing researchers might want to use these results to confirm the existence of such patterns in different datasets or situations.

International trade under new stresses in the development of the global economy

In the past few years, the international exchange of goods and services has faced two unprecedented shocks – a pandemic and increased geopolitical tensions. These shocks significantly weaken international trade, slow down the development of global supply chains and cause serious damage to the global economy as a whole. This article considers the problems of sustainability of international trade in goods and services in the light of the analysis of new triggers for its development, as well as taking into account the changed context for exporting and importing countries. The author came to the conclusion that the established patterns of participation of countries in international trade will undergo significant changes. The main directions for increasing the stability of global supply chains, as well as Russia's participation in it in the face of severe sanctions pressure, are identified. The prospects for the development of international trade are assessed by us as gloomy and uncertain, and exchange risks are elevated. A number of areas of international trade policy that could be effective for adjusting current trade relations between countries were discussed.

Mpox vaccination in global perspective: priorities and challenges.

After the global panic created by COVID-19, the monkeypox (Mpox) virus emerged as a new challenge for the world population. As of 19 January 2023, a total of 84,733 cases across 110 countries/territories including 80 deaths has been reported. The virus has been transmitted to nonendemic countries in a short span of 6 months warranting WHO to declare Mpox, a Public Health Emergency of International Concern on 23 July 2022. As the Mpox virus is crossing geographical boundaries without established transmission patterns, there is an urgent need for new scientific strategies from global researchers to contain it before turning into the next pandemic. The control of Mpox outbreaks primarily relies on various public health measures such as proper surveillance, contact tracing, rapid diagnosis, isolation and care of patients, and vaccination. At present, there are three vaccines viz. ACAM2000, MVABN, and LC16 are in consideration and have been approved in several jurisdictions for ongoing Mpox outbreak. Prioritization of individuals along with the production of specific Mpox vaccine is need of the hour to meet out the global demand of Mpox vaccination.

Jolted: How task-based jolts disrupt status conferral by impacting higher and lower status individuals' generosity.

Despite growing evidence that the status conferred to individuals in organizations can change, few theoretical accounts explain when and how established patterns of status conferral are disrupted. We develop a theory of "task-based jolts"-organizational-level events that alter group tasks and goals in a way that requires employees to adjust the way they work-as a significant catalyst to disrupt status conferral in an existing hierarchy. We employed a multimethod design across two empirical studies (Study 1-quasifield experiment; Study 2-yoked experiment) and found that jolts are appraised differently by higher and lower status individuals, and as such, the jolt has contrasting implications for their generosity toward their coworkers and ultimately the status conferred to them. When employees' initial status is higher, they appraise a task-based jolt as self-threatening, undermining their concern for others and their generosity, which ultimately causes them to lose status in the immediate aftermath of the jolt. Conversely, when employees' initial status is lower, they appraise a task-based jolt as more of an opportunity, increasing their belief that they can contribute and their generosity, which ultimately causes them to gain status in the immediate aftermath of the jolt. Our findings offer valuable insights into how and why organizational-level change can indirectly influence microlevel interpersonal behaviors (generosity) that, in turn, affect status hierarchies within the organization. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Sexing of Embryos at the Time of Twin Reduction: A Clinical Approach.

This study provides new unique information on bovine twin pairs during the late embryonic period (28-34 days of pregnancy) in relation to (1) a predictive ultrasound measurement that was differential for sexing heterosexual twins; (2) intrauterine embryonic growth patterns in twin pairs; and (3) a higher vulnerability of female embryos compared to males following an induced embryo reduction in heterosexual twins. The study population comprised 92 dairy cows carrying bilateral twins. A length difference between co-twins equal to or greater than 25% in around 50% of pregnancies served to determine the sex of embryos with 100% accuracy in heterosexual twins, which was assessed four weeks later on the remaining fetus after twin reduction. The apparent rates of growth of twin pairs and of individual male and female embryos from day 28 to 34 of gestation were similar to established growth pattern standards for singletons. Mean embryo sizes in relation to gestational age were smaller by some 5 days' growth equivalent in twins compared to singletons. After the reduction in the female embryo in heterosexual twins, the risk of male embryo loss was null. This new information allowed for sex selection at the time of twin reduction.

One Year of Civil Family Law in the United Arab Emirates: A Preliminary Assessment

Abstract This article provides a preliminary commentary on the new civil family law regime introduced in the emirate of Abu Dhabi in November 2021 which, since February 2023, applies nationwide through the adoption of a federal statute on civil personal status. Abu Dhabi’s Law No. 14 of 2021, its accompanying Procedural Regulations, and the more recent Federal Law No. 41 of 2022 have introduced legal concepts, such as civil marriage, no-fault divorce, and joint custody, as well as potentially adoption, which have previously been non-existent for both the local and the large foreign population in the United Arab Emirates. The new statutes thereby stand in sharp contrast to the family law system to which the local Muslim population is still subject. This article assesses the new provisions against the background of the federal Muslim family law regime, established patterns of family law jurisprudence in the country, and early case law in the newly established Civil Family Court in Abu Dhabi.

Refrigerant overheating in the compression circuit air heat pump

The authors considered the processes of phase transformation of the working fluid in the compression unit of the freon circuit in the section “thermal expansion valve (TEV) - evaporator - compressor”. By adjusting the expansion valve under the conditions of the bubble mode of boiling of the refrigerant, the evaporation process takes place, accompanied by the achievement of a certain excess of steam temperature. Determination of rheological parameters (droplet size, vapor viscosity, refrigerant droplet vaporization rate) is necessary so that when moving from the throttle valve (TEV) to the compressor inlet, they have time to go into the vapor phase or return to the mass of boiling liquid. The article presents the results of an analytical calculation of the parameters of the kinetics of evaporation of Freon droplets as they move in a steam flow. The results of such an analysis make it possible to formulate requirements for the optimal droplet size in the created vapor-liquid mixture in order to ensure their maximum evaporation and the required thermal efficiency of the AHP as a whole. The established patterns of evaporation of refrigerant droplets can be used to select the design and operation of the AHP.

Spectral reflectance analysis of abandoned agricultural lands in the Central Russian forest-steppe using Sentinel-2 satellite data

The article considers the spectral response of post-agrogenic landscapes in the forest-steppe zone based on Sentinel-2 data. The study was carried out on the territory of the Central Chernozem region. The type of forest that forms on abandoned agricultural land has a statistically significant effect on the spectral response in most Sentinel-2 bands. The reflectance of abandoned lands with deciduous and coniferous species is statistically significantly different in most bands. The reflectance of abandoned lands with mixed forests does not differ statistically significantly from other types of post-agrogenic landscapes. The reflectance of abandoned lands is inversely related to their forest cover in most Sentinel-2 bands. The strongest correlation with forest cover is typical for red (Band 4) and SWIR (Band 11, 12) ranges for all post-agrogenic landscape types. In the same bands, there are statistically significant differences between most of forest cover gradations of post-agrogenic landscapes. The established patterns make it possible to use the reflectance in the red (Band 4) and SWIR MSI bands (11, 12) to assess the forest cover of post-agrogenic landscapes.

Socio-Cultural and Economic Consequences of Forced Marriages A Case Study of District Swabi Tehsil Razzar

The institution of marriage was one of the universal social institutions developed to manage and regulate the existence of people. Forced marriage is a type of marriage in which a couple is married without their consent or against their will. Conventional marriage is the established societal pattern through which two or more individuals form a family, whereas forced marriage is a sort of marriage in which a couple is married against their choice.. The purpose of this study is to analyze the socio-cultural as well as economic effects that forced marriages have on the Pashtun culture. Tehsil Razar, which is located in the Swabi area, served as the study's primary location. In order to collect information, we used techniques of simple random sampling on 120 female respondents from the entire population of tehsil Razar. This was done for the aim of data collecting. The literature provided a comprehensive questionnaire that was adapted for use, and it was analysed descriptively using Statistical Software for the Social Sciences (SPSS). The current study concluded that in Pashtun culture, forced marriage has become the norm in terms of both the customs and traditions surrounding marriage. The vast majority of the young women are considered "other property," despite their ages ranging from under 18 to over 18. The custom of being married at a young age is deeply ingrained in Pashtun culture since it is believed to bring dignity to the family. Despite the fact that it is perceived to be a financial strain on households. One of the primary reasons for forced marriages in Pashtun society is the lack of education and the ignorance of the parents, both of which contribute to domestic abuse and deprive individuals of their rights as well as their physical and mental wellbeing.