Environmental Components Research Articles

Effectiveness of internal controls mechanisms in preventing and detecting fraud

This review examines the effectiveness of internal control mechanisms in preventing and detecting fraud within organizations. Internal control mechanisms are essential components of corporate governance, designed to safeguard assets, ensure the accuracy of financial records, and promote operational efficiency. The study begins by defining internal controls and their critical role in fraud prevention and detection, highlighting the significance of a robust control environment. The components of the internal control environment, risk assessment, control activities, information and communication, and monitoring activities are discussed to provide a comprehensive understanding of their structure and function. Preventive controls, such as segregation of duties, authorization processes, and access controls, are analyzed to assess their role in minimizing the risk of fraud occurrence. Case studies and examples of organizations with effective preventive measures are presented to illustrate best practices. The challenges and limitations faced by organizations in implementing preventive controls are also explored. Detective controls, including reconciliation processes, internal audits, and whistleblower hotlines, are evaluated for their ability to identify and expose fraudulent activities. The review reviews case studies demonstrating the success of detective controls in uncovering fraud and discusses the obstacles organizations encounter in maintaining effective detection mechanisms. The evaluation section of the study focuses on metrics and indicators used to assess the effectiveness of internal controls, such as the reduction in fraud incidents and increased detection rates. Tools and techniques for evaluation, including internal and external audits, are examined to understand their role in ensuring control effectiveness. The review concludes by offering best practices for enhancing internal control mechanisms, emphasizing continuous monitoring, employee training, and the adoption of advanced technologies. The critical role of management in fostering a culture of ethical behavior and supporting internal audit functions is underscored. Recommendations for organizations and directions for future research are provided to guide ongoing efforts in fraud prevention and detection. Keywords: Fraud Prevention, Internal Control, Detective Control.

Stimuli-Responsive Nanocomposite Hydrogels for Oral Diseases.

Oral diseases encompassing conditions such as oral cancer, periodontitis, and endodontic infections pose significant challenges due to the oral cavity's susceptibility to pathogenic bacteria and infectious agents. Saliva, a key component of the oral environment, can compromise drug efficacy during oral disease treatment by diluting drug formulations and reducing drug-site interactions. Thus, it is imperative to develop effective drug delivery methods. Stimuli-responsive nanocomposite hydrogels offer a promising solution by adapting to changes in environmental conditions during disease states, thereby enabling targeted drug delivery. These smart drug delivery systems have the potential to enhance drug efficacy, minimize adverse reactions, reduce administration frequency, and improve patient compliance, thus facilitating a faster recovery. This review explores various types of stimuli-responsive nanocomposite hydrogels tailored for smart drug delivery, with a specific focus on their applications in managing oral diseases.

Long-Term Culture of Human Pluripotent Stem Cells in Xeno-Free Condition Using Functional Polymer Films.

Human pluripotent stem cells (hPSCs), encompassing human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs), hold immense potential in regenerative medicine, offering new opportunities for personalized cell therapies. However, their clinical translation is hindered by the inevitable reliance on xenogeneic components in culture environments. This study addresses this challenge by engineering a fully synthetic, xeno-free culture substrate, whose surface composition is tailored systematically for xeno-free culture of hPSCs. A functional polymer surface, pGC2 (poly(glycidyl methacrylate-grafting-guanidine-co-carboxylic acrylate)), offers excellent cell-adhesive properties as well as non-cytotoxicity, enabling robust hESCs and hiPSCs growth while presenting cost-competitiveness and scalability over Matrigel. This investigation includes comprehensive evaluations of pGC2 across diverse experimental conditions, demonstrating its wide adaptability with various pluripotent stem cell lines, culture media, and substrates. Crucially, pGC2 supports long-term hESCs and hiPSCs expansion, up to ten passages without compromising their stemness and pluripotency. Notably, this study is the first to confirm an identical proteomic profile after ten passages of xeno-free cultivation of hiPSCs on a polymeric substrate compared to Matrigel. The innovative substrate bridges the gap between laboratory research and clinical translation, offering a new promising avenue for advancing stem cell-based therapies.

Structure and molecular-level transformation for oxidation of effluent organic matters by manganese oxides

As important organic components in water environments, effluent organic matters (EfOMs) from wastewater treatment plants are widely present in Mn-rich environments or engineered treatment systems. The redox interaction between manganese oxides (MnOx) and EfOMs can lead to their structural changes, which are crucial for ensuring the safety of water environments. Herein, the reactivities of MnOx with EfOMs were evaluated, and it was found that MnOx with high specific surface area, active high-valent manganese content and lattice oxygen content (i.e., amorphous MnO2) possessed stronger oxidizing ability towards EfOMs. Accompanying by EfOMs oxidation, Mn(IV) and Mn(III) were reduced into Mn(II), with Mn(III) as the significant active species. Through molecular-level transformation analysis by ultrahigh mass spectrometry (FT-ICR MS), the highly reactive compounds in EfOMs were clearly determined to be that with more aromatic and unsaturated structures, especially lignin-like compounds (the highest content in EfOMs (over 60 %)). EfOMs were oxidized by amorphous MnO2 into products with lower humification index (0.60 vs. 0.46), smaller apparent molecular weight (386.94 Da vs. 368.68 Da), and higher biodegradability (BOD5/COD: 0.12 vs. 0.78). This finding suggested that redox reactions between MnOx and EfOMs might alter their abiotic and biotic behaviors in receiving water environments.

In-situ nanoscale precipitation behavior and strengthening mechanism of WC/IN718 composites manufactured by laser powder bed fusion

Nickel matrix composites (NMCs) have received much attention as they show excellent high temperature performances, which could meet the demand for hot-end components in severe environments. In this study, the duplex in-situ nanoscale carbides and oxides reinforcing IN718 were fabricated by laser powder bed fusion (LPBF) and addition of submicron WC particles. The microstructural features and mechanical properties were investigated with variations of WC content (0, 0.5, 2, and 4 wt%). The columnar dendrites with strong <001> texture that boundary distributed continuous Laves phase were found in the LPBF-processed IN718. Incorporating WC led to higher laser absorption and processability, whereas it also decreased the anisotropy of the matrix featured by weak texture index. With an optimized content of 2 wt%, the WC was dissolved into W and C atoms under laser irradiation, which promoted the homogeneous precipitation of intergranular cubic (Nb, Ti)C (∼50 nm) and intragranular spherical Al2O3 (∼20 nm). These precipitates would for heterogenous nucleation to refine grains (∼12.6 μm) and bring about high-density dislocations. The yield strength (YS) and ultimate tensile strength (UTS) increased by 28.8% and 26.5%, respectively, while maintaining high elongation compared with reported NMCs, demonstrating a favorable strength-ductility combination. Finally, the mechanism of microstructure evolution and strengthening was elucidated.

Climate sensitivity of natural hazards processes in mountain regions: A fuzzy logic approach

Natural hazard processes, as an inherent component of mountain environments, react sensitively to global warming. The main drivers of these changes are alterations in the amount, intensity or type of precipitation, glacier melting, or thawing of permafrost ice. The hazard responses can involve a change in hazard intensity or frequency (increasing or decreasing), a shift in their location or, a shift from one type of hazard to another. As climate change impacts vary in space and time, this variability must be considered when planning measures to protect populations and infrastructure from hazardous processes. To support this, we developed a method for assessing the climate sensitivity of small individual rock releases and larger rockfall processes. The method is based on a fuzzy logic approach and uses highly resolved climate scenario data, allowing application on a regional or even larger scale.The application in a study area of 700 km2 in the central Valais (Switzerland) shows that the impacts of climate change on natural hazard processes can vary quite substantially across small spatial scales. Generally, an increase in rockfall frequency and magnitude is simulated under future warming scenarios, especially at higher altitudes. However, at lower elevations and on south-exposed slopes, a decrease in freeze-thaw cycles leads to a decrease in material availability. This knowledge is essential in discussions of how climate change should be considered in hazard and disaster management.

Anti-Corrosion SiOx-Doped DLC Coating for Raster Steel Linear Scales

In this study, we investigated the efficacy of SiOx-doped diamond-like carbon (DLC) films for enhancing the corrosion resistance of raster steel linear scales. The research work highlights the significant role of DLC film materials in enhancing corrosion resistance, making them a promising solution for various industrial applications. The Raman spectroscopy analysis of SiOx-doped DLC films, synthesized via a direct ion beam technique with HMDSO vapor, revealed prominent D and G bands characteristic of amorphous carbon materials, with a high degree of disorder indicated by an ID/IG ratio of 1.85. X-ray diffraction patterns confirmed the amorphous nature of the SiOx-doped DLC films and the minimal impact of the DLC deposition process on the underlying crystalline structure of steel. UV–Vis-NIR reflectance spectra of SiOx-doped DLC on stainless steel demonstrated improvements in the blue wavelength region compared to stainless steel with ripples alone, which is beneficial for applications utilizing blue light. Corrosion tests, including immersion in a 5% salt solution and salt spray testing, showed that SiOx-doped DLC-coated stainless steel exhibited superior corrosion resistance compared to uncoated steel, with no significant signs of corrosion observed after extended exposure. These findings underscore the potential of SiOx-doped DLC coatings to provide long-term corrosion protection and maintain the structural integrity and surface quality of steel components in harsh environments.

Study of Deep Learning in Medical Education: Opportunities, Achievements and Future Challenges.

In this era of progress, interest has developed regarding advancing deep learning (DL) in medicine. However, there has been reluctance to use deep learning, particularly among medical educators. The limitations of previous research were examined in this study, along with the extent to which DL can be used in medical education and its potential impact on educational quality. We were interested in discussing DL's prospects, and determining whether we could benefit from it in medical education. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocol was used to manage this review procedure. Six databases were searched carefully to obtain relevant studies. Our search identified 981 articles from the database based on our standards. After filtering the duplicated articles, 11 studies were included in the systematic review. The results showed that DL applications attracted researchers' attention in the medical and education technology owing to their effectiveness to provide the personalized assistance and feedback. Furthermore, the majority of research concentrated on teaching medical students how to utilize DL applications in the classroom, and all of them tried to improve medical students' proficiency with DL instruments in practical applications. Deep learning components in medical learning environments have two segments-in the educational settings like speech recognition or Video content analysis for affecting students' learning, and in the medical settings, applying deep learning from diagnosis to prevention. An integration of them can work better in medical education. Medical education uses DL to improve the students' education. DL is a powerful instrument which has become more famous in terms of superb outcomes. Besides, using DL in medical education is likely to continue as a hotly debated area of research and a well-known classroom strategy.

EDUCATIONAL ENVIRONMENT POTENTIAL TO IMPROVE CADET TRAINING QUALITY

The article considers various conceptual approaches to the conceptualization of educational environments. Its main components are considered. Directions and indicators influencing the improvement of the quality of education are highlighted. Prior directions in the educational environment of military educational organizations of higher education (military education organizations) influencing the quality of military-professional education are defined. Attention is focused on the fact that understanding its main components and the relationships between them will allow us to develop and implement effective strategies for improving the quality of training for military personnel. It is concluded that it is necessary to constantly monitor and study the educational environment to timely adapt its components to modern life conditions that affect the quality of military professional education. The purpose of the article is to identify the components of the educational environment of military educational institutions, the development and improvement of which will lead to the improvement of the quality of military professional education. Method and methodology. The research is based on the methods of studying and analyzing scientific publications, systematizing the studied information, and searching for optimal solutions. Results. The components of the educational environment of a military educational organization, which have a direct impact on the quality of military professional education, are described. Attention is paid to the necessity of continuous improvement and development of the components of the educational environment of a military educational organization, taking into account its variability and dependence on economic, political, and social changes in society. Scope of application of the results. The obtained results can be applied to the didactics of higher military education in order to improve the quality of military professional education.

Smart Cities towards Artificial Intelligence

The creation of smart cities has come a long way in recent years, especially in domains that use AI, such IoT-based components, security systems, smart living options, and environmental monitoring. These advancements seek to build surroundings that meet human requirements by utilizing cutting edge technologies such as automated parking, smart healthcare, and seismic monitoring systems. Even with these encouraging advancements, the current generation of smart cities is still unable to attain genuine autonomy, particularly when it comes to component-level autonomous situation management and decision-making. The transformational perspective proposed in this work views the constituent components of smart environments as self-governing agents with the ability to make decisions. The purpose of these autonomous agents is to improve security and smart living by being able to self-manage and react automatically to different situations. Such autonomous agents can be integrated to accomplish the goal of artificially intelligent smart cities. In smart cities, autonomous agents may behave pro-actively without human involvement by continually monitoring and analyzing data, anticipating possible problems, and taking proactive actions. In the context of smart healthcare, these agents may, for example, track a patient's vitals in real time, anticipate possible health emergencies, notify medical personnel, or even start emergency procedures. Autonomous agents may dynamically assign parking spots in the context of smart car parking based on real-time data, maximizing space use and minimizing traffic congestion. Agents that can autonomously manage emergency actions, such as directing people to safety and managing infrastructure to minimize damage, might be beneficial for earthquake detecting systems. As autonomous entities endowed with decision-making skills are included, we are moving closer to truly intelligent cities. Because of these agents' capacity for independent operation and quick response to changing circumstances, smart cities are able to offer a better quality of security and service while accommodating the changing demands of its residents. As a result, smart cities that have these intelligent agents installed will be more responsive, efficient, and resilient—ultimately capturing the spirit of artificial intelligence in urban planning.

LEGAL REGULATION OF THE RIGHT OF OWNERSHIP OF NATURAL RESOURCES IN THE ADOPTION OF AMENDMENTS TO THE CONSTITUTION OF THE REPUBLIC OF KAZAKHSTAN

The article considers some issues of legal regulation of the ownership of natural resources. Analysis of the problems of the content of the real right to natural resources under consideration and related legal relations, as well as consideration of effective recommendations for its development and improvement based on the study of the fundamental principles is the purpose of writing the work. The relevance of the topic is justified by the social value of the realization of the right of ownership of natural resources for the population and the state in terms of meeting their needs. The use of general and special research methods in interaction is necessary to substantiate the author's opinion. The specificity of the object of research consists in the impossibility of isolating a separate natural resource from the environment, therefore it must be considered in interaction with it. The paper deals with the content of the concept of ownership of natural resources, which is complicated by the lack of a definition of the concept of "natural resources" in the legislation. The application of this institution in legislation and law enforcement practice along with the concept of "components of the natural environment" creates difficulties, especially in determining the priority in regulating the ownership of natural resources by civil or environmental (natural resource) legislation. This issue becomes relevant in the light of the adoption of amendments to the Constitution, in particular, regarding article 6. The constitutional provision on the ownership of natural resources by the people requires amendments to other normative legal acts regulating relevant issues in relation to this right. By the resolution of the Constitutional Council, this property is public law. In this regard, the question of applying the state property regime to this property may be controversial, since state and public property are different concepts in which state and public interests are the objects of the goals pursued.

Supportive Learning Environment and Assertive Classroom Management Strategies as a Contributing Factor of the Academic Resiliency of T.L.E. Students

This study investigated the effects of supportive learning settings and assertive classroom management tactics on students' academic resilience. Using a descriptive-correlational research methodology, 254 junior high school students from a public secondary school in the Division of Davao del Norte were chosen using stratified random sampling. Using three adopted questionnaires and statistical tools such as mean, Pearson r, and regression analysis, the study demonstrates a very high degree of supportive learning environment, with high levels of assertive classroom management strategies and academic resilience. Significant correlations were discovered between numerous components of supportive learning environments and assertive classroom management practices, which influenced students' academic resilience. The study emphasizes the critical role of supportive learning settings and assertive classroom management practices in developing academic resilience, particularly in technical livelihood education. Recommendations include developing targeted interventions based on strengths observed in supportive learning environments, providing professional development opportunities for educators, implementing specialized interventions targeting specific qualities associated with academic resilience, and fostering a culture of continuous review and development within educational institutions.

Influence of Food Environments on Dietary Habits: Insights from a Quasi-Experimental Research.

Nutrition is a vital factor that exerts a profound and direct impact on health. Food environments significantly influence individuals' dietary behaviors, health outcomes, and overall food security. Individuals in food deserts and food swamps do not have access to healthier food options. And in both cases, the emphasis is primarily on the physical configuration of the environment as it relates to food availability. This quasi-experimental study aims to investigate the impact of two different food environments (defined to include a social component) on food choices. A total of 246 participants were surveyed by telephone, half of whom were primed with Scenario A (a food environment deficient in healthy options and cues that support and reinforce healthier choices) and half were primed with Scenario B (an environment with an abundance of healthy food options and cues that support and reinforce healthy eating). Ordered logit regression was used for analysis. The results show significant differences in likely food consumption between the groups. Individuals in Scenario B were found to be 4.48 times more likely to consume fruits and vegetables. In addition, it was determined that being a woman increases the probability of consuming more fruits and vegetables by 0.92 times (1/0.52-1), and adherence to a healthy diet increases by 3.64 times. Age and race were not significant predictors. This study highlights the crucial role of environmental factors in shaping dietary habits and underscores the importance of the social components of the food environment in promoting the adoption of healthier dietary habits. Based on these findings, policymakers should prioritize developing strategies that go beyond providing physical access and consider social aspects of the environment in promoting healthy eating habits to improve public health and bolster the food security of communities.

The mechanical and tribological properties of polyether ether ketone coated by diamond-like carbon film with plasma-induced transition layer

Polyether ether ketone (PEEK) has been broadly utilized in aerospace due to its excellent properties. Nevertheless, when applied as sealing components in harsh environments, virgin PEEK still faces defects in mechanical behavior and wear resistance. To address these issues, the deposition of diamond-like carbon (DLC) films has been employed as a viable solution. In this study, the DLC film with plasma-induced transition layer was fabricated on PEEK via direct current magnetron sputtering technology. Compared with previous studies, the evolutions of interfacial structures and plasma-induced layer were investigated, and their roles on the tribological performance of PEEK/DLC were analyzed in detail. Results show that an increase in etching duration promotes the formation of cauliflower pits and enhances the hardness of plasma-induced layer on PEEK, which are facilitated by high-energy plasma bombardment. When the etching time comes to 20 min, these features endow PEEK/DLC with good interfacial adhesion and mechanical properties. Besides, the cauliflower pits could fill debris and help to form graphitized transfer films. The friction coefficient and wear rate of PEEK/DLC both exhibit a declining trend as the etching duration prolongs. Notably, compared to virgin PEEK, the tribological performance of PEEK/DLC with 20-min etching displays lower friction coefficient of 0.2 and lower wear rate of 1.22 × 10−8 mm3/N·m. Finally, a wear failure mechanism for PEEK/DLC with 20-min etching was proposed. This provides a simple and effective approach to improve the tribological behavior of carbon-based films applied on PEEK, it also assists in the development of efficiently wear-resistant materials for aerospace.

Seeking systems-based facilitators of safety and healthcare resilience: a thematic review of incident reports.

Patient safety incident reports are a key source of safety intelligence. This study aimed to explore whether information contained in such reports can elicit facilitators of safety, including responding, anticipating, monitoring, learning, and other mechanisms by which safety is maintained. The review further explored whether, if found, this information could be used to inform safety interventions. Anonymized incident reports submitted between August and October 2020 were obtained from two large teaching hospitals. The Systems Engineering Initiative for Patient Safety (SEIPS) tool and the resilience potentials (responding, anticipating, monitoring, and learning) frameworks guided thematic analysis. SEIPS was used to explore the components of people, tools, tasks, and environments, as well as the interactions between them, which contribute to safety. The resilience potentials provided insight into healthcare resilience at individual, team, and organizational levels. Sixty incident reports were analysed. These included descriptions of all the SEIPS framework components. People used tools such as electronic prescribing systems to perform tasks within different healthcare environments that facilitated safety. All four resilient capacities were identified, with mostly individuals and teams responding to events; however, monitoring, anticipation, and learning were described for individuals, teams, and organizations. Incident reports contain information about safety practices, much of which is not identified by traditional approaches such as root cause analysis. This information can be used to enhance safety enablers and encourage greater proactive anticipation and system-level learning.

Conserving ecosystem integrity: Ecological theory as a guide for marine protected area monitoring.

Global policies increasingly focus on the importance of maintaining or improving the integrity of ecosystems, but defining, assessing, and monitoring integrity in marine protected areas (MPAs) remains a challenge. In this paper, we conceptualized ecological integrity along dimensions of heterogeneity and stability containing seven components: physical structure, diversity, function, persistence, resistance, resilience, and natural variability. Through a structured literature search, we identified indicators and metrics used for quantifying ecosystem status components in the marine environment, then reviewed MPA management plans worldwide for inclusion of these components. We evaluated 202 papers applying 83 ecological indicators built from 72 metrics. Ecosystem components were most comprehensively addressed by metrics of taxa presence, organisms count, and area occupied by benthic organisms, and community structure, biomass, and percent cover indicators. Of the 557 MPA management plans we reviewed globally, 93% used at least one ecosystem status term or its synonym in an ecologically relevant context, but 39% did not address any components of stability. In particular, resistance was mentioned in only 1% of management plans, but in some cases it may be inferred from indicators and metrics used to track the best addressed component in management plans, diversity. Plans for MPAs with both an ecological/biological purpose and a research and education purpose contained ecosystem status terms more frequently than other plans, suggesting that engagement with the scientific community may have improved the application of these terms. An improved understanding of how to operationalize and measure ecological integrity can help MPA monitoring and management.

Maintenance Operations on Cloud, Edge, and IoT Environments: Taxonomy, Survey, and Research Challenges

The emergence of the Internet of Things (IoT) introduced new classes of applications whose latency and bandwidth requirements could not be satisfied by the traditional Cloud Computing model. Consequently, the Internet Technology community promoted the cooperation of two paradigms, Cloud Computing and Edge Computing, combining large-scale computing power and real-time processing capabilities. A significant management challenge in such complex infrastructure concerns the development of efficient maintenance strategies to preserve the environment’s performance and security. While the abundant resources from the academic literature could support the design of novel maintenance solutions, extracting actionable insights from the existing approaches is challenging, given the massive number of published papers. Furthermore, existing review papers, which could help summarize the state-of-the-art, scope their investigations to the maintenance of certain components in particular scenarios. This work fills this gap with a broader literature analysis that covers maintenance strategies targeting physical and logical components in cloud, edge, and IoT environments. First, we introduce a taxonomy that organizes existing solutions according to several characteristics. Then, we review the literature following the taxonomy structure to facilitate the understanding of the research landscape and the comparison between existing works. Finally, we shed light on open challenges that represent promising research directions.

Lactate supports cell-autonomous ECM production to sustain metastatic behavior in prostate cancer

Extracellular matrix (ECM) is a major component of the tumor environment, promoting the establishment of a pro-invasive behavior. Such environment is supported by both tumor- and stromal-derived metabolites, particularly lactate. In prostate cancer (PCa), cancer-associated fibroblasts (CAFs) are major contributors of secreted lactate, able to impact on metabolic and transcriptional regulation in cancer cells. Here, we describe a mechanism by which CAF-secreted lactate promotes in PCa cells the expression of genes coding for the collagen family. Lactate-exploiting PCa cells rely on increased α-ketoglutarate (α-KG) which activates the α-KG-dependent collagen prolyl-4-hydroxylase (P4HA1) to support collagen hydroxylation. De novo synthetized collagen plays a signaling role by activating discoidin domain receptor 1 (DDR1), supporting stem-like and invasive features of PCa cells. Inhibition of lactate-induced collagen hydroxylation and DDR1 activation reduces the metastatic colonization of PCa cells. Overall, these results provide a new understanding of the link between collagen remodeling/signaling and the nutrient environment exploited by PCa.

РОЗВИВАЛЬНЕ ОСВІТНЄ СЕРЕДОВИЩЕ НА УРОКАХ БІОЛОГІЇ: КЛЮЧОВІ ПРИНЦИПИ ТА ПРАКТИЧНІ ПІДХОДИ

The article deals with the issue of organising developmental educational environment at biology lessons.The study emphasises that modern education requires the introduction of new approaches that will help to form competences, develop critical thinking, abilities, creativity and independence of students. The purpose of the article is to substantiate the components, key principles and practical approaches to the organisation of developmental educational environment at biology lessons. Based on the analysis of modern researches, the article describes modern approaches to the definition of the concepts of «educational environment», «learning environment», «developmental educational environment». The authors have found that the educational environment is a multimodal space that should be in line with modern technologies, methods, and forms of learning.The components of the developmental educational environment are substantiated: target, value, technological, psychological, informational, subject-spatial and socio-cultural. The article presents practical approaches (developmental, competence and activity-based) and key principles for creating developmental educational environment at biology lessons (activity in learning, humanisation, problematic, relevant and timely knowledge, conscious participation of students in the educational process, freedom of choice of learning conditions). The authors note that developmental educational environment is a set of pedagogical conditions that contribute not only to the acquisition of knowledge but also to the development of skills and competencies, and create opportunities for students’ self-realisation. The authors of the article conclude that for the successful organization of the educational environment it is necessary to take into account its multifacedness, systematicity, complexity, as well as the need to improve technologies, methods and approaches for the purpose of the development of each individual. Key words: educational environment, developmental learning, developmental educational environment, didactic principles, practical approaches, biology lesson, education.

Influence of the atmospheric environment on spatial variation of lung cancer incidence in China.

Conducting this research contributes to a deeper understanding of the correlation between atmospheric environmental quality and lung cancer incidence, and provides the scientific basis for formulating effective environmental protection and lung cancer prevention and control strategies. Lung cancer incidence in China has strong spatial variation. However, few studies have systematically revealed the characteristics of the spatial variation in lung cancer incidence, and have explained the causes of this spatial variation in lung cancer incidence from the perspectives of multiple components of the atmospheric environment to explain this spatial variation in lung cancer incidence. To address research limitations, we first analyze the spatial variation and spatial correlation characteristics of lung cancer incidence in China. Then, we build a spatial regression model using GeoDa software with lung cancer incidence as the dependent variable, five atmospheric environment factors-particulate matter 2.5 (PM2.5) concentration, temperature, atmospheric pressure, and elevation as explanatory variables, and four socio-economic characteristics as control variables to systematically analyze the influence and intensity of these factors on lung cancer incidence. The results show that lung cancer incidence in China has apparent changes in geographical and spatial unevenness, and spatial autocorrelation characteristics. In China, the lung cancer incidence is relatively high in Northeast China, while some areas of high lung cancer incidence still exist in Central China, Southwest China and South China, although the overall lung cancer incidence is relatively low. The atmospheric environment significantly affects lung cancer incidence. Different elements of the atmospheric environment vary in the direction and extent of their influence on the development of lung cancer. A 1% increase in PM2.5 concentration is associated with a level of 0.002975 increase in lung cancer incidence. Atmospheric pressure positively affects lung cancer incidence, and an increase in atmospheric pressure by 1% increases lung cancer incidence by a level of 0.026061. Conversely, a 1% increase in temperature is linked to a level of 0.006443 decreases in lung cancer incidence, and a negative correlation exists between elevation and lung cancer incidence, where an increase in elevation by 1% correlates with a decrease in lung cancer incidence by a level of 0.000934. The core influencing factors of lung cancer incidence in the seven geographical divisions of China exhibit variations. This study facilitates our understanding of the spatial variation characteristics of lung cancer incidence in China on a finer scale, while also offering a more diverse perspective on the impact of the atmospheric environment on lung cancer incidence.