Building load prediction plays an important role in building energy savings and mechanical and electrical system optimization control. The dynamic energy consumption can be accurately calculated using the traditional physical energy simulation method that entails a complex setup and verification process due to the numerous input parameters required. It is also difficult to change the physical model once it has been determined. The data-mining method is fast in calculation and simple to use, but its prediction accuracy is limited by historical data quality. It is difficult to predict the load of new buildings without historical data. To solve these problems, this study proposes a hybrid building load prediction method for office buildings. The proposed method uses EnergyPlus to generate a building load database that includes than 25.14 million data cases, covering 35 types of building geometry and 2870 building examples. Based on the above database, the LightGBM algorithm was selected to extract feature variables that affect the load and build a load prediction model. The training results show that there are 24 key feature variables for office building load prediction. The hourly MAPE of the cooling load prediction model is 6.95 % and RMSE is 4.31 W/m2, and the hourly MAPE of the heating load prediction model is 7.09 % and RMSE is 11.64 W/m2 compared with EnergyPlus model. Two actual office buildings are selected as case studies to validate the model prediction accuracy. Results show that comparing predicted results with measured data, the hourly cooling load of the MAPE is 12.42 %. Coparing predicted results with actual heating load, daily MAPE is 7.97 %.