Cities encounter increasing risks and challenges under new development patterns, and digital economy (DE) can drive cities’ improved resilience to natural and social uncertainties. Based on data collected on the Yangtze River Economic Belt from 2011 to 2021, the development situation of the regional DE and urban resilience (UR) was measured, and the impact mechanisms of the DE on UR were analysed theoretically and empirically using a benchmark regression model. The findings are as follows: The benchmark test revealed that the DE development contributed significantly to UR in the region. The mediating effect test revealed that the DE improved UR through two pathways: industrial structure upgradation and energy restructuring. The moderating effect test suggested that environmental pollutant emissions had a negative moderating effect between the impact mechanisms of the DE, industrial structure, and energy structure and between the effects of industrial structure, energy structure, and UR, whereas CO2 emissions had a positive moderating effect between the impact mechanisms of DE and industrial structure. Heterogeneity analysis indicated that the DE contributed positively to the UR except in the upstream region, where the coefficient of the DE was insignificant. Overall, this study highlights the crucial role of the DE in improving UR and elucidates the theoretical impact mechanisms of environmental pollution control and carbon reduction measures on UR.
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