The layer structures of shale greatly influence its crack propagation behavior. Nevertheless, the correlation between crack extension rates and mechanical parameters has not been well studied, especially, the relationship between the energy release rate and crack propagation rates. Consequently, there are unresolved issues regarding the effects of layer structure on the propagation of cracks in shale. In this paper, a series of three-point compressive loading tests were conducted on seven groups of shale semi-circular bend (SCB) samples with an inclination angle of 0°-90°. The entire fracture process was captured using the ultrafast time-resolution method with a resolution capability of up to 15 picoseconds. In addition, fracture surface information was obtained by a high-precision laser three-dimensional scanning system, and this information was utilized to categorize crack propagation behaviors, such as propagation along weak planes, intermittent penetration, and deflection penetration. Furthermore, a quantitative relationship was established between the energy-release rate and crack propagation rate, based on the first law of thermodynamics and the maximum energy release rate (MERR) criteria proposed by Griffith. The experimental results showed that there is a linear relationship between the energy-release rate and the propagation rate, which meets well with the established relationship. The experimental results indicated that symmetric loading does not result in significant angle localization during crack initiation. This suggests that crack propagation behavior in shale is a reflection of the interplay between energy-release rates and fracture resistance. Finally, this study evaluated the influence of the bedding angle on dissipated energy, and absorbed energy.